Sponsor of the Day:
Jerkmate
https://pdb101.rcsb.org/motm/316
PDB-101: Molecule of the Month: Insect Odorant Receptors
Protein complexes that allow insects to detect a wide variety of volatile compounds
pdb 101 moleculemonthinsectodorantreceptors
https://pdb101.rcsb.org/news/699dfde8dc019510fc5969e9
PDB-101: March 16-22: Brain Awareness Week
PDB-101: Training, Outreach, and Education portal of RCSB PDB
march 16 22brain awareness weekpdb 101
https://pdb101.rcsb.org/learn/paper-models/dengue-virus
PDB-101: Learn: Paper Models: Dengue Virus
Atomic structures of dengue virus are giving new hope for creation of a vaccine
pdb 101 learnpaper modelsdengue virus
https://pdb101.rcsb.org/motm/272
PDB-101: Molecule of the Month: Secretory Antibodies
Secretory immunoglobulins are our most abundant antibodies, providing a first line of defense against pathogens.
pdb 101 moleculemonthsecretoryantibodies
https://pdb101.rcsb.org/sci-art/goodsell-gallery/vascular-endothelial-growth-factor-vegf-signaling
PDB-101: Goodsell Gallery: Vascular Endothelial Growth Factor (VegF) Signaling
Cross section of two cells showing the VegF signaling pathway and some of its consequences.
pdb 101 goodsellgrowth factorgalleryvascularendothelial
https://pdb101.rcsb.org/train/training-events/enzymology
PDB-101: Teaching Enzymology with the Protein Data Bank: From Pandemic to Paxlovid (2023)
PDB-101: Training, Outreach, and Education portal of RCSB PDB
protein data bankpdb 101teachingenzymologypandemic
https://pdb101.rcsb.org/motm/302
PDB-101: Molecule of the Month: H5 Hemagglutinin
Sugar-binding protein on the surface of the H5N1 avian influenza virus
pdb 101 moleculemonthh5
https://pdb101.rcsb.org/motm/120
PDB-101: Molecule of the Month: Antifreeze Proteins
Small antifreeze proteins protect cells from damage by ice
pdb 101 moleculemonthantifreezeproteins
https://pdb101.rcsb.org/browse/infectious-disease
PDB-101: Browse: Infectious Disease
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browseinfectious disease
https://pdb101.rcsb.org/sci-art/goodsell-gallery/transfer-rna-and-gag-protein
PDB-101: Goodsell Gallery: Transfer RNA and Gag Protein
HIV-1 Gag protein binds to tRNA and ribosomes in the cytoplasm before assembling on the cell membrane.
pdb 101 goodsellgallerytransferrnagag
https://pdb101.rcsb.org/motm/254
PDB-101: Molecule of the Month: Cellulose Synthase
Plants build tough cellulose strands one sugar at a time.
pdb 101 moleculemonthcellulosesynthase
https://pdb101.rcsb.org/motm/155
PDB-101: Molecule of the Month: Vitamin D Receptor
Vitamin D helps regulate the use of calcium throughout the body
pdb 101 moleculemonthvitaminreceptor
https://pdb101.rcsb.org/sci-art/goodsell-gallery/measles-virus-proteins
PDB-101: Goodsell Gallery: Measles Virus Proteins
Measles Virus Proteins (2019) by David S. Goodsell
pdb 101 goodsellmeasles virusgalleryproteins
https://pdb101.rcsb.org/train/training-events/mmcif
PDB-101: Use PDB data to their full extent: Understanding PDBx/mmCIF
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101use datafull extentpdbx mmcifunderstanding
https://pdb101.rcsb.org/browse/biomolecules
PDB-101: Browse: Biomolecules
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browsebiomolecules
https://pdb101.rcsb.org/sci-art/goodsell-gallery/insulin-action
PDB-101: Goodsell Gallery: Insulin Action
Insulin Action (2016) by David S. Goodsell.
pdb 101 goodsellinsulin actiongallery
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-1000-hemoglobin
PDB-101: Geis Archive: Hemoglobin (1000)
pdb 101 geisarchive hemoglobin1000
https://pdb101.rcsb.org/learn/exploring-structural-biology-with-computed-structure-models-csms
PDB-101: Learn: Exploring Structural Biology with Computed Structure Models (CSMs)
Computational methods like AlphaFold2 and RoseTTAFold2 use structures in the PDB archive to predict the folding of proteins.
pdb 101 learncomputed structure modelsstructural biologyexploringcsms
https://pdb101.rcsb.org/sci-art/goodsell-gallery/myelin
PDB-101: Goodsell Gallery: Myelin
Myelin forms an insulating sheath around nerve axons
pdb 101 goodsellgallerymyelin
https://pdb101.rcsb.org/global-health/diabetes-mellitus/about/what-is-diabetes
PDB-101: Diabetes Mellitus: Diabetes Mellitus: About: What is Diabetes?
