adisinsight - Robuta Search

https://adisinsight.springer.com/drugs/800052708?error=cookies_not_supported&code=be36c022-20aa-45f3-bd88-333785457ff0 CB 280 - AdisInsight CB 280 was an orally administered, small molecule arginase inhibitor being developed by Calithera Biosciences for the treatment of cystic fibrosis. Arginase cb adisinsight https://adisinsight.springer.com/drugsafety/803929550?error=cookies_not_supported&code=d76b14e3-9514-40ba-8114-4f74bb1f58bd Pegfilgrastim-related AEs identified in FAERS - AdisInsight Treatment with pegfillgrastim (Neulasta) in patients with solid tumours is associated with adverse events (AEs) such as angioedema, drug hypersensitivity and related aes identified faers adisinsight https://adisinsight.springer.com/drugsafety/800501686?error=cookies_not_supported&code=eeea70d1-ac55-454b-99c4-a97eea2a9b0e Benzoyl peroxide - AdisInsight benzoyl peroxide adisinsight https://adisinsight.springer.com/drugsafety/803167812?error=cookies_not_supported&code=d094a4ae-b323-480e-8a9a-4e8c8251d822 Ibuprofen - AdisInsight An 84-year-old man developed bleeding duodenal ulcer and acute oesophageal necrosis following treatment with ibuprofen [Route, dosage, indication, duration of ibuprofen adisinsight https://adisinsight.springer.com/drugsafety/803782081?error=cookies_not_supported&code=101a5030-30df-4de1-9acd-c1b210c8cabf Mycophenolate-mofetil - AdisInsight A 11-month-old girl developed colitis during immunosuppressive treatment with mycophenolate mofetil [dosage not stated].The girl underwent liver transplantation mycophenolate mofetil adisinsight https://adisinsight.springer.com/drugsafety/803927877?error=cookies_not_supported&code=e1ba1f27-0694-491e-93b0-da23916dc7b0 Ibrutinib - AdisInsight Among 641 patients [age and sex not stated] with chronic lymphocytic leukaemia who received ibrutinib [dose, route and duration not stated], some experienced ibrutinib adisinsight https://adisinsight.springer.com/drugsafety/803229212?error=cookies_not_supported&code=0d829b49-cc89-4901-a7c6-259f8a71fa7b Imatinib - AdisInsight An 88-year-old man developed pleural effusion during therapy with imatinib.The man presented with two weeks history of a dry cough and gradually progressive imatinib adisinsight https://adisinsight.springer.com/drugsafety/803367123?error=cookies_not_supported&code=b5714ca7-d19b-44fe-8f44-cb4376b1d5a7 Sertraline - AdisInsight A 78-year-old woman developed bilateral cystoid macular oedema (CME) during treatment with sertraline for psychotic depression.The woman presented with sertraline adisinsight https://adisinsight.springer.com/drugsafety/803229767?error=cookies_not_supported&code=f47a7dfa-7521-4ff1-a924-5e50c78fcd08 Bupivacaine/epinephrine - AdisInsight A 64-year-old woman developed Harlequin syndrome following treatment with bupivacaine and epinephrine.The woman presented for left mastectomy for multifocal bupivacaine epinephrine adisinsight https://adisinsight.springer.com/drugsafety/803929204?error=cookies_not_supported&code=500d4f35-f1cc-414a-95f7-a2a17ed82c5b Buprenorphine - AdisInsight Four patients [ages and sexes not stated] with cancer-related pain or chronic pain and a history of malignancy, who were opioid tolerant, initiated buprenorphine adisinsight https://adisinsight.springer.com/drugsafety/803846887?error=cookies_not_supported&code=b88d046a-3ab1-4e1e-91e8-225451f1557d Lisinopril - AdisInsight A 43-year-old woman developed urticarial vasculitis during the treatment of lisinopril [indication not stated].The woman had significant history of type 2 lisinopril adisinsight https://adisinsight.springer.com/patents/800013176 Estradiol acetate - AbbVie - AdisInsight estradiol acetate abbvie adisinsight https://adisinsight.springer.com/trials/700309134?error=cookies_not_supported&code=ccc0aa43-01ca-4d19-96bf-5a0dfcb17b48 Liver Safety Assessment During Ulipristal Acetate Treatment for Uterine Fibroids - AdisInsight The aim of the present study is to evaluate whether changes in transaminase levels or other drug induced liver injury markers occur in patients receiving liver safety treatment for uterine fibroids assessment