https://www.bruker.com/ko/products-and-solutions/microscopes/bioafm/resource-library/single-molecule-dna-overstretching-using-optical-tweezers.html
Understand the utility of optical tweezers for investigating single DNA molecules, especially for probing both DNA and protein-DNA interactions
free pdfsingle moleculeoptical tweezersdnastretching
https://pubmed.ncbi.nlm.nih.gov/24634573/
We present an asymptotic treatment of errors involved in point-based image registration where control point (CP) localization is subject to heteroscedastic...
image registrationanalysispointbasederrors
https://www.imperial.ac.uk/institute-clinical-sciences/research/innovative-imaging-across-scales-network/research/single-molecule-imaging/
Single molecule microscopy approaches established by Rueda (Department of Medicine, Medicine) reveal the structural dynamics of individual molecules,...
imperial college londonsingle moleculeimagingfacultymedicine
https://curie.fr/publications/single-molecule-study-non-specific-binding-kinetics-laci-mammalian-cells
Many key cellular processes are controlled by the association of DNA-binding proteins (DBPs) to specific sites. The kinetics of the search process leading to...
single moleculestudynonspecificbinding
https://www.mdpi.com/1420-3049/23/12/3105
Bacterial periplasmic binding proteins (PBPs) undergo a pronounced ligand-induced conformational change which can be employed to monitor ligand concentrations.
single moleculestudiesfretbiosensorlessons
https://www.timeshighereducation.com/research/sungkyunkwan-university-skku/biophysics-prof-inki-kim-development-metalens-system-single-molecule-detection-real-time
BiophysicsProf. KIM, INKIDr. Aleksandr Barulin
biophysicsprofinkikimdevelopment
https://www.sciencedaily.com/releases/2010/05/100504220042.htm
An experimental demonstration of a quantum calculation has shown that a single molecule can perform operations thousands of times faster than any conventional...
single moleculemolecularcomputationscalculatethousands
https://www.news-medical.net/life-sciences/History-of-Single-Molecule-Experiments.aspx
Single-molecule experiments guide in identifying key factors that determine the behavior of biomolecules.
single moleculehistoryexperiments
https://www.bruker.com/ru/news-and-events/webinars/2020/single-molecule-localization-microscopy--beyond-the-coverslip.html
This webinar discusses the working components and applications of single-molecule localization microscopy (SMLM) with the Vutara system
single moleculelocalizationmicroscopybeyondcoverslip
https://curie.fr/publications/homophilic-interaction-and-deformation-e-cadherin-and-cadherin-7-probed-single-molecule-force
Retrouvez Homophilic interaction and deformation of E-cadherin and cadherin 7 probed by single molecule force spectroscopy. L'Institut Curie est le 1er centre...
homophilicinteractiondeformationcadherin
https://www.bruker.com/zh/products-and-solutions/microscopes/bioafm/resource-library/single-molecule-dna-overstretching-using-optical-tweezers.html
Understand the utility of optical tweezers for investigating single DNA molecules, especially for probing both DNA and protein-DNA interactions
free pdfsingle moleculeoptical tweezersdnastretching
https://www.spacedaily.com/reports/Single_molecule_devices_push_past_silicon_limits_999.html
Tokyo, Japan (SPX) Feb 06, 2026 - As conventional silicon chips approach fundamental scaling limits, researchers are intensifying efforts to build electronic...
single moleculedevicespushpastsilicon
https://www.universiteitleiden.nl/onderzoek/onderzoeksoutput/wiskunde-en-natuurwetenschappen/lion-unraveling-the-mechanism-of-multicopper-oxidases-from-ensemble-to-single-molecule
Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma
unravelingmechanismoxidasesensemblesingle
https://pubmed.ncbi.nlm.nih.gov/27002334/
A majority of facioscapulohumeral muscular dystrophy (FSHD) is caused by contraction of macrosatellite repeats called D4Z4 that are located in the subtelomeric...
human chromosomesingle moleculefillinggap
https://pubmed.ncbi.nlm.nih.gov/37824077/
The polyadenylation of the 3' ends of messenger RNAs is an important regulator of stability and translation. We developed the single-molecule poly(A) tail...
single moleculepolytailsequencingsm
https://www.bruker.com/de/products-and-solutions/fluorescence-microscopy/super-resolution-microscopes/resource-library/webinar-recap-single-molecule-localization-microscopy-beyond-the-coverslip.html
Learn what DNA-PAINT is, how it compares to other SMLM techniques, and the unique advantages it provides for imaging multiple specifically-labeled targets at...
single moleculewebinarrecaplocalizationmicroscopy
https://www.bruker.com/it/news-and-events/webinars/2020/single-molecule-localization-microscopy--beyond-the-coverslip.html
This webinar discusses the working components and applications of single-molecule localization microscopy (SMLM) with the Vutara system
single moleculelocalizationmicroscopybeyondcoverslip
https://www.nist.gov/publications/sem-induced-shrinking-solid-state-nanopores-single-molecule-detection
We have investigated the shrinkage of solid state nanopores by a scanning electron microscope and find the process to be reproducible and dependant beam paramet
solid statesingle moleculeseminducedshrinking
https://www.news-medical.net/news/20170203/Single-molecule-detection-of-proteins-in-single-cells.aspx
We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my...