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101diabetes mellitus
https://pdb101.rcsb.org/motm/83
PDB-101: Molecule of the Month: Fibrin
Rod-shaped fibrin molecules link together to form blood clots
pdb 101 moleculemonthfibrin
https://pdb101.rcsb.org/browse/molecules-for-a-sustainable-future
PDB-101: Browse: Molecules for a Sustainable Future
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browsesustainable futuremolecules
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-0355-z-dna
PDB-101: Geis Archive: Z-DNA
In this sketch, Geis illustrates the left handed Z-form of double stranded deoxyribonucleic acid (DNA). Z-DNA is indicated by the zig-zag like pattern of the...
pdb 101 geisarchive zdna
https://pdb101.rcsb.org/learn/paper-models/trna
PDB-101: Learn: Paper Models: tRNA
Transfer RNA translates the language of the genome into the language of proteins
pdb 101 learnpaper modelstrna
https://pdb101.rcsb.org/sci-art/goodsell-gallery/mycoplasma-mycoides
PDB-101: Goodsell Gallery: Mycoplasma mycoides
Mycoplasma mycoides (2011) by David S. Goodsell. doi: 10.2210/rcsb_pdb/goodsell-gallery-011
pdb 101 goodsellgallerymycoplasma
https://pdb101.rcsb.org/motm/214
PDB-101: Molecule of the Month: Chimeric Antigen Receptors
T cells may be engineered with chimeric antigen receptors to attack cancer cells.
pdb 101 moleculechimeric antigenmonthreceptors
https://www.rcsb.org/news/feature/69937bc2dc019510fc5969e1
Take the PDB-101 User Survey and Win
Share your feedback and enter into a drawing for a Molecule of the Month-themed sticker set
pdb 101user surveytakewin
https://pdb101.rcsb.org/motm/motm-by-date
PDB-101: Molecule of the Month By Date
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 moleculemonthdate
https://pdb101.rcsb.org/more/about-pdb-101
PDB-101: About PDB-101
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101
https://pdb101.rcsb.org/browse/molecular-infrastructure
PDB-101: Browse: Molecular Infrastructure
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browsemolecularinfrastructure
https://pdb101.rcsb.org/motm/174
PDB-101: Molecule of the Month: GFP-like Proteins
GFP-like proteins found in nature or engineered in the laboratory now span every color of the rainbow
pdb 101 moleculemonthgfplikeproteins
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-0585-cytochrome-c-unbound
PDB-101: Geis Archive: Cytochrome c (unbound)
This illustration depicts the protein, Cytochrome c. The red structures represent the hydrophobic amino acids. The green structures represent the positively...
pdb 101 geisarchivecytochromeunbound
https://pdb101.rcsb.org/browse/cancer
PDB-101: Browse: Cancer
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browsecancer
https://pdb101.rcsb.org/motm/17
PDB-101: Molecule of the Month: Cyclooxygenase
Aspirin attacks an important enzyme in pain signaling and blood clotting
pdb 101 moleculemonth
https://pdb101.rcsb.org/sci-art/goodsell-gallery/last-universal-common-ancestor
PDB-101: Goodsell Gallery: Last Universal Common Ancestor
This speculative painting depicts the primordial cell that gave rise to all life on Earth.
pdb 101 goodsellcommon ancestorgallerylastuniversal
https://pdb101.rcsb.org/learn/paper-models/dna
PDB-101: Learn: Paper Models: DNA
Atomic structures reveal how the iconic double helix encodes genomic information
pdb 101 learnpaper modelsdna
https://pdb101.rcsb.org/motm/185
PDB-101: Molecule of the Month: Titin
The giant protein titin organizes the structure of muscle and gives them elasticity
pdb 101 moleculemonth
https://pdb101.rcsb.org/train/training-events/python
PDB-101: Python Scripting for Biochemistry & Molecular Biology | Part 1
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 pythonbiochemistry molecularscriptingbiologypart
https://pdb101.rcsb.org/sci-art/goodsell-gallery/red-blood-cell-cytoskeleton
PDB-101: Goodsell Gallery: Red Blood Cell Cytoskeleton
Cross section through a red blood cell membrane shows the distinctive cytoskeleton
pdb 101 goodsellred blood cellgallerycytoskeleton
https://pdb101.rcsb.org/motm/77
PDB-101: Molecule of the Month: Glucose Oxidase
Glucose oxidase measures blood glucose level in biosensors
pdb 101 moleculemonthglucoseoxidase
https://pdb101.rcsb.org/learn/coloring-books
PDB-101: Learn: Coloring Books
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 learncoloring books
https://pdb101.rcsb.org/motm/287
PDB-101: Molecule of the Month: ZAR1 Resistosome
Plants protect themselves from infection with immune system machines such as the resistosome
pdb 101 moleculemonth
https://pdb101.rcsb.org/motm/40
PDB-101: Molecule of the Month: RNA Polymerase
RNA polymerase transcribes genetic information from DNA into RNA
pdb 101 moleculerna polymerasemonth
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-0317-hemoglobin-s
PDB-101: Geis Archive: Hemoglobin S
Geis illustrates the hemoglobin s molecule as four nearly symmetrically arranged subunits with a mutation present in the beta chain.