https://adisinsight.springer.com/drugsafety/803928277?error=cookies_not_supported&code=480eea00-7d99-495a-b865-0435ea217b7f Multiple drugs - AdisInsight Fourteen patients, predominantly men with a median age of 63 years, had advanced cutaneous squamous cell carcinoma that was refractory due to lack-of-efficacy multiple drugs adisinsight https://adisinsight.springer.com/drugsafety/803928328?error=cookies_not_supported&code=e86a007b-b5dd-4f4b-a4a8-aa1ae7dc26e0 Patiromer - AdisInsight Fifty-nine patients [age and sex not stated] with chronic kidney disease and hyperkalaemia, a condition common in those treated with adisinsight https://adisinsight.springer.com/drugsafety/803883840?error=cookies_not_supported&code=9d77c799-f924-445c-b041-23164a73d220 Fezolinetant-related liver damage - AdisInsight The Netherlands Medicines Evaluation Board is warning of the risk of fezolinetant [Veoza]-related liver damage, advises the Netherlands pharmacovigilance centre liver damage related adisinsight https://adisinsight.springer.com/drugsafety/803679036?error=cookies_not_supported&code=c3c83eb4-ec20-4337-b5f9-b734531ddebe Clindamycin - AdisInsight In a retrospective study between 2010 and 2019 involving 33 patients treated for Cutibacterium acnes infections, one patient [age and sex not stated] was clindamycin adisinsight https://adisinsight.springer.com/drugsafety/803923763?error=cookies_not_supported&code=43f339f3-0893-4506-8b99-ce35b0c0b8e9 Bevacizumab/Tipiracil/trifluridine - AdisInsight One hundred and forty-three patients with chemotherapy-refractory metastatic colorectal cancer received TAS-102 (tipiracil/trifluridine) and bevacizumab and bevacizumab adisinsight https://adisinsight.springer.com/drugsafety/803592381?error=cookies_not_supported&code=9f0ad2ea-29ba-4d14-864f-35b9f0029239 Amphotericin-B-liposomal - AdisInsight A 64-year-old woman developed asystolic cardiac arrest following treatment with amphotericin-B-liposomal for presumed cryptococcal meningitis.The woman amphotericin b liposomal adisinsight https://adis.springer.com/cookie-policy?error=cookies_not_supported&code=706bf7dd-8771-4f1a-8414-c55b92572549 Cookie Policy - AdisInsight cookie policy adisinsight https://adisinsight.springer.com/trials/700391840?error=cookies_not_supported&code=e248fb3f-5ca3-4c51-9803-83620fc59e74 A phase 2 study of GPV-381 in advanced periodontitis. - AdisInsight This Phase 2 study is designed to assess whether targeting gingipain-driven biology can meaningfully alter disease progression and deliver improved clinical phase study https://www.springernature.com/de/librarians/products/databases-solutions/corporate-health/pharma-biotechnology/therapeutic-research-areas/oncology/adisinsight-oncology AdisInsight Oncology | For Librarians | Springer Nature for librarians adisinsight oncology springer nature https://adisinsight.springer.com/drugsafety/807212156?error=cookies_not_supported&code=8de3acd9-c65b-4c99-a03d-47ab3c51a280 Methotrexate - AdisInsight Methotrexate-associated toxic hepatitis occurred in a 60-year-old woman undergoing treatment for breast cancer.Following tumourectomy, the woman received methotrexate adisinsight https://adisinsight.springer.com/drugsafety/803429304?error=cookies_not_supported&code=ac808356-7d2e-4053-a987-1057bd24251e Docetaxel/paclitaxel - AdisInsight A 51-year-old woman developed drug allergy during treatment with paclitaxel and docetaxel [routes not stated] for multiple bone and dural metastases.The woman, docetaxel paclitaxel adisinsight https://adisinsight.springer.com/drugsafety/803928879?error=cookies_not_supported&code=3e1c5b5a-af02-4b3b-afc4-c6f95c69d7a1 Buprenorphine/Naloxone - AdisInsight Seven adults (five women and two men; average age 57 years) with chronic noncancer pain received buprenorphine/naloxone [dose, route and duration not stated]. buprenorphine naloxone adisinsight https://adisinsight.springer.com/drugsafety/803908712?error=cookies_not_supported&code=90efdba8-cdcd-417c-bf00-4a38ab4f2265 Trastuzumab-emtansine - AdisInsight A cohort of 47 adult patients (median age 55 years, 46 female and 1 male) with HER2-positive metastatic breast cancer developed