https://www.trialx.com/clinical-trials/listings/327772/a-phase-iiia-open-label/
A Phase I/IIa, Open-label, Single-center, Dose-escalation and Dose-expansion Study to Evaluate the...
Clinical trial for Relapsed/Refractory B-cell Non-Hodgkin Lymphoma , A Phase I/IIa, Open-label, Single-center, Dose-escalation and Dose-expansion Study to...
phase isingle centerdose escalationiiaopen
https://profiles.wustl.edu/en/publications/phase-i-open-label-dose-escalation-study-of-the-safety-pharmacoki/
Phase I, Open-Label, Dose-Escalation Study of the Safety, Pharmacokinetics, Pharmacodynamics, and...
phase idose escalationthe safetyopenlabel
https://ctv.veeva.com/study/trivalent-rha-dose-escalation-study-in-elderly-subjects
Trivalent rHA Dose Escalation Study in Elderly Subjects
This study will compare the safety and immunogenicity of three different dose levels of an experimental recombinant influenza HA protein vaccine to a standard...
dose escalationtrivalentrhastudyelderly
https://clinicaltrials.med.nyu.edu/cancer/clinicaltrial/1362/phase-1-first-in-human/?qd=34627423
A Phase 1 First-in Human Multi-Center Open Label Dose-Escalation Study to Determine the Safety...
New life-saving treatments for Urothelial Carcinoma, solid tumors in clinical trial on A Phase 1 First-in Human Multi-Center Open Label Dose-Escalation Study...
dose escalationthe safetyphasefirsthuman
https://digitalcommons.providence.org/publications/9135/
"A secukinumab dose-escalation study in patients with ankylosing spondy" by Atul Deodhar, Alan J...
Objective: To investigate the clinical response at week 52 in patients with ankylosing spondylitis (AS) who received secukinumab 300 vs 150 mg after inadequate...
dose escalationin patientsstudyatulalan
https://pure.fujita-hu.ac.jp/en/publications/phase-i-dose-escalation-clinical-trial-of-hf10-oncolytic-herpes-v/
Phase I Dose-escalation Clinical Trial of HF10 Oncolytic Herpes Virus in 17 Japanese Patients with...
phase idose escalationclinical trialherpes virusjapanese
https://multimedia.asrs.org/media/a-phase-1-multicenter-prospective-open-label-dose--22856
A Phase 1, Multicenter, Prospective, Open-Label, Dose Escalation Study of EYP-1901, a Tyrosine...
dose escalationphaseprospectiveopenlabel
https://researchers.westernsydney.edu.au/en/publications/phase-i-dose-escalation-study-to-determine-the-safety-tolerabilit/
Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and...
phase idose escalationthe safetystudydetermine
https://www.ijpsonline.com/abstract/a-phase-i-dose-escalation-study-of-apatinib-combinated-with-docetaxel-as-secondline-therapy-for-advanced-gastric-carcino-4261.html
A Phase I Dose Escalation Study of Apatinib Combinated with | 4261
A bi-monthly Journal, which publishes original research works that contributes significantly to further the scientific knowledge in Pharmaceutical Sciences
phase idose escalationstudy
https://www.canceropole-est.org/la-recherche-au-sein-du-canceropole-est/annuaires/publications-scientifiques/detail/?id=28231
A phase I dose escalation study using simultaneous integrated-boost IMRT with temozolomide in...
phase idose escalationstudyusingsimultaneous
https://courageousparentsnetwork.org/videos/clinical-trials-dose-escalation-phase-by-phase/
Clinical Trials: Dose escalation, Phase by Phase - Courageous Parents Network
clinical trialsdose escalationphasecourageousparents
https://scholars.houstonmethodist.org/en/publications/treatment-of-aspirin-resistant-patients-with-omega-3-fatty-acids-/
Treatment of Aspirin-Resistant Patients With Omega-3 Fatty Acids Versus Aspirin Dose Escalation -...
fatty acidsdose escalationtreatmentaspirinresistant
https://www.clinrol.com/study/170
A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of...
This study evaluates AZD8421 alone and with targeted anti-cancer drugs in ER+HER2- advanced breast cancer and metastatic ovarian cancer patients.
dose escalationthe safetyfirsthumanexpansion
https://amportal.astro.org/sessions/ss-31-21561/phase-i-pre-operative-single-fraction-dose-escalation-ablative-stereotactic-partial-breast-ir-106418
Phase I Pre-Operative Single Fraction Dose Escalation Ablative Stereotactic Partial Breast...
phase idose escalationpreoperativesingle
https://www.surveymonkey.com/r/DQD3V7W
Dose escalation in prostate cancer Survey
dose escalationprostate cancersurvey
https://adisinsight.springer.com/trials/700392707?error=cookies_not_supported&code=7baf86e5-90f0-436c-8393-58345c6cb976
A Randomized, Double-Blind, Placebo-Controlled, Dose Escalation Study of TRX-100 Tablets Evaluating...
