Robuta

https://www.mdpi.com/1999-4915/16/10/1509 Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for... Triggering receptor expressed on myeloid cells 2 (TREM2) is involved in neuroinflammation and HIV-associated neurocognitive impairment (NCI). https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1462508/full Frontiers | The various roles of TREM2 in cardiovascular disease Triggering receptor expressed on myeloid cells-2 (TREM2) is a transmembrane immune receptor that is expressed mainly on macrophages. As a pathology-induced i... the variousin cardiovascularfrontiersrolestrem2 https://www.jax.org/strain/031942 031942 - Snx1*D465N/APOE4/Trem2*R47H Strain Details snx1apoe4trem2straindetails https://pmc.ncbi.nlm.nih.gov/articles/PMC9481739/ Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia - PMC Using mouse models overexpressing human TREM2 in microglia, this study shows that WT TREM2 expression reduces amyloid deposition and suppresses... elevatingmicrogliatrem2reducesamyloid https://elifesciences.org/articles/20391 Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct... Structural, biophysical, and functional analyses reveal that mutations in TREM2 trigger either misfolding or reduced binding to cell-surface... neurodegenerative diseasemutationstrem2 https://www.jci.org/articles/view/135197/pdf JCI - TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver... jcitrem2sustainsmacrophagehepatocyte https://www.jax.org/strain/031880 031880 - BAC-TREM2 Strain Details bactrem2straindetails https://www.jax.org/strain/029853 029853 - Trem2 flox Strain Details trem2floxstraindetails