thrombocytopenia during trastuzumab adisinsight https://adisinsight.springer.com/drugsafety/800889199?error=cookies_not_supported&code=58bf957e-5bb9-49d3-9cf2-eae9efe9e8aa Sodium stibogluconate - AdisInsight Treatment with sodium stibogluconate for visceral leishmaniasis was associated with dyserythropoiesis in a 37-year-old man with HIV infection who had been sodium adisinsight https://adisinsight.springer.com/drugsafety/803839309?error=cookies_not_supported&code=1fd74373-cfcc-4e3b-9208-78ea12ed5c0d Glucose/paracetamol/sodium-bicarbonate - AdisInsight A 26-year-old woman received paracetamol, along with sodium-bicarbonate and glucose for starvation ketoacidosis during pregnancy [not all routes and indications sodium bicarbonate glucose paracetamol adisinsight https://adisinsight.springer.com/drugsafety/803615850?error=cookies_not_supported&code=0a3edf64-7245-4453-a9a3-44c259ae867f Marijuana/tacrolimus - AdisInsight A 45-year-old woman developed posterior reversible encephalopathy following concomitant administration of tacrolimus for immunosuppressive therapy and marijuana marijuana tacrolimus adisinsight https://adisinsight.springer.com/drugsafety/803850806?error=cookies_not_supported&code=1b7b46a8-eda2-4d17-abce-ca41fca07caf Ketamine - AdisInsight In a retrospective chart review of 61 patients with chronic pain treated with ketamine between January 2020 and June 2022, a patient [age and sex not stated] ketamine adisinsight https://adisinsight.springer.com/patents/800050611 Dexmedetomidine - BioXcel Therapeutics - AdisInsight dexmedetomidine therapeutics adisinsight https://adisinsight.springer.com/drugsafety/803610279?error=cookies_not_supported&code=52b96c1c-9ebd-4dff-b313-f4e857b40dec Ibuprofen - AdisInsight A 45-year-old man developed tongue swelling during treatment with ibuprofen [indication not stated].The man presented to the emergency department (ED) with ibuprofen adisinsight https://adisinsight.springer.com/drugsafety/803924103?error=cookies_not_supported&code=74821d56-75b6-488b-a905-01b47a877ab1 Aflibercept - AdisInsight An 83-year-old man with neovascular age-related macular degeneration and diabetes mellitus developed endophthalmitis in the left eye following intravitreal aflibercept adisinsight https://adisinsight.springer.com/trials/700043564?error=cookies_not_supported&code=c1aadc20-c183-470d-bca3-0d0a6a4ac629 Phase I multiple-dose trial in male volunteers. - AdisInsight This phase I, placebo-controlled, multiple ascending dose trial will assess the tolerability and pharmacokinetics of multiple doses of oral SUVN 502 [Suven Life phase i multiple dose trial male https://adisinsight.springer.com/trials/700315164?error=cookies_not_supported&code=19173001-c1d2-4e5e-b568-4059deb975b9 To assess Safety and immunogenicity in human infants - AdisInsight To evalutate safety and immunogenicity of PCV15 in human infants assess safety immunogenicity human infants https://adisinsight.springer.com/drugsafety/803610280?error=cookies_not_supported&code=d25f29bb-b251-4274-a4b6-29ca6ab3b988 mRNA-1273 - AdisInsight A 61-year-old man developed Guillain-Barre syndrome following administration of mRNA-1273 for vaccination [route not stated].The man received second dose of mrna adisinsight https://adisinsight.springer.com/patents/800004407 Tenecteplase - Genentech - AdisInsight tenecteplase genentech adisinsight https://adisinsight.springer.com/drugsafety/803590889?error=cookies_not_supported&code=7a4ed9ce-34e1-4e6e-8631-03911cd4ddb5 Abatacept/adalimumab - AdisInsight In a single center retrospective cohort study of 1136 patients with juvenile idiopathic arthritis (JIA), who were treated between 2004 and 2020, two patients abatacept adalimumab adisinsight https://adisinsight.springer.com/drugsafety/803900241?error=cookies_not_supported&code=16409b00-8a3e-43e8-8d3d-6e218857427f Multiple drugs - AdisInsight A 58-year-old woman developed disseminated nocardiosis during treatment with methylprednisolone and cyclophosphamide for systemic lupus erythematosus (SLE). multiple drugs adisinsight https://adisinsight.springer.com/drugsafety/803108854?error=cookies_not_supported&code=c90d5ab9-c673-4fb3-b879-2af3d6c90587 