adisinsight - Robuta Search

https://adisinsight.springer.com/drugsafety/803928593?error=cookies_not_supported&code=56613a2b-f79e-47b7-8021-cfde8d763b64 Elexacaftor/ivacaftor/tezacaftor - AdisInsight Eleven patients [age and sex not stated] with cystic fibrosis in France were treated with elexacaftor-tezacaftor-ivacaftor and were reported as requiring lung adisinsight https://adisinsight.springer.com/trials/700391604?error=cookies_not_supported&code=5e9b75f4-0e8e-482a-ac5f-21c8d84f106c A Phase 1b/2 study of CX-2051 in combination with bevacizumab and chemotherapy - AdisInsight A Phase 1b/2 study of CX-2051 in combination with bevacizumab and chemotherapy https://adisinsight.springer.com/drugsafety/803861770?error=cookies_not_supported&code=d51233be-b980-4a71-9f8b-dd398a589f8d Apixaban/heparin/warfarin - AdisInsight A male patient [age at reaction onset not stated] developed drug-induced thrombocytopenia during treatment with heparin for thrombosis. Additionally, he apixaban heparin warfarin adisinsight https://adisinsight.springer.com/drugsafety/803929325?error=cookies_not_supported&code=e5a637ae-0b3d-44d3-ad03-4bc25a4a81ed Thioctic acid - AdisInsight An 83-year-old Caucasian woman with hypertension and type 2 diabetes experienced nephrotic-range proteinuria, hypoalbuminaemia and NELL1-associated membranous acid adisinsight https://adisinsight.springer.com/drugsafety/803860222?error=cookies_not_supported&code=8c31821e-f9a1-483c-9b26-34ac164c4e94 Prednisone - AdisInsight In a retrospective study of 6 patients, a 51-year-old man was described, who developed central obesity during treatment with prednisone for acquired haemophilia prednisone adisinsight https://adisinsight.springer.com/drugsafety/803238459?error=cookies_not_supported&code=805f753c-8cb3-4f23-abea-204ce3b1e8b5 Tamsulosin - AdisInsight An 81-year old man developed angle-closure glaucoma and intraoperative floppy iris syndrome (IFIS) following treatment with tamsulosin [dosage and indication tamsulosin adisinsight https://adisinsight.springer.com/drugsafety/803775031?error=cookies_not_supported&code=bb94670e-8488-467e-aeef-3234b6d0040d Frequency of drug-induced anaphylaxis and fatal anaphylaxis in Japan - AdisInsight The frequency of drug-induced anaphylaxis (AN) changed little over a 13-year period in Japan, according to findings of a study published in Allergology in japan frequency drug induced anaphylaxis https://adisinsight.springer.com/drugsafety/803524778?error=cookies_not_supported&code=ed795e75-63bd-4775-a5a4-1d4fa08302af Adalimumab - AdisInsight A 30-year-old woman developed neutropenia with reactivation of Cytomegalovirus and Epstein-Barr virus during treatment with adalimumab for Crohn's disease adalimumab adisinsight https://adisinsight.springer.com/drugsafety/801121322?error=cookies_not_supported&code=1a5bd9ba-3dcf-4d8f-847f-3e092f4374bc Mirtazapine - AdisInsight Two patients with symptoms of depression developed profound hyponatraemia shortly after starting mirtazapine.While in hospital with newly diagnosed subacute mirtazapine adisinsight https://adisinsight.springer.com/drugsafety/803923768?error=cookies_not_supported&code=fc8b64bd-3fa1-4e68-a823-ecf8ace4b065 Zoledronic acid - AdisInsight A 64-year-old woman developed preseptal and orbital inflammation following intravenous zoledronate for osteoporosis. The woman received intravenous zoledronate zoledronic acid adisinsight https://adisinsight.springer.com/drugsafety/803909762?error=cookies_not_supported&code=99e8da18-8bab-4b35-b85f-aca6052d5fde Miglustat - AdisInsight Two female siblings, aged 13 and 10 years, with genetically confirmed CLN3 disease (homozygous for the common 1 kb deletion), were treated with oral, adisinsight https://adisinsight.springer.com/trials/700299162?error=cookies_not_supported&code=63f63e54-f9c9-46cf-850a-076331578ec4 A clinical study of PRO 140 for the treatment of colon carcinoma patients - AdisInsight This is a clinical study of PRO 140 for the treatment of colon carcinoma patients. https://adisinsight.springer.com/drugsafety/803295037?error=cookies_not_supported&code=65306337-9a92-492f-ac1e-ca92914f557e Oxacillin - AdisInsight A 53-year-old woman developed DRESS syndrome during treatment