pdb 101 geisarchive hemoglobin
https://pdb101.rcsb.org/sci-art/goodsell-gallery/ebola-virus
PDB-101: Goodsell Gallery: Ebola Virus
Ebola Virus (2014) by David S. Goodsell
pdb 101 goodsellebola virusgallery
https://pdb101.rcsb.org/motm/27
PDB-101: Molecule of the Month: Bacteriorhodopsin
Bacteriorhodopsin pumps protons powered by green sunlight
pdb 101 moleculemonth
https://pdb101.rcsb.org/motm/100
PDB-101: Molecule of the Month: Adrenergic Receptors
Adrenaline stimulates a G-protein-coupled receptor, priming us for action
pdb 101 moleculemonthadrenergicreceptors
https://pdb101.rcsb.org/train/training-events/models
PDB-101: Exploring Computed Structure Models on RCSB.org
PDB-101: Training, Outreach, and Education portal of RCSB PDB
computed structure modelspdb 101exploringrcsb
https://pdb101.rcsb.org/motm/68
PDB-101: Molecule of the Month: Neurotrophins
Neurotrophins guide the development of the nervous system
pdb 101 moleculemonth
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-0316-transfer-rna
PDB-101: Geis Archive: Transfer Ribonucleic Acid (tRNA)
pdb 101 geisribonucleic acidarchivetransfertrna
https://pdb101.rcsb.org/browse/peak-performance
PDB-101: Browse: Peak Performance
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browsepeak performance
https://pdb101.rcsb.org/sci-art/goodsell-gallery/casein-micelle-and-fat-globule-in-milk
PDB-101: Goodsell Gallery: Casein Micelle and Fat Globule in Milk
Illustration of a casein micelle and fat globule from milk
pdb 101 goodsellgallerycaseinmicellefat
https://pdb101.rcsb.org/sci-art/goodsell-gallery/influenza-virus
PDB-101: Goodsell Gallery: Influenza Virus
Cross section of influenza virus
pdb 101 goodsellinfluenza virusgallery
https://pdb101.rcsb.org/train/training-events/python2
PDB-101: Python Scripting for Biochemistry & Molecular Biology | Part 2
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 pythonbiochemistry molecularpart 2scriptingbiology
https://pdb101.rcsb.org/events/art-of-science
PDB-101: Art of Science
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101artscience
https://pdb101.rcsb.org/motm/39
PDB-101: Molecule of the Month: lac Repressor
A genetic circuit controls the production of lactose-utilizing enzymes in bacteria
pdb 101 moleculemonthlac
https://pdb101.rcsb.org/teach/molecular-immunology
PDB-101: Molecular Immunology
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101molecularimmunology
https://pdb101.rcsb.org/sci-art/goodsell-gallery/jcvi-syn3a-minimal-cell
PDB-101: Goodsell Gallery: JCVI-syn3A Minimal Cell
Cross-section through an entire JCVI-syn3A minimal cell showing an entire cellular proteome.