Combating antibiotic resistance: national security priority in US - AdisInsight The US Federal Government has made combating antibacterial-resistant bacteria a national security priority, and has established the Task Force for Combating antibiotic resistance national security in us priority adisinsight https://adisinsight.springer.com/drugsafety/803631476?error=cookies_not_supported&code=cdf66be7-3ee8-43cc-a023-a0cb305fc0bf Carbamazepine/lacosamide/oxcarbazepine - AdisInsight A study of 201 patients with newly diagnosed focal epilepsy (FE) was conducted to analyse the effect of sodium-channel blocker monotherapy on pharmacodynamic carbamazepine oxcarbazepine adisinsight https://adisinsight.springer.com/drugsafety/800430949?error=cookies_not_supported&code=b307080a-3dc8-4e19-995d-c5840d3e9bca Miconazole - AdisInsight miconazole adisinsight https://adisinsight.springer.com/drugsafety/803898372?error=cookies_not_supported&code=98e9be9a-f8f3-482e-a360-f9a46ac051de Amphotericin-B-liposomal/Posaconazole/Voriconazole - AdisInsight "Recorded adverse drug events associated with voriconazole and posaconazole included transaminitis (4 patients), QTc prolongation (1 patient), and amphotericin b liposomal posaconazole voriconazole adisinsight https://adisinsight.springer.com/drugsafety/803533220?error=cookies_not_supported&code=60685f58-1c9e-489f-8a17-d690bcb1f5ab Doxycycline - AdisInsight In a retrospective study of 7 patients treated for uveitis caused by Rickettsia conorii infection between May 1999 and March 2006, a 54-year-old woman and a doxycycline adisinsight https://adisinsight.springer.com/drugsafety/801103191?error=cookies_not_supported&code=0be6f9c5-216e-48b5-bd6e-ba6217dff0dd Rabies vaccine - AdisInsight An 11-year-old girl developed acute demyelinating encephalomyelitis after receiving sheep brain neural rabies vaccine.The girl had received seven doses of SC rabies vaccine adisinsight https://adisinsight.springer.com/drugsafety/800979681?error=cookies_not_supported&code=545bd044-df3c-490d-a428-5763fdb8d9e8 Gefitinib - AdisInsight Two women developed paronychia and skin hyperpigmentation during treatment with gefitinib [Iressa] for non-small cell lung cancer.A 43-year-old woman developed gefitinib adisinsight https://adisinsight.springer.com/drugsafety/803910090?error=cookies_not_supported&code=7de82bb5-5480-4054-b0eb-28be6454ad0b Echinocandins - AdisInsight A retrospective study of 198 patients with fungemia analyzed the prevalence and risk factors for ocular lesions and the efficacy of routine screening. Among 115 adisinsight https://adisinsight.springer.com/drugsafety/803082240?error=cookies_not_supported&code=57974526-8efe-423f-85ad-44d932943e89 Propolis - AdisInsight An 18-year-old girl developed allergic contact cheilitis and perioral dermatitis after using topical propolis to treat gingivitis.The girl presented with propolis adisinsight https://adisinsight.springer.com/drugsafety/803666954?error=cookies_not_supported&code=be5657ed-63a5-45d4-b9fc-d86344f946eb Risperidone - AdisInsight A 45-year-old woman developed hyperprolactinaemia during treatment with risperidone for schizoaffective disorder bipolar type.The woman, who had schizoaffective risperidone adisinsight https://adisinsight.springer.com/drugs/800086291?error=cookies_not_supported&code=b24f6017-7e64-46ea-bb09-ca664db5a440 Meloxicam injection - Nanjing Delova Biotech - AdisInsight QP 001 is an intravenous, 24 hours long acting, single dose formulation of meloxicam being developed by Nanjing Delova Biotech for the treatment of meloxicam injection nanjing biotech adisinsight https://adisinsight.springer.com/drugsafety/803906780?error=cookies_not_supported&code=49556925-4b9c-439a-bb39-7e63fb806fee Multiple drugs - AdisInsight An adult woman [exact age not stated] exhibited treatment failure during treatment with colchicine, sodium-cromoglicate, hydroxyzine, pentoxifylline, gabapentin multiple drugs adisinsight https://adisinsight.springer.com/patents/800008587 Telithromycin - AdisInsight adisinsight https://adisinsight.springer.com/drugs/800058947?error=cookies_not_supported&code=bb95e663-5794-40a6-a0be-73cbf5f10c27 