This is a Phase 1b, randomized, double-blind, placebo-controlled, dose escalation study of TRX-100 tablets evaluating the safety, pharmacokinetics, and food
double blinddose escalationplacebocontrolledstudy
https://www.dana-farber.org/clinical-trials/19-467
A Phase 1/2, Open-label, Dose-Escalation and Dose-Expansion Cohort Study of SNDX-5613 in Patients...
Phase 1 dose escalation will determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of revumenib in participants with acute leukemia....
dose escalationcohort studyin patientsphaseopen
https://christie.openrepository.com/entities/publication/9f7f235e-ef8f-4cc0-a40f-fe0eaff5643d
383P A phase I dose-escalation study of the novel peptide ALM201 in patients (pts) with advanced...
phase idose escalationthe novelin patientsstudy
https://www.avera.org/research-and-clinical-trials/clinical-trials/detail/?id=185
MER-XMT-1660-1: A Phase 1, First-in-Human, Dose Escalation and Expansion, Multicenter Study of...
A Study of XMT-1660 in Solid Tumors
dose escalationmerphasefirsthuman
https://scholars.duke.edu/grant/274535
Scholars@Duke grant: A Phase II multicenter, open-label, single-arm dose escalation study of...
phase iisingle armdose escalationscholarsduke
https://visualping.io/pages/blu-5937-dose-escalation-in-chronic-cough-clinical-trial-alerts-4961392
BLU-5937 Dose Escalation in Chronic Cough Clinical Trial: Get alerts for the latest updates -...
See the latest updates to BLU-5937 Dose Escalation in Chronic Cough Clinical Trial. Subscribe for free to get alerts when changes are detected to BLU-5937 Dose...
for the latestdose escalationchronic coughclinical trialget alerts
https://www.prnewswire.com/news-releases/zhongze-therapeutics-announces-successful-completion-of-the-first-in-human-dose-escalation-study-of-zz6398-in-healthy-volunteers-301515620.html?tc=eml_cleartime
Zhongze Therapeutics Announces Successful Completion Of The First-In-Human Dose Escalation Study of...
/PRNewswire/ -- Zhongze Therapeutics, a clinical stage biotech company focused on the discovery, development and commercialization of innovative and...
the firstdose escalationtherapeuticsannouncessuccessful
https://scholars.uky.edu/en/publications/a-multicenter-phase-12a-dose-escalation-study-of-the-antioxidant-/fingerprints/
A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin e...
dose escalationthe antioxidantphasestudymoiety
https://www.knowcancer.com/cancer-trials/NCT01014936/
First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor EMD 1214063 in Subjects With Advanced...
This is a an open-label, dose-escalation, first-in-man (FIM) study designed to explore EMD 1214063, in patients with advanced solid tumors who have not
dose escalationfirstmantrialmet
https://www.epistemonikos.org/en/documents/cb02aff319d7732930ef2b4a533fc1f530ae91db
Chinese Multiple Dose Escalation (MDE) High Dose Study
A Phase 1 Randomized, Double-blinded, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Cotadutide in Overweig...
dose escalationchinesemultiplemdehigh
https://forums.mhra.gov.uk/showthread.php?1734-Suitability-of-targeted-SDV-of-data-collated-into-the-dose-escalation-interim-report&s=990f87dd17cc715be8ce6ece5103e310
Suitability of targeted SDV of data collated into the dose escalation interim report
My questions is regarding how to interpret the MHRA recommendation (Grey guide section 12.6.2) that there should be a clear quality control (QC) process to...
targeted sdvthe doseinterim reportsuitabilitydata
https://fis.tu-dresden.de/portal/de/publications/onestrength-dose-escalation-of-house-dust-mite-depot-product-for-subcutaneous-immunotherapy-is-safe-and-tolerable(5f4c8596-a18d-4560-b0c2-eb01b493fb30).html
One-strength dose escalation of house dust mite depot product for subcutaneous immunotherapy is...
dose escalationhouse dustonestrengthmite
https://lifestyle.all80sz1063.com/story/174412/salubris-biotherapeutics-presents-phase-1-2-dose-escalation-and-expansion-cohort-data-for-jk06-5t4-targeted-antibody-drug-conjugate-at-the-american-association-for-cancer-research-annual-meeting/
Salubris Biotherapeutics Presents Phase 1/2 Dose Escalation and Expansion Cohort Data for JK06,...
dose escalationbiotherapeuticspresentsphaseexpansion
https://researchworks.creighton.edu/esploro/outputs/journalArticle/Phase-I-Three-Dimensional-Conformal-Radiation-Dose/991006262305902656
Phase I Three-Dimensional Conformal Radiation Dose Escalation Study in Newly Diagnosed...