pdb 101 goodsellgalleryjcviminimalcell
https://pdb101.rcsb.org/motm/123
PDB-101: Molecule of the Month: P-glycoprotein
P-glycoprotein pumps toxic molecules out of our cells
pdb 101 moleculemonthglycoprotein
https://www.rcsb.org/news/699e5bb3dc019510fc5969ea
Take the PDB-101 User Survey and Win
Share your feedback and enter into a drawing for a Molecule of the Month-themed sticker set
pdb 101user surveytakewin
https://pdb101.rcsb.org/motm/204
PDB-101: Molecule of the Month: PD-1 (Programmed Cell Death Protein 1)
PD-1 and its ligands are a new target for cancer therapy
pdb 101 moleculecell deathmonthprogrammedprotein
https://pdb101.rcsb.org/sci-art/bezsonova-gallery
PDB-101: Irina Bezsonova Gallery
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101irinagallery
https://pdb101.rcsb.org/sci-art/geis-archive/about
PDB-101: About the Geis Digital Archive
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101digital archivegeis
https://pdb101.rcsb.org/sci-art/goodsell-gallery/reca-and-dna
PDB-101: Goodsell Gallery: RecA and DNA
RecA assists with the pairing of DNA strands during DNA repair.
pdb 101 goodsellgalleryrecadna
https://pdb101.rcsb.org/motm/240
PDB-101: Molecule of the Month: Hypoxia-Inducible Factors
HIF-α is a molecular switch that responds to changing oxygen levels.
pdb 101 moleculemonthhypoxiainduciblefactors
https://pdb101.rcsb.org/motm/253
PDB-101: Molecule of the Month: Expressome
In bacteria, ribosomes start building proteins as messenger RNA is being transcribed
pdb 101 moleculemonth
https://pdb101.rcsb.org/motm/243
PDB-101: Molecule of the Month: Voltage-gated Sodium Channels
Voltage-gated sodium channels transmit signals in a wave through the nervous system.
pdb 101 moleculemonthvoltagegatedsodium
https://pdb101.rcsb.org/learn/paper-models/zika-virus-with-and-without-antibodies
PDB-101: Learn: Paper Models: Zika Virus with and without antibodies
Atomic-level structures of Zika virus will help researchers better understand how the virus enters human cells and sets the stage for vaccine discovery and...
pdb 101 learnpaper modelszika viruswithoutantibodies
https://pdb101.rcsb.org/motm/52
PDB-101: Molecule of the Month: Growth Hormone
Growth hormone brings together two copies of its cellular receptor
pdb 101 moleculemonth growthhormone
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-0022-trypsin
PDB-101: Geis Archive: Trypsin
pdb 101 geisarchivetrypsin
https://pdb101.rcsb.org/learn/paper-models/paper-nucleic-acid-models-for-hands-on-education
PDB-101: Learn: Paper Models: Paper Nucleic Acid Models for Hands-on Education
Download templates for a set of paper models that can be cut from paper or card stock and used for demonstrations of the fundamentals of DNA structure, DNA...
pdb 101 learnpaper modelsnucleic acidhandseducation
https://pdb101.rcsb.org/browse/toxins-and-poisons
PDB-101: Browse: Toxins and Poisons
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browsetoxinspoisons
https://pdb101.rcsb.org/sci-art/goodsell-gallery/phage-based-covid-19-vaccine
PDB-101: Goodsell Gallery: Phage-based COVID-19 Vaccine
Genetically-engineered phages are being used to design coronavirus vaccines.
pdb 101 goodsellbased covid 19galleryphagevaccine
https://pdb101.rcsb.org/learn/paper-models/creating-paper-models-of-protein-domains
PDB-101: Learn: Paper Models: Creating Paper Models of Protein Domains
Download printable alpha helices and beta strand templates for hands-on exploration of many protein folding domains.
pdb 101 learnpaper modelscreatingproteindomains
https://pdb101.rcsb.org/learn/other-resources
PDB-101: Learn: Other Resources
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 learnresources
https://pdb101.rcsb.org/learn/paper-models/antibody
PDB-101: Learn: Paper Models: Antibody
A paper folding activity that explores the structure of an antibody
pdb 101 learnpaper modelsantibody
https://pdb101.rcsb.org/motm/46
PDB-101: Molecule of the Month: Trypsin
An activated serine amino acid in trypsin cleaves protein chains
pdb 101 moleculemonthtrypsin
https://pdb101.rcsb.org/learn/paper-models/g-protein-coupled-receptor-gpcr
PDB-101: Learn: Paper Models: G Protein-Coupled Receptor (GPCR)
GPCRs are a large family of membrane-embedded receptors, with structural features that have been preserved through the course of evolution. This model...
pdb 101 learng protein coupledpaper modelsreceptorgpcr
https://pdb101.rcsb.org/sci-art/goodsell-gallery/biosites-muscle
PDB-101: Goodsell Gallery: Biosites: Muscle
Biosites: Muscle (2005) by David S. Goodsell
pdb 101 goodsellgallery biositesmuscle
https://pdb101.rcsb.org/motm/221
PDB-101: Molecule of the Month: Human Papillomavirus and Vaccines
The capsid protein of papillomavirus is used in vaccines that prevent cervical cancer.
pdb 101 moleculehuman papillomavirusmonthvaccines
https://pdb101.rcsb.org/sci-art/goodsell-gallery/biosites-basement-membrane
PDB-101: Goodsell Gallery: Biosites: Basement Membrane
Biosites: Basement Membrane (2005) by David S. Goodsell.
pdb 101 goodsellgallery biositesbasement membrane
https://pdb101.rcsb.org/motm/88
PDB-101: Molecule of the Month: Clathrin
Three-armed clathrin triskelions are used to build molecular cages involved in transport
pdb 101 moleculemonth
https://pdb101.rcsb.org/events/video-challenge/the-challenge
PDB-101: Video Challenge
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101video challenge
https://pdb101.rcsb.org/motm/252
PDB-101: Molecule of the Month: Hepatitis C Virus Protease/Helicase
Structures of hepatitis C viral proteins have led to the discovery of direct-acting antivirals.
pdb 101 moleculemonthhepatitisvirusprotease
https://pdb101.rcsb.org/sci-art/goodsell-gallery/bacteriophage-t4-infection
PDB-101: Goodsell Gallery: Bacteriophage T4 Infection
Bacteriophage T4 infects bacterial cells, forcing the cell to create many new bacteriophages.
pdb 101 goodsellgallerybacteriophaget4infection
https://pdb101.rcsb.org/teach/box-of-lessons/topics/biological-macromolecules
PDB-101: Topics
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101topics
https://pdb101.rcsb.org/browse/antimicrobial-resistance
PDB-101: Browse: Antimicrobial Resistance
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 browseantimicrobial resistance
https://pdb101.rcsb.org/sci-art/goodsell-gallery/hiv-infected-cell
PDB-101: Goodsell Gallery: HIV-Infected Cell
Integrative illustration of a cell infected with HIV-1
pdb 101 goodsellhiv infectedgallerycell
https://pdb101.rcsb.org/sci-art/goodsell-gallery/excitatory-and-inhibitory-synapses
PDB-101: Goodsell Gallery: Excitatory and Inhibitory Synapses
Excitatory and Inhibitory Synapses (2018) by David S. Goodsell
pdb 101 goodsellgalleryexcitatoryinhibitorysynapses
https://pdb101.rcsb.org/sci-art/goodsell-gallery/respiratory-droplet
PDB-101: Goodsell Gallery: Respiratory Droplet
SARS-CoV-2 in a respiratory droplet.
pdb 101 goodsellgalleryrespiratorydroplet
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-0288-oxyhemoglobin
PDB-101: Geis Archive: Oxyhemoglobin
Geis illustrates the hemoglobin molecule in its oxygenated state.
pdb 101 geisarchive
https://pdb101.rcsb.org/sci-art/geis-archive/gallery-by-name
PDB-101: Geis Gallery Images by Name
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 geisgallery imagesname
https://pdb101.rcsb.org/train/training-events/csm2
PDB-101: A Deep Dive into Computed Structure Model Exploration at RCSB.org
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101deep divecomputed structuremodelexploration
https://pdb101.rcsb.org/teach/molecular-view-of-hiv-aids
PDB-101: Molecular View of HIV/AIDS
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101hiv aidsmolecularview
https://pdb101.rcsb.org/motm/306
PDB-101: Molecule of the Month: Eastern Equine Encephalitis Virus
Infection by EEEV can cause severe neurological disease
pdb 101 moleculeequine encephalitismontheasternvirus
https://pdb101.rcsb.org/motm/134
PDB-101: Molecule of the Month: Integrin
Integrins forge flexible linkages between the infrastructure inside and outside of cells
pdb 101 moleculemonth
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/rcsb-0002-ribonuclease-s
PDB-101: Geis Archive: Ribonuclease S
pdb 101 geisarchiveribonuclease
https://pdb101.rcsb.org/sci-art/goodsell-gallery/myoglobin-in-a-whale-muscle-cell
PDB-101: Goodsell Gallery: Myoglobin in a Whale Muscle Cell
Cross section through a whale muscle shows the dense packing of myoglobin
pdb 101 goodsellmuscle cellgallerywhale
https://pdb101.rcsb.org/sci-art/geis-archive/gallery/geis-0299-dpg-bound-hemoglobin
PDB-101: Geis Archive: DPG-Hemoglobin Complex
pdb 101 geisarchivedpghemoglobincomplex
https://pdb101.rcsb.org/motm/motm-by-title
PDB-101: Molecule of the Month By Title
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb 101 moleculemonthtitle