SHR 1802 - AdisInsight SHR 1802 is humanised monoclonal antibody targeting leukocyte activating gene-3 (LAG-3) protein (CD223-antigen), being developed by Jiangsu HengRui Medicine for shr adisinsight https://adisinsight.springer.com/drugsafety/801064377?error=cookies_not_supported&code=c2c1e380-2997-459e-a4c1-80ce358adaed Ciclosporin - AdisInsight Three male transplant recipients developed leukoencephalopathy during immunosuppressive treatment with ciclosporin [dosages not stated].A 43-year-old man ciclosporin adisinsight https://adisinsight.springer.com/drugsafety/803133156?error=cookies_not_supported&code=9dfea59f-9c63-4f5d-bfdf-cd18a8d01b92 Rabies immune globulin/rabies vaccine - AdisInsight A 55-year-old man developed paralytic rabies due to post-exposure prophylaxis failure following vaccination with rabies vaccine and rabies immune-globulin [not immune globulin rabies vaccine adisinsight https://adisinsight.springer.com/drugsafety/803883807?error=cookies_not_supported&code=e935866b-d10c-4148-8ec7-4e37dc1a6930 Ipilimumab/nivolumab - AdisInsight A 70-year-old woman developed immune checkpoint inhibitor (ICI)-induced myocarditis with myositis and myasthenia gravis overlap syndrome (IM3OS) following ipilimumab nivolumab adisinsight https://adisinsight.springer.com/drugsafety/800877610?error=cookies_not_supported&code=33dd91e2-3f35-4125-8d5d-15ce2e8313ac Terbinafine - AdisInsight Eight patients developed arthralgias after beginning treatment with terbinafine; fever and urticaria also developed in some of the patients.The patients were 5 terbinafine adisinsight https://adisinsight.springer.com/drugsafety/800644198?error=cookies_not_supported&code=d18cfeb8-bcec-4eac-b831-cf81d5989bc5 Tacrolimus interaction - AdisInsight A 46-year-old heart-lung transplant recipient experienced an interaction between tacrolimus and itraconazole and subsequently died of multiorgan failure.The tacrolimus interaction adisinsight https://adisinsight.springer.com/drugsafety/803928693?error=cookies_not_supported&code=7bc88a59-5a64-45d2-a677-2896ba9eb830 Sacituzumab govitecan - AdisInsight Eighty-seven patients [age and sex not stated] with advanced HER2-negative metastatic breast cancer at a single US institution received sacituzumab adisinsight https://adisinsight.springer.com/drugsafety/803092349?error=cookies_not_supported&code=574f6394-7117-4695-ac95-96f38676dfd6 Orlistat not found to alter risk of colorectal cancer - AdisInsight Findings from a US-based retrospective study support the US FDA's determination of "no increased risk of colorectal cancer associated with the use of not found colorectal cancer orlistat alter risk https://adisinsight.springer.com/drugsafety/803646929?error=cookies_not_supported&code=b25e1f4f-e3ca-42aa-a7e7-4af27e6dbccb Gefitinib - AdisInsight A man in his 60s [exact age not stated] developed acquired resistance to gefitinib with transformation of lung adenocarcinoma (ADC) to metastatic small cell gefitinib adisinsight https://adisinsight.springer.com/drugsafety/803844995?error=cookies_not_supported&code=d24629e4-ab71-4a16-bae8-8531d933f628 Rivastigmine-related QT prolongation and torsades de pointes - AdisInsight The National Pharmaceutical Regulatory Agency (NPRA) of Malaysia is advising that use of rivastigmine for the treatment of dementia associated with Alzheimer's rivastigmine related qt prolongation torsades https://adisinsight.springer.com/drugsafety/803759798?error=cookies_not_supported&code=0de90dea-93b4-4c14-b201-890906ed91f5 Immune-globulin/methylprednisolone/piperacillin/tazobactam - AdisInsight A 38-year-old man exhibited a lack of efficacy following treatment with methylprednisolone and immune-globulin for inflammatory polymyositis and immune globulin methylprednisolone adisinsight https://adisinsight.springer.com/drugsafety/800754607?error=cookies_not_supported&code=a7f99810-4a02-49fd-a3d5-df47259da77b Amiodarone - AdisInsight Amiodarone may have played a role in the development of depression in a 65-year-old woman with a longstanding obsessive-compulsive disorder.The woman started amiodarone