https://pubmed.ncbi.nlm.nih.gov/25532521/
Macrophage multinucleation (MM) is essential for various biological processes such as osteoclast-mediated bone resorption and multinucleated giant...
integratingtranscriptomerevealsnewdeterminants
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.880887/full
Macrophages are paracrine signalers that regulate tissular responses to injury through interactions with parenchymal cells. Connexin hemichannels have recent...
frontiersmacrophagenecessaryfibroblastcytosolic
https://xylonix.io/
Solutions to post-COVID dysfunctional macrophage immunity problems: Turbo Cancers, autoimmune disorders, long COVID, Infectious diseases, and Disease X.
innovationsbettermacrophageimmunity
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.624746/full
Mesenchymal stem cells (MSCs) are multipotent adult stromal cells widely studied for their regenerative and immunomodulatory properties. They are capable of ...
mesenchymal stem cellfrontiersmacrophageresponsedriven
https://pierre-francois-roux.com/publication/impaired-function-of-macrophage-from-cystic-fibrosis-patients-cd11b-tlr-5-decrease-and-scd24-inflammatory-cytokines-increase/
Early in life, cystic fibrosis (CF) patients are infected with microorganisms. The role of macrophages has largely been underestimated in literature, whereas...
cystic fibrosisimpairedfunctionmacrophagepatients
https://pubmed.ncbi.nlm.nih.gov/29266506/
Increased mid-pregnancy CCL4 levels showed borderline associations with increased offspring T1D risk, which may indicate a link between environmental factors...
cord bloodplasmaimmunologicalmarkerspregnancy
https://www.academia.edu/11503791/IL_17_mediated_M1_M2_Macrophage_Alteration_Contributes_to_Pathogenesis_of_Bisphosphonate_related_Osteonecrosis_of_the_Jaws
Nov 28, 2024 - Purpose: Osteonecrosis of the jaw (ONJ) is emerging as one of the important complications in cancer patients treated with antiresorptive agents. This study...
pdfilmediatedmacrophagealteration
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.00533/full
Mycobacterium tuberculosis can proficiently enter phagocytes and diminish complement activation on its cell surface. Within phagocytes, the mycobacterium can...
mycobacterium bovisfrontiershumanproperdinmacrophage
https://www.mdpi.com/2079-4983/14/6/319
Piperine (PIP), a compound found in Piper longum, has shown promise as a potential chemotherapeutic agent for breast cancer. However, its inherent toxicity has...
cell membranemacrophagecoatingpiperineloaded
https://pubmed.ncbi.nlm.nih.gov/27130185/
Foxp3(+) regulatory T (Treg) cells play a pivotal role in maintaining immunological tolerance. Loss-of-function mutations in the Foxp3 gene result in...
monocytemacrophagelineagecommitmentdistribution
https://pubmed.ncbi.nlm.nih.gov/11775265/
IL-2 and IL-6 gene therapy can relieve the suppression of macrophages of the lymphoma-bearing mice, and efficiently activate the antitumor immune responses.
macrophage activationlymphomabearingmiceliposome
https://pubmed.ncbi.nlm.nih.gov/30131066/
Our results suggest a prominent role of neuroinflammation in BIPN and that IVIg might be considered as a possible safe and effective therapeutic option...
intravenous immunoglobulinshighdosereducenerve
https://sciencedaily.com/releases/2024/05/240521124259.htm
A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to new...
immune cellsdrughelpsreprogrammacrophage
https://www.rcsb.org/structure/8IMR
Structure of ligand-free human macrophage migration inhibitory factor
rcsbpdbstructureligandfree
https://www.sigmaaldrich.com/US/en/tech-docs/paper/1535101
Macrophage's proinflammatory response to a mycobacterial infection is dependent on sphingosine kinase-mediated activation of phosphatidylinositol phospholipase...
macrophageproinflammatoryresponsemycobacterialinfection
https://www.biophact.fr/a-newly-identified-macrophage-manager-zeb2-2/
A newly identified macrophage manager ZEB2: still known as pivotal in early fetal development and cancer progression by driving the epithelial-to-mesenchymal...
newlyidentifiedmacrophagemanager
https://pubmed.ncbi.nlm.nih.gov/17443469/
MIF is markedly and persistently up-regulated in children and adults with gram-negative sepsis and is associated with parameters of disease severity, with...
associationhighlevelsbloodmacrophage
https://www.usgs.gov/publications/utility-splenic-macrophage-aggregates-indicator-fish-exposure-degraded-environments
The utility of splenic macrophage aggregates (MAs) as an indicator of fish exposure to degraded environments was evaluated in several species of estuarine...
utilitysplenicmacrophageaggregatesindicator
https://pubmed.ncbi.nlm.nih.gov/22105735/
In most mammalian species, the removal of one lung results in dramatic compensatory growth of the remaining lung. To investigate the contribution of alveolar...
alveolar macrophagedynamicsmurinelungregeneration
https://pubmed.ncbi.nlm.nih.gov/28859549/
Traumatic brain injury (TBI) induces widespread neuroinflammation and accumulation of microtubule associated protein tau (MAPT): two key pathological features...
traumatic brain injurymodelmiceenhancedacute
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2020.00569/full
Endothelial cell derived angiocrine factors contribute to the disruption of homeostasis and the pathogenesis of cardiovascular diseases in response to stress...
frontiersstimulatesendothelialderivedalarmin
https://www.technologynetworks.com/cell-science/news/new-regulators-of-macrophage-pyroptosis-313032
Two enzymes, TAK1 and IKK, have been identified as important kinases involved in the regulation of pyroptosis - a highly inflammatory form of programmed cell...
newregulatorsmacrophagepyroptosistechnology