with oxacillin [Oxacillin] [route not stated].The woman was started on oxacillin 100 mg/kg/day and adisinsight https://adisinsight.springer.com/drugsafety/803658841?error=cookies_not_supported&code=c9574b95-4da9-48d3-9d36-e2875fd6b444 Methylprednisolone - AdisInsight A 19-year-old woman developed rebound eosinophilic inflammation following discontinuation of methylprednisolone.The woman, who had cystic fibrosis, presented to methylprednisolone adisinsight https://adisinsight.springer.com/drugsafety/803637617?error=cookies_not_supported&code=1c65511e-6fe1-4903-ae92-f1bf362fe9f8 Imatinib - AdisInsight A man in his 20s [exact age at reaction onset not stated] developed myelotoxicity during treatment with imatinib for dermatofibrosarcoma protuberans.The man was imatinib adisinsight https://adisinsight.springer.com/drugsafety/803750345?error=cookies_not_supported&code=c5e9e887-ee1f-4cdd-beec-5f0fd83803c2 Betamethasone/teriparatide - AdisInsight A 26-year-old woman received betamethasone and off label treatment with teriparatide during pregnancy for autosomal dominant hypoparathyroidism (ADH) [not all betamethasone teriparatide adisinsight https://adisinsight.springer.com/drugsafety/803524068?error=cookies_not_supported&code=292b37a6-3791-477c-861f-6606990bb00a Rifampicin - AdisInsight A 45-year-old man developed lichenoid drug eruption (LDE) during treatment with rifampicin for pulmonary tuberculosis.The man, who was diagnosed with rifampicin adisinsight https://adisinsight.springer.com/drugsafety/803735629?error=cookies_not_supported&code=84ba55ce-2c92-45e1-a293-313882f759f2 Amiodarone/ascorbic acid - AdisInsight In a case series, a 70-year-old man and a 80-year-old woman were described, who developed acute tubular injury during treatment with amiodarone or ascorbic acid ascorbic acid amiodarone adisinsight https://adisinsight.springer.com/drugsafety/803923427?error=cookies_not_supported&code=a3519a44-3bcc-4992-9dfd-48a257c62be3 GLP-1 receptor agonist-related psychiatric AEs - AdisInsight Use of the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide for weight loss may cause psychiatric adverse events (AEs), according to findings of a glp receptor agonist related psychiatric https://adisinsight.springer.com/drugsafety/803374667?error=cookies_not_supported&code=72a68977-06f6-499c-8d51-140478246c8a Cisplatin/gimeracil/oteracil/tegafur - AdisInsight A 71-year-old man developed anorexia and elevated ALP level during treatment with cisplatin and gimeracil/oteracil/tegafur [S-1] for an advanced gastric cisplatin adisinsight https://adisinsight.springer.com/drugsafety/803897772?error=cookies_not_supported&code=0d930855-fcc1-4a14-aca7-d7a09a09a271 Caspofungin/Isavuconazole/Mycophenolate-mofetil/Tacrolimus - AdisInsight A man in his 60's [exact age not stated] developed invasive fungal rhinosinusitis due to Aspergillus fumigatus during treatment with tacrolimus and mycophenolate mofetil caspofungin tacrolimus adisinsight https://adisinsight.springer.com/drugs/800086291?error=cookies_not_supported&code=b24f6017-7e64-46ea-bb09-ca664db5a440 Meloxicam injection - Nanjing Delova Biotech - AdisInsight QP 001 is an intravenous, 24 hours long acting, single dose formulation of meloxicam being developed by Nanjing Delova Biotech for the treatment of meloxicam injection nanjing biotech adisinsight https://adisinsight.springer.com/drugsafety/803881570?error=cookies_not_supported&code=89082df4-5c96-4b3f-8f3c-ba3bbc3f73be Multiple drugs - AdisInsight In a case series, 4 patients aged 36-65 years (2 men and 2 women) were described, who developed changes in urine color, moderately severe sensorineural hearing multiple drugs adisinsight https://adisinsight.springer.com/drugsafety/803496275?error=cookies_not_supported&code=a03918d2-f5aa-4807-b120-fe847b5404c3 Antineoplastics - AdisInsight A woman in her late 50s developed pancytopenia during treatment with dexamethasone, vincristine, daunorubicin and pegaspargase for acute leukemia. The woman had antineoplastics adisinsight https://adisinsight.springer.com/drugs/800086902?error=cookies_not_supported&code=9a31a4d8-73fd-43f6-8472-d0142442eafb Research programme: chronic heart failure therapeutic - Spur Therapeutics - AdisInsight Gene therapy is being developed by Spur Therapeutics for the treatment of chronic heart failure. Early research is ongoing in the United Kingdom. chronic heart failure research programme spur therapeutics adisinsight https://adisinsight.springer.com/drugsafety/803374911?error=cookies_not_supported&code=e67a02a0-1d2f-49ca-b42b-6cd399d497f2 Iohexol - AdisInsight A 36-year-old man developed delayed hyperdense ascites following administration of oral iohexol for CT scan examination.The man, who had medical history of iohexol adisinsight https://adis.springer.com/?error=cookies_not_supported&code=d15eab64-95d7-48e1-996f-ad7655b3fc9f Home - AdisInsight adisinsight https://adisinsight.springer.com/patents/800048399 Phenylephrine/tropicamide - Eyenovia - AdisInsight phenylephrine tropicamide adisinsight https://adisinsight.springer.com/drugsafety/803683211?error=cookies_not_supported&code=c1619b0a-a3e1-4fbc-90f3-9e33bcdf5284 Voretigene-neparvovec - AdisInsight In a study involving five patients with early onset retinal degeneration (EORD), a 36-year-old woman (P4, identified from Figure 2) was described, who exhibited adisinsight https://adisinsight.springer.com/drugsafety/803575776?error=cookies_not_supported&code=490dde37-0e5f-4b38-b293-4b4ae53f2bc2 Trametinib - AdisInsight A 28-year-old man developed acneiform rash, paronychia and asthenia during an off-label treatment with trametinib for agminated benign vascular tumour.The man trametinib adisinsight https://adisinsight.springer.com/drugsafety/800412825?error=cookies_not_supported&code=693401fa-0f78-4985-8ce4-121c48e69fb0 Chlorambucil - AdisInsight chlorambucil adisinsight https://adisinsight.springer.com/drugsafety/803536248?error=cookies_not_supported&code=9f6f4a54-e093-4045-b92f-980eac6b139f Doxorubicin/prednisone - AdisInsight A 53-year-old man developed elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) during treatment with doxorubicin for sarcoma doxorubicin prednisone adisinsight https://adisinsight.springer.com/drugsafety/803929470?error=cookies_not_supported&code=bfc26cd4-e3bf-419b-8c9f-58ce77fcca90 Citric-acid/glucose/monosodium-phosphate/sodium-citrate - AdisInsight A 48-year-old man with hypertension and end-stage renal disease due to focal segmental glomerulosclerosis, status post kidney transplantation 21 years earlier, citric acid monosodium phosphate glucose citrate adisinsight https://adisinsight.springer.com/drugsafety/800173264?error=cookies_not_supported&code=16007fcc-8881-4d00-bac6-4a7f3f7ea991 BCG - AdisInsight Nausea, vomiting and confusion prompted the hospitalisation of a 66-year-old man after his first monthly intravesical instillation of BCG (Tice strain) to treat bcg adisinsight https://adisinsight.springer.com/drugsafety/803119165?error=cookies_not_supported&code=55479734-b090-48cc-9800-7393d8694eb8 Sunitinib - AdisInsight In a retrospective study of 155 patients, aged 18 years or older, 1 patient [age and sex not stated] was identified to have developed nephrotic syndrome during sunitinib adisinsight https://adisinsight.springer.com/drugsafety/803080344?error=cookies_not_supported&code=ee78e141-0f52-4425-8b35-090f6f218c2b Nadroparin calcium - AdisInsight A 46-year-old woman experienced an immediate hypersensitivity reaction after receiving nadroparin calcium [Fraxiparine].The woman, who had a history of calcium adisinsight https://adisinsight.springer.com/drugsafety/803076528?error=cookies_not_supported&code=193aa3a0-57a4-485f-8749-301b2cdb046a Gadopentetic acid/gadoteridol - AdisInsight Two girls developed hypersensitivity after receiving gadopentetic acid or gadoteridol for MRI procedures [routes and dosages not stated].A 17-year-old girl, acid adisinsight https://adisinsight.springer.com/drugsafety/803064883?error=cookies_not_supported&code=3d706913-8736-4d70-9fcd-e4d83c9110be Methylprednisolone - AdisInsight A 15-year-old girl developed atrial fibrillation (AF) while receiving methylprednisolone.The girl had been diagnosed with lupus nephritis in 2007, and had methylprednisolone adisinsight https://adisinsight.springer.com/drugsafety/803181991?error=cookies_not_supported&code=c8646d1a-5113-432a-8ebe-eaabe202ed58 Pembrolizumab - AdisInsight