adisinsight https://adisinsight.springer.com/drugsafety/803464034?error=cookies_not_supported&code=8e1a0142-e060-4c2f-8fdf-f1a999296892 Dual vs triple antiplatelet/anticoagulant therapy after PCI - AdisInsight Dual therapy (with a direct oral anticoagulant [DOAC] and a P2Y12 inhibitor) appears to be associated with a reduced risk of bleeding in patients with atrial dual vs triple anticoagulant therapy https://adisinsight.springer.com/drugsafety/803740403?error=cookies_not_supported&code=5dcfba0a-5cc4-4fc8-8d09-56200ebfff94 Denosumab/pamidronic acid - AdisInsight In a case series, 2 patients (a 27-year-old woman and a 52-year-old man) were described, who exhibited lack of efficacy while being treated with pamidronic acid denosumab acid adisinsight https://adisinsight.springer.com/drugsafety/803866053?error=cookies_not_supported&code=30a1176b-dfc3-4d5a-84e9-61e2f0e68ce0 Glecaprevir/pibrentasvir - AdisInsight In a retrospective review, involving 13 patients at center 1 who underwent heart transplantation from hepatitis C positive donors from 2019 and 2021; one adisinsight https://adisinsight.springer.com/drugsafety/803172478?error=cookies_not_supported&code=9cf5dc4e-0c0b-417c-8427-bbf25ff26a7d Norepinephrine/vasopressin - AdisInsight A 53-year-old man developed cardiac failure, severe mitral valve regurgitation (MR), left ventricular outflow tract obstruction (LOVT) and reperfusion injury norepinephrine vasopressin adisinsight https://adisinsight.springer.com/drugsafety/800270200?error=cookies_not_supported&code=096d5134-3447-4720-a26d-3df94cb55a94 Valproic acid - AdisInsight Valproic acid-associated pancreatitis developed in an 11-year-old girl with juvenile neuronal ceroid lipofuscinosis.The girl presented with severe abdominal valproic acid adisinsight https://adisinsight.springer.com/drugsafety/800801613?error=cookies_not_supported&code=ba528d86-9323-4693-98dc-dec7255e52af Reboxetine - AdisInsight A 72-year-old man developed hyponatraemia due to inappropriate antidiuretic hormone secretion after starting treatment with reboxetine for depression.During adisinsight https://adisinsight.springer.com/drugs/800050959?error=cookies_not_supported&code=95026784-9edc-4030-9dfe-ec8fd5de1b5f Research programme: small molecule therapeutics - X-Chem - AdisInsight X-Chem, in collaboration with a consortium of Harvard T.H. Chan School of Public Health, University of Massachusetts, Weill Medical College of Cornell research programme small molecule therapeutics x chem https://adisinsight.springer.com/drugsafety/803608230?error=cookies_not_supported&code=3d0b7d14-020b-4489-8cb7-07068f2477b0 Osimertinib - AdisInsight In a single institution, retrospective study of 234 patients with epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC), who were osimertinib adisinsight https://adisinsight.springer.com/drugs/800037457?error=cookies_not_supported&code=a80dc20b-1520-4ac5-85cf-b437d0aa6c37 Levonorgestrel - AbbVie - AdisInsight Allergan (now AbbVie) acquired intrauterine levonorgestrel that is intended for use as a contraceptive agent and for the treatment of heavy uterine bleeding levonorgestrel abbvie adisinsight https://adisinsight.springer.com/drugsafety/803929412?error=cookies_not_supported&code=90a488ee-7448-49dd-9daa-c6a8995251a4 Buprenorphine/Pethidine - AdisInsight Patients [age not stated, sex not stated] undergoing surgery for thoracic or lumbar vertebral fractures received sublingual buprenorphine 0.4 mg in three buprenorphine adisinsight https://adisinsight.springer.com/drugsafety/803382232?error=cookies_not_supported&code=7af49e96-3da4-4694-a27a-e289a533b2af Multiple drugs - AdisInsight A 91-year-old woman developed acute kidney injury (AKI) during treatment with telmisartan and rosuvastatin for hypertension and middle cerebral artery multiple drugs adisinsight https://adisinsight.springer.com/drugsafety/803086383?error=cookies_not_supported&code=a3f1595c-6cfd-42ab-b711-928173be5268 Lisdexamfetamine - AdisInsight A 49-year-old man developed high altitude pulmonary oedema (HAPE) during treatment with lisdexamfetamine [Vyvanse].The man, who was an experienced mountaineer