single moleculedetectionproteinscells
https://www.nist.gov/publications/peg-labeled-nucleotides-and-nanopore-detection-single-molecule-dna-sequencing-synthesis
There is a significant need to accurately sequence single DNA and RNA molecules for personalized medicine.
labeled nucleotidessingle moleculepegnanoporedetection
https://sciencedaily.com/releases/2023/05/230503100051.htm
A research group has succeeded in regulating the flow of single molecules in solution by opening and closing the nanovalve mounted on the nanofluidic device by...
single moleculevalvebreakthroughnanoscalecontrol
https://www.frontiersin.org/journals/synaptic-neuroscience/articles/10.3389/fnsyn.2021.761530/full
The function of the neuronal synapse depends on the dynamics and interactions of individual molecules at the nanoscale. With the development of single-molecu...
light sheetsingle moleculesuper resolutionfrontiersillumination
https://www.ub.edu/in2ub/es/in2ub-international-research-seminar-quantum-molecular-spintronics-based-on-single-molecule-magnets-kondo-effect-single-molecule-memory-and-mof-spintronics/
By Prof. Masahiro Yamashita, Tohoku University, Japan Date: 03/07/2019, 16h Venue: Aula Antiga de Graus (Faculty of Physics) Announcement: Link
international researchseminarquantummolecularspintronics
https://www.bruker.com/ko/products-and-solutions/fluorescence-microscopy/super-resolution-microscopes/single-molecule-fish-smfish-rna-visualization-and-quantification.html
Image and quantify RNA with single-molecule sensitivity
single moleculernavisualizationquantificationfish
https://www.universiteitleiden.nl/onderzoek/onderzoeksoutput/wiskunde-en-natuurwetenschappen/plasmonic-enhancement-of-one-photon--and-two-photon-excited-single-molecule-fluorescence-by-single-gold-nanorods
This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs)...
plasmonicenhancementonephotontwo
https://pubmed.ncbi.nlm.nih.gov/38862989/?dopt=Abstract
The extracellular serum ratio of pT73-Rab10 to total Rab10 is a novel pharmacodynamic biomarker for LRRK2-linked innate immune activation associated with...
single moleculearraymeasureskinaseactivity
https://www.nist.gov/publications/theory-polymer-analysis-using-nanopore-based-single-molecule-mass-spectrometry
Nanometer-scale pores have demonstrated potential as a tool for the electrical detection and characterization of molecules.
polymer analysissingle moleculetheoryusingnanopore
https://www.bruker.com/it/products-and-solutions/fluorescence-microscopy/super-resolution-microscopes/smlm-protocols.html
Standard procedures and protocols for single-molecule localization microscopy (SMLM), provided by Bruker super-resolution microscopy applications experts
single moleculelocalizationmicroscopyprotocolsbruker
https://www.psu.edu/news/huck-institutes-life-sciences/story/optical-tweezers-help-elevate-single-molecule-research-penn
Research Professor Neela Yennawar was awarded a $750,000 grant from the National Institutes of Health to support the acquisition of a Lumicks C-Trap optical...
optical tweezerssingle moleculepenn statehelpelevate
https://www.technologynetworks.com/cancer-research/news/double-act-how-a-single-molecule-can-attract-and-repel-growing-brain-connections-192765
The 3D structure of Netrin-1 bound to DCC shows Netrin-1 binds to two DCC molecules in different ways.
double actsingle moleculeattractrepel
https://elifesciences.org/articles/17667
Live-cell single-molecule tracking reveals that hierarchical cooperation within the Polycomb Cbx7 protein between the low-affinity H3K27me3-binding module and...
single moleculelivecelltrackingreveals
https://elifesciences.org/articles/01008
New insights into the mechanism responsible for the nucleation of branches on networks of actin filaments shed light on a process that is essential for...
single moleculethreecolorimagingshows
https://www.ukessays.com/essays/chemistry/single-molecule-magnets-single-chain-magnets-8590.php
The structures and magnetic properties: molecular nanomagnets phenolic oxime complexes GUAN Shengyang Table of Contents (Jump to) 1 Introduction 1.1 Research...
single molecule magnetschain analysiscom
https://www.rug.nl/research/zernike/news/seminars/neuweiler?lang=en
ABSTRACT Proteins are the most important carriers of function in life. As linear chains of amino acids they either remain intrinsically disordered or...
one nanometersingle moleculedrhannesneuweiler
https://www.bruker.com/zh/products-and-solutions/fluorescence-microscopy/super-resolution-microscopes/single-molecule-fish-smfish-rna-visualization-and-quantification.html
Image and quantify RNA with single-molecule sensitivity
single moleculernavisualizationquantificationfish
https://www.mdpi.com/2076-3417/11/3/1066
There is a worldwide race to convert waste heat to useful energy using thermoelectric materials. Molecules are attractive candidates for thermoelectricity...
thermal conductanceeffectanchorgroupphonon