Robuta

https://elifesciences.org/reviewed-preprints/89814
computational engineeringtherapeutic antibodyinhibitmultiplemutants
https://www.ncbi.nlm.nih.gov/Structure/pdb/4LAS
Single chain antibody fragment scFv6H44-[(2S)-2-(methylamino)propyl]phenol
crystal structuresingle chaintherapeuticantibody
https://pubmed.ncbi.nlm.nih.gov/23486779/
The Wilms tumor 1 (WT1) oncoprotein is an intracellular, oncogenic transcription factor that is overexpressed in a wide range of leukemias and solid cancers....
targetingintracellularoncogeneproducttherapeutic
https://www.yumab.com/
YUMAB is a world leading provider of contract research, technologies, and R&D services for the development of fully human, therapeutic antibodies.
therapeutic antibodydiscoverydevelopment
https://www.ncbi.nlm.nih.gov/Structure/pdb/8SO3
Lymphocyte activation gene 3 proteinfavezelimab Fab heavy chainfavezelimab Fab light chain2-acetamido-2-deoxy-beta-D-glucopyranose
therapeutic antibodycryoemstructurefavezelimabbound
https://www.aip.org/scilights/protein-engineering-strategies-contribute-efficient-production-of-therapeutic-antibody-fragments
Advances in production methods make antibody fragments a valuable tool in therapeutic applications.
protein engineeringtherapeutic antibodystrategiescontributeefficient
https://www.fda.gov/science-research/licensing-and-collaboration-opportunities/therapeutic-and-prophylactic-anti-influenza-virus-neuraminidase-1-n1-antibody-cd6-novel-epitope
CD6 is a potent monoclonal antibody against N1 subtypes of NA that inhibits the enzymatic activity of the NA protein, including NA variants resistant to NA...
influenza virustherapeuticprophylacticantineuraminidase
https://www.news-medical.net/news/20230301/Antiverse-raises-funding-and-demonstrates-therapeutic-antibody-identification-with-AI-driven-drug-discovery-platform.aspx
Antiverse Ltd (Antiverse), a biotechnology company developing a computational antibody drug discovery platform, today announced the successful identification...
therapeutic antibodyantiverseraisesfundingidentification
https://www.sigmaaldrich.com/HU/en/integrated-offerings/monoclonal-antibodies/antibody-drug-discovery/target-discovery
Identify novel targets for therapeutic antibody development using the most comprehensive set of genome-wide functional genomics screening tools available.
therapeutic antibodytarget discovery
https://pubmed.ncbi.nlm.nih.gov/31544850/
Phage display technology has played a key role in the remarkable progress of discovering and optimizing antibodies for diverse applications, particularly...
phage displaylibrariesantibodytherapeuticdiscovery
https://informaconnect.com/bispecifics-asia/speakers/shohei-koide-phd/
Speaker profile for Shohei Koide, PhD
new york universityshoheikoidephdschool
https://pubmed.ncbi.nlm.nih.gov/26390038/
CD47 is a widely expressed cell surface protein that functions as a regulator of phagocytosis mediated by cells of the innate immune system, such as...
pre clinical developmenthumanizedanti
https://pubmed.ncbi.nlm.nih.gov/26379667/
Specific antibodies against infections most relevant to patients with primary immunodeficiency diseases are not routinely evaluated in commercial polyclonal...
antibody titertherapeuticimmunoglobulinselectedhigh
https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2023.1117844/full
The rise of antimicrobial-resistant bacterial infections is a crucial health concern in the 21st century. In particular, antibiotic-resistant Pseudomonas aer...
pseudomonas aeruginosamonoclonal antibodyfrontiersdevelopmenttherapeutic
https://www.jci.org/articles/view/30446/figure/3
jcitherapeuticantiegfrresponses