Mar 1, 2009 - To evaluate in a Phase I trial the feasibility and toxicity of dose-escalated three-dimensional conformal radiotherapy (3D-CRT) concurrent with chemotherapy in...
phase ithree dimensionaldose escalationnewly diagnosedradiation
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2019.00531/full
Frontiers | Feasibility of Dose Escalation in Patients With Intracranial Pediatric Ependymoma
Background and purposePediatric ependymoma carries a dismal prognosis, mainly owing to local relapse within RT fields. The current prospective European appro...
dose escalationin patientsfrontiersfeasibilitypediatric
https://checkorphan.org/clinicaltrial/safety-and-dose-escalation-study-of-an-adeno-associated-viral-vector-for-gene-transfer-in-hemophilia-a-participants/
Safety and Dose Escalation Study of an Adeno-Associated Viral Vector for Gene Transfer in...
dose escalationviral vectorgene transfersafetystudy
https://repository.icr.ac.uk/items/7177c11c-d472-4f8b-8cd6-12f078eab40a
Clinical Benefit of Ripretinib Dose Escalation After Disease Progression in Advanced...
BACKGROUND: Ripretinib 150 mg once daily (QD) is indicated for advanced gastrointestinal stromal tumors (GISTs) as at least fourth-line therapy. In INVICTUS,...
dose escalationdisease progressionclinicalbenefitripretinib
https://pubmed.ncbi.nlm.nih.gov/26531095/
Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on...
This clinical trial was registered on clinicaltrials.gov [NCT00908297] on May 21, 2009.
dose escalationcoenzymestudyhemodialysispatients
https://app.quri.ai/trials/NCT06541639/evm16cx01-first-in-human-dose-escalation-and-expansion-study
EVM16CX01: First-in-Human, Dose-Escalation, and Expansion Study Evaluating the Safety,...
Connect with this clinical trial through Quri.ai's free matching service. EVM16CX01: First-in-Human, Dose-Escalation, and Expansion Study Evaluating the...
dose escalationthe safetyfirsthumanexpansion
https://jdc.jefferson.edu/medoncfp/57/
"Phase I dose-escalation study of the mTOR inhibitor sirolimus and the " by Haeseong Park, Ignacio...
Preclinical models suggest that histone deacetylase (HDAC) and mammalian target of rapamycin (mTOR) inhibitors have synergistic anticancer activity. We...
phase idose escalationand bystudymtor
https://cancer.osu.edu/for-patients-and-caregivers/learn-about-cancers-and-treatments/innovation-at-the-james/clinical-trials/find-a-clinical-trial/a-phase-iib-openlabel-dose-escalation
A Phase I/Ib Open-Label, Dose Escalation, First-in-Human Study to Evaluate the Safety,...
A Phase I/Ib Open-Label, Dose Escalation, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-leukemic Activity...
phase idose escalationhuman studythe safetyib
https://www.page-meeting.org/Abstracts/informative-study-designs-the-value-of-within-subject-dose-escalation-in-the-espresso-design/
Informative study designs: The value of within-subject dose-escalation in the 'Espresso design'
Oct 21, 2025 - Poster: Methodology - Study Design - Informative study designs: The value of within-subject dose-escalation in the 'Espresso design'
study designsthe valuedose escalationinformativewithin
https://her2support.org/vbulletin/showthread.php?s=10f677107545a79afd337db8730a3deb&p=310524
Phase I Dose-escalation Trial of ARRY-380 in Combination With Trastuzumab in Particip - HER2...
Phase I Dose-escalation Trial of ARRY-380 in Combination With Trastuzumab in Particip Clinical Trials
phase idose escalationtrialarrycombination
https://siidon.guttmann.com/es/registro/randomized-dose-escalation-trial-elamipretide-adults-primary-mitochondrial-myopathy
Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy. |...
dose escalationmitochondrial myopathytrialadultsprimary
https://aesnet.org/abstractslisting/a-phase-2-dose-escalation-study-of-levetiracetam-in-the-treatment-of-neonatal-seizures-preliminary-results
a phase 2 dose escalation study of levetiracetam in the treatment of neonatal seizures: preliminary...
dose escalationthe treatmentphasestudylevetiracetam
https://pure.psu.edu/en/publications/phase-i-dose-escalation-study-of-temsirolimus-in-combination-with/
Phase I dose escalation study of temsirolimus in combination with metformin in patients with...
phase idose escalationstudycombinationmetformin
https://www.biospace.com/magenta-therapeutics-voluntarily-pauses-the-mgta-117-phase-1-2-dose-escalation-clinical-trial-to-investigate-drug-safety
Magenta Therapeutics Voluntarily Pauses the MGTA-117 Phase 1/2 Dose-Escalation Clinical Trial to...
