Robuta

Nuclear receptor ROR-gamma, SRC2...

Fab heavy chainFab light chain2-(N-MORPHOLINO)-ETHANESULFONIC ACID

Ligand binding to FARNESOID-X-RECEPTOR

S2H14 antigen-binding (Fab) fragmentNONAETHYLENE GLYCOL

Coronavirus disease (COVID)-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become a global pandemic disease that has...

Crystal Structure of Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with an Ethyl Indazole Compound

Peroxisome proliferator-activated receptor gamma coactivator 1-alphaSteroid hormone receptor ERR11-[4-(3-tert-butyl-4-oxidanyl-phenoxy)phenyl]ethanoneIODIDE ION

interacting selectively and non-covalently with a cytokine receptor.

Antibodies for proteins involved in taste receptor binding pathways, according to their Panther/Gene Ontology Classification

Antibodies for proteins involved in type 3 metabotropic glutamate receptor binding pathways, according to their Panther/Gene Ontology Classification

RECEPTOR BINDING PROTEIN

Crystal structure of mutant Androgen Receptor ligand binding domain H875Y/F877L/T878A with DHT

Vitamin D3 receptor(1S,3R,5Z,7E,20S,23S)-1,3-dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10,25(27)-tetraen-26-one

Aromatic acid chemoreceptorCHLORIDE IONGLYCEROL

Alpha-2 adrenergic receptors have been divided into four pharmacological subtypes based on their differences in affinity for several drugs. Previous studies...

Spike protein S1WRAIR-2134 Fab Heavy ChainWRAIR-2134 Fab Light Chain2-acetamido-2-deoxy-beta-D-glucopyranose

Fab Heavy chainFab Light chainSpike protein S12-acetamido-2-deoxy-beta-D-glucopyranose

Adenosine A2A receptors seem to exist in typical (more in striatum) and atypical (more in hippocampus and cortex) subtypes. In the present study, we investig...

RETINOID X RECEPTOR, BETA6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACIDCHLORIDE IONNICKEL (II) ION

crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen

Androgen receptorFxxLF motif peptide5-ALPHA-DIHYDROTESTOSTERONE

Orexins A (OXA) and B (OXB) and the receptors 1 (OX1R) and 2 (OX2R) for orexins are hypothalamic peptides found in several mammalian organs and participated ...

CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (R)4-METHYL 9cUAB30 AND COACTIVATOR PEPTIDE GRIP-1

Botulinum neurotoxin type A

Interacting selectively and non-covalently with a growth factor receptor.

Estrogen-related receptor gamma(Z)-4-(1-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-HYDROXY-2-PHENYLPENT-1-ENYL)PHENOL

Literature studies, 3D structure data, and a series of sequence analysis techniques were combined to reveal important residues in the structure and function of...

Odorant receptor (OR) genes constitute with 1200 members the largest gene family in the mouse genome. A mature olfactory sensory neuron (OSN) is thought to...

Androgen receptor (AR) plays a critical role in development and maintenance of male reproductive functions and the etiology of prostate cancer. As a...

Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selectively PPAR gamma-modulating ligand VSP-51

Crystal structure of pregnane X receptor ligand binding domain complexed with rifamycin S

Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor

Bot.0671.2Botulinum neurotoxin type B

Lymphatic vessel endothelial hyaluronic acid receptor 12-acetamido-2-deoxy-beta-D-glucopyranosebeta-D-glucopyranuronic acid

Bile acid receptorNuclear receptor coactivator 26-ETHYL-CHENODEOXYCHOLIC ACID

2'-Fluoro-3-(substituted pyridine)epibatidine analogues 7a-e and 8a-e were synthesized, and their in vitro and in vivo nAChR properties were determined....

A direct interaction between the nuclear receptor TR2 and histone deacetylases (HDACs) 3 and 4 is mediated by the DNA binding domain (DBD) of TR2. To test if...

Bile acid receptorCOACTIVATOR PEPTIDE SRC-1 HD35-{[(3beta,5beta,14beta,17alpha)-3-hydroxy-24-oxocholan-24-yl]amino}benzene-1,3-dicarboxylic acid

We have reported previously the cloning and partial characterization of a chick A1 adenosine receptor expressed in the heart. We report herein the cloning of a...

NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor

We conducted preclinical studies in mice using a yeast-produced SARS-CoV-2 RBD subunit vaccine candidate formulated with aluminum hydroxide (alum) and CpG...

Most successful vaccines elicit neutralizing antibodies and this property is a high priority when developing an HIV vaccine. Indeed, passively administered...

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies eCR3022.20 and CC12.3

Antibodies for proteins involved in platelet-derived growth factor receptor binding pathways, according to their Panther/Gene Ontology Classification

AbstractThe collagen-integrin interactions are mediated by the doubly charged Mg2+ cation. In nature this cation seems to have the optimal binding strength t...

Our results suggest that ERX-11 inhibited the proliferation of BCa cells resistant to both endocrine therapy and CDK4/6 inhibitors in a dose-dependent manner...

To map the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and evaluate immune response variations against this virus, it is essential...

Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter

Xanomeline is a novel agonist functionally selective for muscarinic receptors of the M1 subtype. It binds to this receptor in two modes, reversible and...

scientific journal article

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity