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https://openrespiratorymedicinejournal.com/VOLUME/14/PAGE/87/FULLTEXT/ Respiratory Candida in Patients with Bronchitis, Mucus Plugging, and Atelectasis Respiratory Candida in Patients with Bronchitis, Mucus Plugging, and Atelectasis in patients respiratory candida bronchitis mucus https://www.mediasphera.ru/issues/kardiologiya-i-serdechno-sosudistaya-khirurgiya/2012/4/031996-63852012416 Comparative analysis of results of mono- and bipolar radiofrequent ablation in patients with... Zheleznev SI, Bogachev-Prokof'ev AV, Pivkin AN, Nazarov VM, Laviniukov SO, Ivanov IV, Emeshkin MI, Karas'kov AM. Comparative analysis of results of mono- and... comparative analysis in patients results mono bipolar https://www.eurjbreasthealth.com/articles/the-relationship-between-bone-mineral-density-and-estrogen-receptor-positivity-in-patients-with-breast-cancer/doi/tjbh.2016.2961 The Relationship between Bone Mineral Density and Estrogen Receptor Positivity in Patients with... The Relationship between Bone Mineral Density and Estrogen Receptor Positivity in Patients with Breast Cancer - European Journal of Breast Health bone mineral density the relationship estrogen receptor positivity https://digitalscholar.lsuhsc.edu/som_facpubs/4412/ "An Investigation of Surgical Feeding Access in Patients With Remote Ba" by Renee Rumsey, Corbin... BackgroundPatients with a history of bariatric surgery present a challenge in obtaining surgical feeding access due to altered gastrointestinal anatomy after... an investigation with remote surgical feeding access https://www.gjms.com.pk/index.php/journal/article/view/1063/pdf EFFECT OF METHIMAZOLE ON SERUM CONCENTRATIONS OF OXIDATIVE STRESS MARKERS IN PATIENTS WITH... EFFECT OF METHIMAZOLE ON SERUM CONCENTRATIONS OF OXIDATIVE STRESS MARKERS IN PATIENTS WITH HYPERTHYROIDISM IN THE POPULATION OF KUTAHYA CITY, TURKEY oxidative stress in patients effect methimazole serum https://institutionalrepository.aah.org/auroragme/225/ "The efficacy and safety of neoadjuvant immunotherapy in patients with " by Sakti Chakrabarti,... By Sakti Chakrabarti, Marie Parish, Carrie Peterson, et al., Published on 02/01/23 in patients efficacy safety immunotherapy sakti https://iris.unical.it/handle/20.500.11770/378045 Drug-eluting stent implantation in patients with acute coronary syndrome - the Activity of... acute coronary syndrome in patients drug stent implantation https://www.oaepublish.com/articles/2394-4722.2018.12 Secondary malignancy estimation in patients after mastectomy and adjuvant therapy Aim: Secondary malignancy estimation after radiotherapy of post mastectomy patients is becoming an important subject for comparative treatment planning. The... in patients adjuvant therapy secondary malignancy estimation https://avesis.erciyes.edu.tr/yayin/2c981363-4978-42c8-813b-db712795744e/effects-of-short-and-long-term-lithium-treatment-on-kidney-functioning-in-patients-with-bipolar-mood-disorder Effects of short- and long-term lithium treatment on kidney functioning in patients with bipolar... long term in patients effects short lithium https://ascopost.com/news/january-2021/immune-response-to-covid-19-reduced-in-patients-with-hematologic-malignancies-vs-solid-tumors/ Immune Response to COVID-19 Reduced in Patients With Hematologic Malignancies vs Solid Tumors - The... Patients with hematologic malignancies varied in their immune response to COVID-19, and some struggled to clear the infection, according to new research... immune response in patients hematologic malignancies solid tumors covid https://pmc.ncbi.nlm.nih.gov/articles/PMC4906200/ Clinical Distinctness of Allergic Rhinitis in Patients with Allergy to Molds - PMC Introduction. Molds are a very diverse group of allergens. Exposure and sensitization to fungal allergens can promote the development and worsening of allergic... allergic rhinitis clinical patients allergy molds https://www.onescdvoice.com/news-meeting/bluebird-bio-presents-new-data-hgb-205-study-lentiglobintm-drug-product-patients-transfusion-dependent-%CE%B2-thalassemia-tdt-severe-sickle-cell-disease-american-society/ bluebird bio Presents New Data from HGB-205 Study of LentiGlobinTM Drug Product in Patients with... get connected to the best sources of Sickle Cell Disease information and support online, all for free. bluebird bio new data drug product in patients presents https://www.xiahepublishing.com/2310-8819/JCTH-2024-00316 Development and Validation of a New Prognostic Model for Predicting Survival Outcomes in Patients... Early determination of prognosis in patients with acute-on-chronic liver failure (ACLF) is crucial for optimizing treatment options and liver allocation. This... development and validation survival outcomes in patients new model https://www.iris.unicz.it/handle/20.500.12317/74999 An investigation of taste alteration in patients undergoing cancer chemotherapy an investigation cancer chemotherapy taste alteration patients https://scholars.houstonmethodist.org/en/publications/coronary-artery-calcium-scoring-for-cardiovascular-risk-assessmen/fingerprints/ Coronary artery calcium scoring for cardiovascular risk assessment in patients with inflammatory... calcium scoring cardiovascular risk coronary artery assessment https://research.ucc.ie/en/publications/prevalence-of-pks-bacteria-and-enterotoxigenic-bacteroides-fragil/ Prevalence of pks + bacteria and enterotoxigenic Bacteroides fragilis in patients with colorectal... in patients prevalence pks bacteria colorectal https://ctv.veeva.com/study/study-to-evaluate-safety-and-efficacy-of-dapagliflozin-in-patients-with-type-2-diabetes-mellitus-age Study to Evaluate Safety and Efficacy of Dapagliflozin in Patients With Type 2 Diabetes Mellitus... A trial of patients aged 10-24 years with type 2 diabetes mellitus to evaluate the comparative efficacy and safety between dapagliflozin and Placebo. in patients diabetes mellitus study evaluate safety https://publish.kne-publishing.com/index.php/jost/article/view/15510 Total Knee Arthroplasty in Patients with Concomitant Low Back Pain, Its Effects on Pain, Functional... low back pain total knee arthroplasty patients https://irjournal.org/journal/view.php?viewtype=pubreader&number=1052 Live-attenuated vaccination in patients with inflammatory bowel disease while continuing or after... inflammatory bowel disease live vaccination patients continuing https://journals.eco-vector.com/1994-9480/article/view/118663 COMPARATIVE ANALYSIS OF MICROHAEMODYNAMICS AND VASOMOTOR ENDOTHELIAL FUNCTION IN PATIENTS WITH... COMPARATIVE ANALYSIS OF MICROHAEMODYNAMICS AND VASOMOTOR ENDOTHELIAL FUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE AND APPARENTLY HEALTHY INDIVIDUALS IN... comparative analysis in patients function https://repub.eur.nl/pub/13194 RePub, Erasmus University Repository: Myeloperoxidase Serum Levels Predict Risk in Patients With... in patients erasmus university repository serum https://www.spandidos-publications.com/10.3892/or.16.1.191 A single-center report on clinical features and treatment response in patients with intestinal T... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. single center clinical features report treatment response https://staff-old.najah.edu/iyad-ali/published-research/diabetes-mellitus-patients-schizophrenia-west-bank-palestine Diabetes Mellitus in Patients with Schizophrenia in West-Bank, Palestine | An-Najah Staff diabetes mellitus in patients with schizophrenia west bank palestine https://www.e-arm.org/journal/view.php?number=639&viewtype=pubreader Risk Factors for Delirium During Acute and Subacute Stages of Various Disorders in Patients... Annals of Rehabilitation Medicine (ARM) is an international, peer-reviewed open access journal which aims to share up-to-date knowledge dedicated to the... risk factors stages of in patients delirium acute https://scholarlyworks.corewellhealth.org/corewellhealth_west_research_posters/106/ "The Impact of Sternal Fractures in Patients with Blunt Thoracic Injury" by Patrick Renner,... Traumatic sternal fractures present a clinical challenge to risk stratification and management strategies. An