A 51-year-old woman developed eosinophilic fasciitis following treatment with pembrolizumab. The woman received treatment with pembrolizumab, as a first-line pembrolizumab adisinsight https://adisinsight.springer.com/drugsafety/803179204?error=cookies_not_supported&code=8cf9df30-e089-4ce4-acb9-c74dc50c0f14 Febuxostat may increase risk of heart failure - AdisInsight After conducting a safety review, Health Canada is advising that treatment with febuxostat (Uloric) in patients with gout may increase the risk of heart heart failure febuxostat may increase risk https://adisinsight.springer.com/drugsafety/803924913?error=cookies_not_supported&code=31788245-d069-48bc-927a-e8eaf753121e Iomeprol/Ioversol - AdisInsight A 79-year-old man with a ruptured thoracic aortic aneurysm developed contrast-induced encephalopathy after receiving iomeprol and ioversol during thoracic ioversol adisinsight https://adisinsight.springer.com/drugsafety/803906309?error=cookies_not_supported&code=8ac1d228-bed0-4e3b-ab68-6df8cd96c719 Brexucabtagene-autoleucel/Tisagenlecleucel - AdisInsight In a multi-center observational study of 173 patients with haematologic malignancies, concluded until the end of June 2024 in Greece, two adults patients [sexes tisagenlecleucel adisinsight https://adisinsight.springer.com/drugsafety/800503007?error=cookies_not_supported&code=47dd3374-a9a0-4f44-a7ff-5350e7abfa6b Cisplatin - AdisInsight Two boys, 2 men and a woman, aged 6-57 years with disseminated (n = 1) or posterior fossa (1) medulloblastoma, metastatic renal cell cancer (1) or glioblastoma cisplatin adisinsight https://adisinsight.springer.com/drugs/800046654?error=cookies_not_supported&code=4d10783b-5694-4803-9381-b153fca80502 Research programme: protozoan infection therapeutics - Synstar Japan - AdisInsight Synstar Japan is developing compounds for the treatment of African trypanosomiasis, Chagas disease and Leishmaniasis. Development is at the lead optimisation research programme protozoan infection therapeutics japan https://adisinsight.springer.com/drugs/800086345?error=cookies_not_supported&code=fe13c9b4-fb6d-492a-b7ff-a233eb9c6856 MAX 20492 - AdisInsight MAX 20492 is a diagnostic imaging reagent targeting programmed death ligand 1 (PD L1) being developed by Maxinovel for the diagnosis of cancer. Clinical max adisinsight https://adisinsight.springer.com/drugsafety/803927311?error=cookies_not_supported&code=5c81c5ce-570f-4614-bce5-8e04e6063eda Isavuconazole - AdisInsight A 14-year-old boy with pulmonary aspergillosis received isavuconazole, used off-label due to his paediatric age, and experienced supratherapeutic exposure. The adisinsight https://adisinsight.springer.com/drugsafety/803073267?error=cookies_not_supported&code=415b23fe-f105-45e1-b081-a3564ca82363 Immunosuppressants/rituximab - AdisInsight In a retrospective review of the French Autoimmunity and Rituximab registry, three patients with systemic rheumatoid vasculitis were identified after they immunosuppressants rituximab adisinsight https://adisinsight.springer.com/drugsafety/803779123?error=cookies_not_supported&code=96ed1714-5594-44f6-90e2-a77ac203377d Acarbose/octreotide - AdisInsight A 50-year-old woman developed gastrointestinal side effects during treatment with acarbose while relentless constipation during treatment with octreotide acarbose octreotide adisinsight https://adisinsight.springer.com/drugsafety/803356214?error=cookies_not_supported&code=0ce194a6-9047-4954-910c-0b614ef8df24 Hydroxocobalamin - AdisInsight A 26-year-old man experienced lack of efficacy during treatment with hydroxocobalamin [route not stated] for cardiopulmonary arrest.The man presented 12 hours hydroxocobalamin adisinsight https://adisinsight.springer.com/drugsafety/803563466?error=cookies_not_supported&code=97fa4e57-7c49-483e-a84f-14736f3dce4e Amiodarone - AdisInsight A 48-year-old man experienced exacerbation of hyperthyroidism while receiving amiodarone for ventricular fibrillation.The man found in out of hospital with amiodarone adisinsight https://adisinsight.springer.com/drugsafety/803579972?error=cookies_not_supported&code=0da06901-9e9b-4482-b26c-d8f97f96fdc3 Methotrexate - AdisInsight In a retrospective cohort study, two