Jan 25, 2023 - Magenta Therapeutics (Nasdaq: MGTA) today announced that the latest participant dosed at the Cohort 3 level (0.08 mg/kg) in the ongoing MGTA-117 Phase 1/2...
dose escalationclinical trialmagentatherapeuticspauses
https://www.oncolink.org/oncolink-library/journal-scans/non-small-cell-lung-cancer/toxicity-and-outcome-results-of-rtog-93-11-a-phase-i-ii-dose-escalation-study-using-three-dimensional-conformal-radiotherapy-in-patients-with-inoperable-non-small-cell-lung-carcinoma
Toxicity and Outcome Results of RTOG 93-11: A Phase I-II Dose-Escalation Study Using...
OncoLink, the Web's first cancer resource,provides comprehensive information on coping with cancer, cancer treatments, cancer research advances, continuing...
results ofphase idose escalationtoxicityoutcome
https://www.texasoncology.com/clinical-trials/05377996-A-Phase-1-First-in-Human-Dose-Escalation-and-Expansion-Multicenter-Study-of-XMT-1660-in-Par
A Phase 1, First-in-Human, Dose Escalation and Expansion, Multicenter Study of XMT-1660 in...
Learn more about Phase I Clinical Trial for Solid Tumors at Texas Oncology.
dose escalationphasefirsthumanexpansion
https://childrens.uvahealth.com/clinical-trials/trial/302054
Clinical Trials | A Phase 1, Open-Label, Dose-Escalation Study Evaluating the Safety, Tolerability,...
clinical trialsdose escalationthe safetyphaseopen
https://publicatt.unicatt.it/handle/10807/28445
A phase I dose-escalation study (iside-bt-1) of accelerated imrt with temozolomide in patients with...
phase idose escalationin patientsstudyiside
https://iris.hunimed.eu/handle/11699/10484
SBRT Dose Escalation Phase II Study for Liver Metastases Using Volumetric Modulated Arc Therapy...
dose escalationphase iiliver metastasesarc therapystudy
https://researchinformation.umcutrecht.nl/en/publications/a-phase-i-dose-escalation-study-of-two-cycles-carboplatin-olapari/
A Phase I dose-escalation study of two cycles carboplatin-olaparib followed by olaparib monotherapy...
phase idose escalationstudytwocycles
https://www.froedtert.com/clinical-trials/multicenter-phase-1-open-label-dose-escalation-and-expansion-study-azd0486?f%5B0%5D=category%3A27001&f%5B1%5D=condition%3A32661&f%5B2%5D=sub_category%3A16086&f%5B3%5D=sub_category%3A16091&f%5B4%5D=sub_category%3A16096
A Multicenter, Phase 1, Open-Label, Dose-Escalation and Expansion Study of AZD0486, a Bispecific...
The study drug, TNB-486, is a bispecific antibody. An antibody is a Y shaped protein used by your body's immune system to identify and destroy natural foreign...
dose escalationphaseopenlabelexpansion
https://www.hmpgloballearningnetwork.com/site/rheum/news/start-low-go-slow-dose-escalation-allopurinol
Start-Low Go-Slow Dose Escalation of Allopurinol
Researchers identified which patients with gout may require longer periods of prophylaxis when initiating treatment. Gout News
start lowgo slowdose escalationallopurinol
https://decentrialz.com/clinical-trials/NCT00000645/phase-dose-escalation-study-synthetic-hypericin-00000645
A Phase I Dose Escalation Study of Synthetic Hypericin in HIV-Infected Patients With Less Than 300...
Hypericin is unlike other drugs presently being used to treat AIDS patients. Hypericin shows anti-HIV activity in test tube experiments. Each group of eight...
phase idose escalationless thanstudysynthetic
https://www.clinicaltrialsarena.com/news/sellas-aml-therapy/
SELLAS closes safety assessment in dose escalation trial of AML
Apr 21, 2023 - SELLAS has concluded the safety assessment stage of the highest dose cohort of its Phase l dose escalation trial of GFH009.
safety assessmentdose escalationclosestrialaml
https://www.allclinicaltrials.com/study/NCT06169371?searchMetadata=eyJjb25kaXRpb24iOiJicmVhc3QtY2FuY2VyIiwic2VhcmNoQ2FyZFBvc2l0aW9uIjozfQ%3D%3D
Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)
This is a post-marketing single arm, phase IV trial in which patients with high-risk early-stage HR+HER2- breast cancer will receive adjuvant abemaciclib in...
dose escalationabemaciclibmaintainintensityade