lisdexamfetamine adisinsight https://adisinsight.springer.com/drugsafety/803908262?error=cookies_not_supported&code=f42d6b81-e28c-43dd-a3cd-7eb15a8816b1 Tofacitinib - AdisInsight In a retrospective study involving 36 patients with alopecia areata (AA) conducted between January 2021 and December 2023, one patient [age and sex not stated] tofacitinib adisinsight https://adisinsight.springer.com/trials/700383900?error=cookies_not_supported&code=ab1c09d5-f138-4869-b1e0-3fc48dec81f1 5-AminoLevulinic Acid Aided Resection Margins in Sarcoma (5-ALARMS) - AdisInsight The goal of this study is to learn if the intervention using a fluorescent agent 5-Aminolevulinic acid (5-ALA) to aid in the surgical approach to visualize the aminolevulinic acid aided margins sarcoma alarms https://adisinsight.springer.com/drugsafety/803556283?error=cookies_not_supported&code=fd5ea978-e187-4218-9b5d-5d0eaba77a1e Ipilimumab/nivolumab/relatlimab - AdisInsight A 79-year-old woman developed hyperprogression of metastatic vaginal melanoma and myocarditis during treatment with nivolumab and ipilimumab for metastatic ipilimumab nivolumab adisinsight https://adisinsight.springer.com/drugsafety/803927124?error=cookies_not_supported&code=a75b0737-6af8-4ab5-8f68-bf3835c19a29 Ergotamine - AdisInsight A 62-year-old woman with migraine and long-term excessive ergotamine [dose and route not stated] use experienced chronic heart failure secondary to severe adisinsight https://adisinsight.springer.com/drugsafety/803043858?error=cookies_not_supported&code=d3bc2f2e-7699-4ff7-9478-0640a8ac3dc5 Ibandronic acid - AdisInsight A 65-year-old woman developed bilateral simultaneous femoral diaphyseal fractures during treatment with ibandronic acid for osteoporosis.The woman had been ibandronic acid adisinsight https://adisinsight.springer.com/drugsafety/803928993?error=cookies_not_supported&code=511d71b3-c7eb-49d3-95a7-3649c73dff24 Olanzapine/Risperidone - AdisInsight Patients [age and sex not stated] with chronic schizophrenia receiving prolonged antipsychotic therapy experienced metabolic syndrome while treated with olanzapine risperidone adisinsight https://adisinsight.springer.com/drugs/800086934?error=cookies_not_supported&code=135bad81-0bd5-4ddf-b48b-31cb9cee5c7a TNV 108 - AdisInsight TNV 108 is a small molecule, being developed by Tenvie Therapeutics, for the treatment of diabetic peripheral neuropathy [Diabetic neuropathies in development adisinsight https://adisinsight.springer.com/drugsafety/803770673?error=cookies_not_supported&code=1895658f-9820-44d7-a25f-4d2ce20d9ba2 Durvalumab/ipilimumab/nivolumab - AdisInsight In a case series consisting of 6 patients, two patients [ages and sexes not stated] were described, who developed chronic plaque psoriasis following treatment durvalumab ipilimumab nivolumab adisinsight https://adisinsight.springer.com/drugsafety/800967457?error=cookies_not_supported&code=8dd2ed44-ea6d-410d-a2b9-5c842114d4be US Aredia and Zometa labelling change: osteonecrosis risk - AdisInsight In response to spontaneous reports of osteonecrosis of the jaw in patients receiving bisphosphonates, Novartis has issued a `Dear Doctor' letter advising of us labelling change osteonecrosis risk https://adisinsight.springer.com/drugsafety/807200611?error=cookies_not_supported&code=0024d4f7-a4dd-40b1-aa37-9b179259cc58 Nefazodone - AdisInsight Two patients developed selective impairment of motion perception (akinetopsia) during treatment with nefazodone.The first patient, a 47-year-old man, had been adisinsight https://adisinsight.springer.com/trials/700262245?error=cookies_not_supported&code=f766afc5-9247-460c-b5e4-b453b450b084 Phase 3 trial of TB4 in patients with dry eye - AdisInsight This phase 3 study will investigate the effect of Thymosin beta-4 in patients with dry eye in China. in patients dry eye phase trial https://adisinsight.springer.com/drugsafety/803078775?error=cookies_not_supported&code=95167d65-7a0b-41e4-9609-8cff220129b1 Albendazole - AdisInsight A 62-year old man developed severe pancytopenia following treatment with albendazole for recurrence of liver cyst hydatid.The man received albendazole [dosage albendazole adisinsight https://adisinsight.springer.com/drugsafety/803085206?error=cookies_not_supported&code=f4a924fe-e00b-4b1e-9436-f617b2d74f42 Rituximab - AdisInsight A 5-year-old boy developed late-onset neutropenia after receiving rituximab for nephrotic syndrome.The boy had received therapies including tacrolimus and rituximab adisinsight https://adisinsight.springer.com/drugsafety/803841875?error=cookies_not_supported&code=32c0dfa5-9079-42ef-adbe-3a20c57a195b BBIBP-CorV - AdisInsight A 50-year-old man developed synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome following COVID-19 vaccination with BBIBP-CorV.The man adisinsight https://adisinsight.springer.com/drugsafety/803436670?error=cookies_not_supported&code=706bdcb6-4b2b-45ce-b7fa-34d192ef6033 Multiple drugs - AdisInsight In a retrospective review of 30 cases consulted at the Dermatology Department of the University of Puerto Rico from January 2006 to December 2017, 18 patients multiple drugs adisinsight https://adisinsight.springer.com/drugsafety/803926015?error=cookies_not_supported&code=84ef18c7-3785-4cda-9773-32170b1ae60b Abemaciclib - AdisInsight A total of 3423 patients (3407 women and 16 men) with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or early breast abemaciclib adisinsight https://adisinsight.springer.com/drugs/800053767?error=cookies_not_supported&code=5476ead1-5713-4136-8ef7-56af83e910dc Research programme: respiratory virus infections therapeutics - Interna Therapeutics - AdisInsight Interna Therapeutics (previously SirVir) is developing therapeutics based on the Apo-Si technology developed by Aposense for the treatment of respiratory virus research programme respiratory virus infections therapeutics interna https://adisinsight.springer.com/drugsafety/803417156?error=cookies_not_supported&code=6c7b0a41-b56b-49f1-9d96-07eb4013398a Varicella zoster virus vaccine live - AdisInsight A woman in her 80s developed varicella zoster virus infection despite vaccination with varicella zoster virus vaccine live.The woman presented with a moderately varicella zoster virus vaccine live https://adisinsight.springer.com/drugsafety/803928330?error=cookies_not_supported&code=45939f44-a20b-43f2-845c-205035129318 Fentanyl - AdisInsight Ninety-nine patients from England, Wales and Northern Ireland between 1997 and 2024 experienced deaths [onset not stated] associated with fentanyl patches fentanyl adisinsight https://adisinsight.springer.com/drugsafety/801118356?error=cookies_not_supported&code=b4763735-bd6c-4bc7-a9ca-2ed97ad703c8 Asparaginase - AdisInsight Three patients with acute lymphoblastic leukaemia (ALL) developed posterior reversible encephalopathy syndrome (PRES) during treatment with asparaginase.An adisinsight https://adisinsight.springer.com/drugsafety/803898782?error=cookies_not_supported&code=ed0750a3-544b-484d-8e1d-f19155797a3b Amoxicillin/Liraglutide - AdisInsight A 37-year-old woman exhibited lack of efficacy following treatment with amoxicillin for abdominal wall abscess secondary to Granulicatella adiacens infection. amoxicillin liraglutide adisinsight https://adisinsight.springer.com/drugsafety/803923977?error=cookies_not_supported&code=8496577f-1da3-446b-9334-f0b3de33b9f0 Spironolactone - AdisInsight A 47-year-old woman with Gitelman syndrome experienced symptomatic hypotension due to spironolactone, which had been prescribed as part of her management for spironolactone adisinsight https://adisinsight.springer.com/drugsafety/803461605?error=cookies_not_supported&code=abd9b530-8a83-40e7-b8da-4fb0cfb29f8e Secukinumab/methotrexate - AdisInsight In a case series, a 52-year-old and a 69-year-old women were described who developed dyshidrotic eczema during treatment with secukinumab for psoriasis. One secukinumab methotrexate adisinsight https://adisinsight.springer.com/drugsafety/803540320?error=cookies_not_supported&code=b2d72388-7954-48fc-a712-0aa77e085b6a Multiple drugs - AdisInsight A 59-year-old woman developed carcinoid crisis during treatment with dobutamine and vasopressin for cardiogenic shock and worsening of cardiogenic shock during multiple drugs adisinsight