women [ages not stated] were described, who exhibited treatment failure during treatment withmethotrexate for cesarean scar methotrexate adisinsight https://adisinsight.springer.com/drugsafety/803878036?error=cookies_not_supported&code=67699e32-3905-4683-93d8-b04514f78d8c Methotrexate/Mycophenolate-mofetil - AdisInsight A 46-year-old woman developed gastrointestinal intolerance during treatment with methotrexate and mycophenolate-mofetil for Behcet's syndrome (BS) [routes, mycophenolate mofetil methotrexate adisinsight https://adisinsight.springer.com/drugs/800039341?error=cookies_not_supported&code=cb7b376e-f386-47aa-b9d0-6106bb1eff10 Livoletide - Tempest Therapeutics - AdisInsight Llivoletide (AZP 531) was an analogue of unacylated ghrelin or des-n-octanoyl ghrelin, being developed by Millendo Therapeutics (now Tempest Therapeutics) for tempest therapeutics adisinsight https://adisinsight.springer.com/patents/800025994 Paracetamol intravenous - Bristol-Myers Squibb/Mallinckrodt - AdisInsight bristol myers squibb paracetamol intravenous mallinckrodt adisinsight https://adisinsight.springer.com/drugs/800031292?error=cookies_not_supported&code=648e7698-612e-46f1-9b43-2ddb2f89aba4 Research programme: vaccines - Sinovac (Dalian) Vaccine Technology - AdisInsight Sinovac (Dalian) Vaccine Technology is a joint venture company established by Sinovac Biotech and Dalian Jin Gang Group, to research, develop, manufacture and research programme vaccine technology vaccines sinovac dalian https://adisinsight.springer.com/drugsafety/803432348?error=cookies_not_supported&code=41317114-7f52-42bf-8205-7d1cc4248d67 Acarbose/liraglutide - AdisInsight A woman [age not stated] exhibited no improvement during treatment with acarbose and liraglutide for hypoglycaemia related to Roux-en-Y Gastric Bypass (RYGB). acarbose liraglutide adisinsight https://adisinsight.springer.com/drugsafety/803542392?error=cookies_not_supported&code=6abd6362-70ae-40a7-b33d-ff705af9ebdf Aspirin/clopidogrel/heparin - AdisInsight In a non-randomised, single-center retrospective study of 539 patients who underwent coil embolisation from July 2014 to August 2019, 8 patients including one aspirin clopidogrel heparin adisinsight https://adisinsight.springer.com/drugsafety/803004700?error=cookies_not_supported&code=38c3b41d-4898-4004-9312-43986c1e2b9c Antituberculars - AdisInsight A 55-year-old woman developed DRESS syndrome during treatment with rifampicin, isoniazid, pyrazinamide and ethambutol [dosages and durations of therapies to adisinsight https://adisinsight.springer.com/drugsafety/803929857?error=cookies_not_supported&code=f46c1d9c-c08a-44a7-8ffe-21d91ac09ba0 Plasma - AdisInsight A 45-year-old nulligravid woman with uterine fibroids and ovarian cysts underwent intraovarian platelet-rich plasma injections [dose and treatment duration not plasma adisinsight https://adisinsight.springer.com/drugs/800053090?error=cookies_not_supported&code=968bf61d-6e9d-4270-a3eb-3698b2be8a12 Fol PRI 002 - AdisInsight Fol PRI 002 is a folic acid prodrug of PRI 002, being developed by Priavoid, for the treatment of Alzheimer's disease. PRI 002 [see Adis Insight Drug profile fol pri adisinsight https://adisinsight.springer.com/drugsafety/803115861?error=cookies_not_supported&code=bb3ba17f-3933-43aa-82d9-ab77d5c3d063 Metformin overdose - AdisInsight From a study, a woman [age not stated] was identified who developed lactic acidosis following an overdose of metformin. The woman presented with self-induced metformin overdose adisinsight https://adisinsight.springer.com/drugsafety/803926847?error=cookies_not_supported&code=29aa6c8b-72a2-4125-bcef-2c643b248b59 Vaccines - AdisInsight Five patients developed persistent shoulder pain and dysfunction consistent with Shoulder Injury Related to Vaccine Administration following administration of a vaccines adisinsight https://adisinsight.springer.com/drugsafety/800005861?error=cookies_not_supported&code=281bf838-74f4-4dda-a7e9-675efa1d91b5 Clomipramine - AdisInsight clomipramine adisinsight https://adisinsight.springer.com/patents/800010198 Anti-digoxin polyclonal antibody - AMAG Pharmaceuticals/Glenveigh Pharmaceuticals - AdisInsight polyclonal antibody digoxin amag pharmaceuticals adisinsight https://adisinsight.springer.com/drugsafety/803225257?error=cookies_not_supported&code=9039f8ba-02cc-49ba-89eb-af8d430d6236 Antipsychotics - AdisInsight A 14-year-old boy developed raise in the liver function tests during treatment with atomoxetine and other unspecified psychotropics [dosage, route, duration of antipsychotics adisinsight https://adisinsight.springer.com/drugsafety/803929030?error=cookies_not_supported&code=10d84a21-d4d3-413a-8679-1e67f7ca7d7f Vascular endothelial growth factors inhibitors - AdisInsight Nineteen patients [age and sex not stated] with macular oedema secondary to retinal vein occlusion experienced lack of efficacy due to intravitreal anti-VEGF growth factors vascular endothelial inhibitors adisinsight https://adisinsight.springer.com/drugsafety/803137966?error=cookies_not_supported&code=e1fea41c-96fc-4024-b609-264c69a4ac46 Ethambutol/pyrazinamide - AdisInsight A 26-year-old man developed polyarthralgia and myopathy following administration of pyrazinamide and ethambutol.The man who was diagnosed with pulmonary ethambutol pyrazinamide adisinsight https://adisinsight.springer.com/drugsafety/803924884?error=cookies_not_supported&code=66202f34-13eb-4047-a9c2-71ba44dcfd79 Carboplatin/Paclitaxel/Pembrolizumab - AdisInsight A 66-year-old man with stage IVB squamous cell carcinoma of the left upper lung and hepatic metastasis experienced lack of efficacy during treatment with carboplatin paclitaxel pembrolizumab adisinsight https://adisinsight.springer.com/drugsafety/803895682?error=cookies_not_supported&code=001a3be6-dea7-4846-9b35-f269342fd1dd Amitriptyline/mirogabalin/oxycodone - AdisInsight A 52-year-old man developed serotonin syndrome following combination treatment (drug-drug pharmacokinetic interaction) of oxycodone and amitriptyline (drug-drug amitriptyline oxycodone adisinsight https://adisinsight.springer.com/drugs/800087019?error=cookies_not_supported&code=a03d6efd-6fef-4816-8a04-2fd7dc461667 FT 019 - AdisInsight FT 019 is a gene therapy being developed by Frontera Therapeutics for the treatment of an ophthalmological degenerative disorder [eye disorders in development ft adisinsight https://adisinsight.springer.com/drugsafety/801042390?error=cookies_not_supported&code=d9eb54e8-c402-41a9-b9c2-c027c60ce834 Antineoplastics/dexamethasone/pegfilgrastim - AdisInsight Adjuvant antineoplastic therapy for breast cancer with pegfilgrastim support was associated with leucocytosis in one woman and febrile neutropenia in two other antineoplastics dexamethasone pegfilgrastim adisinsight https://adisinsight.springer.com/drugsafety/803192984?error=cookies_not_supported&code=3fdd3f19-da13-4a1a-bb01-9deda70a6a34 Cyclophosphamide/fludarabine/rituximab - AdisInsight In a retrospective study, 2 elderly patients [ages and sexes not stated] were described in which 1 patient developed pancytopenia with autoimmune haemolytic cyclophosphamide fludarabine rituximab adisinsight https://adisinsight.springer.com/drugs/800083919?error=cookies_not_supported&code=2ed8e101-30ee-4ece-ad87-0d512375d359 M2R 003 - AdisInsight M2R 003 is a cell therapy being developed by M2R lab for the treatment of adult respiratory distress syndrome. It is designed using M2R technology. Preclinical adisinsight https://adisinsight.springer.com/drugsafety/803892222?error=cookies_not_supported&code=8b348868-090d-463b-9b4e-8972cc309476 Orelabrutinib - AdisInsight In a single-centre, retrospective study of 10 patients conducted between January 2021 and December 2022, 4 patients [ages and sexes not stated] were described, adisinsight https://adisinsight.springer.com/drugsafety/803551773?error=cookies_not_supported&code=993cde3c-6ac3-48e9-aefb-05f843d7690b Pyrazinamide - AdisInsight A 24-year-old woman had deranged liver function tests during treatment with pyrazinamide for lupus vulgaris.The woman presented in August 2018 with complaints pyrazinamide adisinsight https://adisinsight.springer.com/drugs/800053708?error=cookies_not_supported&code=9c01f435-e490-4333-939b-600dd15e815f Research programme: T cell therapeutics - Adaptive Biotechnologies/Genentech - AdisInsight Neoantigen directed personalised T-cell therapies are being developed by Adaptive Biotechnologies in collaboration with Genentech for the treatment of a broad research programme t cell adaptive biotechnologies therapeutics genentech https://adisinsight.springer.com/drugsafety/803432336?error=cookies_not_supported&code=2c36014b-7a0d-4b28-bb7d-29d4f726cf2e Niacin - AdisInsight In a report , 5 patients (4 females,1 male) [not all ages stated] were described, who developed pseudo allergy manifested as facial flushing alone (n=2), facial niacin adisinsight https://adisinsight.springer.com/drugsafety/800354573?error=cookies_not_supported&code=52f85651-8e4a-456f-8d54-f5294dec4ec3 Nitric oxide - AdisInsight The use of nitric oxide as a pulmonary dilator after lung transplantation may have caused lower motor neuron damage in a 58-year-old woman with alcoholism.After nitric oxide adisinsight https://adisinsight.springer.com/drugs/800048366?error=cookies_not_supported&code=39164105-eb74-49f9-8f64-8a9255830a8a Albumin-bound paclitaxel - NAL Pharma - AdisInsight NAL Pharma is developing NAL 1845, an injection formulation of albumin-bound paclitaxel [see Adis Insight Drug profile 800016962], a tubulin inhibitor, for the albumin bound paclitaxel nal pharma https://adisinsight.springer.com/drugsafety/803910386?error=cookies_not_supported&code=a3c55992-d06e-40d3-bb4a-0b0a9c33628f Lenvatinib/Pembrolizumab - AdisInsight A cohort of 92 elderly patients with advanced recurrent endometrial cancer received combination therapy with lenvatinib and pembrolizumab. Lenvatinib was lenvatinib pembrolizumab adisinsight https://adisinsight.springer.com/drugs/800058258?error=cookies_not_supported&code=2db38365-c53b-40dd-ac23-c5796006d51c OQL 041 - AdisInsight OQL 041 is being developed by OnQuality Pharmaceuticals for the treatment of diarrhoea induced by EGFR inhibitor in cancer patients. Early research is underway oql adisinsight https://adisinsight.springer.com/drugsafety/803180766?error=cookies_not_supported&code=88c829f9-6eee-4866-b17e-51d2317a1e36 Steroids/tacrolimus - AdisInsight A 20-year-old man developed hypercalcaemia, disseminated metastatic tissue calcification, liver failure and heart failure following treatment with tacrolimus steroids tacrolimus adisinsight https://adisinsight.springer.com/drugsafety/801012024?error=cookies_not_supported&code=d40fbd51-c9c3-458e-8348-9ffec4458fcc Pancuronium bromide - AdisInsight A 41-year-old man developed prolonged neuromuscular blockade after receiving an accidental epidural injection of pancuronium bromide prior to surgery for rectal bromide adisinsight https://adisinsight.springer.com/drugsafety/803928162?error=cookies_not_supported&code=8833d4e6-dbf0-4dba-9fac-142157480692 Anabolic steroids - AdisInsight A 50-year-old male powerlifter experienced acute exercise-induced compartment syndrome of the right lower leg after an 815-lb squat, in a context where anabolic anabolic steroids adisinsight https://adisinsight.springer.com/drugsafety/803925242?error=cookies_not_supported&code=7d1718c5-c1b2-45cc-a42d-b57f4ec6417c Rituximab - AdisInsight Patients with diffuse large B-cell lymphoma (DLBCL) or follicular lymphoma (FL) received intravenous rituximab, either as biosimilars or the original rituximab adisinsight https://adisinsight.springer.com/drugsafety/800502280?error=cookies_not_supported&code=90c1c73e-7560-446b-856f-a53ce6a86976 Nicardipine - AdisInsight A 56-year-old man with a 3-year history of stable effort angina and reduction in diameter of all 3 major coronary vessels had 4mm ST segment depression on nicardipine adisinsight https://adisinsight.springer.com/drugsafety/803904929?error=cookies_not_supported&code=c0b4e417-ca3f-4831-8e5c-8afecaea5f19 Enoxaparin-sodium/treprostinil - AdisInsight A 29-year-old woman received treprostinil for pulmonary arterial hypertension (PAH) and enoxaparin-sodium as anticoagulant therapy during pregnancy [dosages not enoxaparin sodium treprostinil adisinsight https://adisinsight.springer.com/drugsafety/803874379?error=cookies_not_supported&code=82477632-aa4e-4fdd-8933-3a926fbeaf88 Warfarin - AdisInsight In a retrospective cohort study of 111 patients, conducted from March 2015 to September 2018, a patient [age and sex not stated] was described, who developed warfarin adisinsight https://adisinsight.springer.com/drugsafety/803275114?error=cookies_not_supported&code=dc90ac95-4f8f-4f08-b44f-1e7e43399454 Amoxicillin/clavulanic-acid - AdisInsight A 54-year-old man developed type I Kounis syndrome during treatment with amoxicillin/clavulanic acid [amoxicillin/clavulanate; Croxilex].The man, who was amoxicillin clavulanic acid adisinsight https://adisinsight.springer.com/drugsafety/803497909?error=cookies_not_supported&code=5cb4bb8a-2323-440b-b1cf-0b4427e2fff7 Pioglitazone - AdisInsight A 52-year-old man received off-label treatment with pioglitazone for autoimmune pulmonary alveolar proteinosis.The man was diagnosed with autoimmune pulmonary pioglitazone adisinsight https://adisinsight.springer.com/drugsafety/803761542?error=cookies_not_supported&code=abf3bf86-585c-4e65-b7b8-7dd30e1dc23b Nitrofurantoin - AdisInsight In a study of 23 patients, 12 women aged 28-86 years were described, who developed liver injury or autoimmune-like hepatitis during treatment with nitrofurantoin adisinsight https://adisinsight.springer.com/drugsafety/803604400?error=cookies_not_supported&code=1c2907d6-ea13-4baa-9c93-9c486f3a74b1 Myocarditis with Pfizer-BioNTech's COVID-19 vaccine in Israel - AdisInsight Two recent studies used differing methods to assess the association between receipt of Pfizer-BioNTech's COVID-19 vaccine in Israel and the development of in israel myocarditis pfizer biontech https://adisinsight.springer.com/drugsafety/803053372?error=cookies_not_supported&code=afe049bf-5d78-4cba-a494-4c8fa127f8c9 Lamotrigine - AdisInsight Two patients experienced a false-positive phencyclidine (PCP) results on a rapid urine toxicology screen during treatment with oral lamotrigine [Lamictal].A lamotrigine adisinsight https://adisinsight.springer.com/drugsafety/803421063?error=cookies_not_supported&code=e8cc6f59-3114-449f-b8a6-99111ab3c4e5 Prednisone - AdisInsight A 69-year-old woman developed hyperkinetic delirium during treatment with prednisone for rheumatoid arthritis (RA).The woman had a 15-year history of RA. She prednisone adisinsight https://adisinsight.springer.com/drugs/800086839?error=cookies_not_supported&code=2e3b31d5-d814-400d-a5c4-ce9e07f3ba1b Tetrapeptide analgesic - PVP Labs - AdisInsight Taphalgin, a first-in-class subcutaneously administered tetrapeptide analgesic (L-tyrosyl-D-arginyl-L-phenylalanylglycinamide) which is a highly selective analgesic pvp labs adisinsight https://adisinsight.springer.com/trials/700040949?error=cookies_not_supported&code=0a1c9c4d-3d09-4db2-a715-17995ac441e6 Oral Contraception and Ovarian Suppression in Women With Different Weights. - AdisInsight This study compared the efficacy and pharmacodynamics of ethinylestradiol/levonorgestrel [Portia and Lessina] for the prevention of pregnancy in patients with oral contraception ovarian suppression https://adisinsight.springer.com/drugsafety/800382960?error=cookies_not_supported&code=20247365-7305-4395-81a9-80f7dc50b150 Sertraline - AdisInsight Although sertraline has been reported to induce hypomania in 2 adults and mania in a child, the following case is the first of sertraline-induced mania in an sertraline adisinsight https://adisinsight.springer.com/drugsafety/800019489?error=cookies_not_supported&code=1ee7ee4b-1ef2-439c-8aa2-cd1165420452 Fluorescein - AdisInsight Fluorescein 10% (5ml) was injected into the right antecubital vein for angiography in a 62-year-old woman with metamorphopsia and a history of compromised fluorescein adisinsight https://adisinsight.springer.com/drugsafety/803634138?error=cookies_not_supported&code=3f4f3f46-51d8-4e29-b377-fecda040326e Magnesium sulfate - AdisInsight In a study of 233 pregnant women enrolled in the Preeclampsia Obstetric Adverse Events (PROVE) biobank during period between April 2018 and March 2020, two magnesium sulfate adisinsight https://adisinsight.springer.com/drugsafety/803882614?error=cookies_not_supported&code=60713ce7-99b5-4eca-b5ba-cd36933fe7ff Amfetamine/Furosemide - AdisInsight A 61-year-old man developed intestinal ischaemia during treatment with amfetamine. Additionaly, he exhibited lack of efficacy during treatment with furosemide amfetamine furosemide adisinsight