increasing burden of rib, clavicle, and scapula... the impact in patients thoracic injury fractures blunt https://mjms.mums.ac.ir/article_14605.html?lang=en Effectiveness of Emotional Therapy on Reducing Anxiety and Depression in Patients with Multiple... Introduction: The purpose of this study was to determine the effect of emotion-focused therapy on the reduction of anxiety and depression in patients with... anxiety and depression in patients effectiveness emotional therapy https://research.hanze.nl/nl/publications/prognostic-factors-for-duration-of-sick-leave-in-patients-sick-li-2/ Prognostic factors for duration of sick leave in patients sick listed with acute low back pain: an... low back pain sick leave factors duration patients https://adisinsight.springer.com/trials/700257356?error=cookies_not_supported&code=1232999e-deaf-4fd9-b52a-80dd413dcb0a Effect of dofetilide in patients with atrial fibrillation who were not able to convert sinus... This study investigated the effect of dofetilide in patients with atrial fibrillation who were not able to convert sinus rhythms. in patients atrial fibrillation effect able convert https://repository.icr.ac.uk/items/865fe4b9-885a-4c85-8b7d-d0d95326bcba Identification and assessment of health-related quality of life issues in patients with sporadic... PURPOSE: Sporadic desmoid-type fibromatosis (DTF) is a rare, chronic, non-metastasising, disease of the soft tissues. It is characterised by local invasive and... identification and assessment health related life issues in patients quality https://blogs.nejm.org/cardioexchange/2012/07/10/drug-eluting-stents-often-used-in-patients-at-low-risk-for-restenosis/ Drug-Eluting Stents Often Used in Patients at Low Risk for Restenosis | CardioExchange used in drug stents often patients https://www.natera.com/resource-library/poster/circulating-tumor-dna-monitoring-in-patients-with-advanced-urothelial-carcinoma-treated-with-enfortumab-vedotin-pembrolizumab/ Circulating tumor DNA monitoring in patients with advanced urothelial carcinoma treated with Enfortu Reyes KR, Jindal T, Mitchell B, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025. in patients urothelial carcinoma tumor dna monitoring https://irf.fhnw.ch/entities/publication/8c0c9064-d8d4-4689-96dd-f479c587b2e2/full?back=true Association of comorbidities with clinical outcomes in patients after acute myocardial infarction clinical outcomes myocardial infarction association comorbidities patients https://pure.fujita-hu.ac.jp/en/publications/a-pilot-randomized-study-of-the-neutrophil-elastase-inhibitor-siv/ A pilot randomized study of the neutrophil elastase inhibitor, Sivelestat, in patients undergoing... randomized study in patients pilot elastase inhibitor https://www.mdpi.com/2077-0383/11/18/5310 Prognostic Significance of Organ-Specific Metastases in Patients with Metastatic Upper Tract... Background: Existing data on metastatic upper tract urothelial carcinoma (mUTUC) are limited. In this study, we investigated the prognostic value of... in patients upper tract significance organ specific https://andrewbrowns.com/patient-resources/article/2658669204/implant-delivers-chemo-directly-to-brain-in-patients-battling-brain-tumors Implant Delivers Chemo Directly to Brain in Patients Battling Brain Tumors | Andrew Brown's Drug... Looking for a local pharmacy with a personal touch? Andrew Brown's Drug Store offers traditional quality service with modern-day conveniences. Try us today! in patients andrew brown implant delivers chemo https://yoda.yale.edu/article-feature/association-of-race-and-survival-in-patients-treated-with-apalutamide-pooled-analysis-of-two-phase-3-trials/ Association of race and survival in patients treated with apalutamide: Pooled analysis of two phase... in patients two phase association race survival https://www.cirm.ca.gov/cirm-trial/ab-2100-an-integrated-circuit-t-cell-therapy-in-patients-with-recurrent-clear-cell-renal-cell-carcinoma-ccrcc-2/ AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell... integrated circuit cell therapy ab patients recurrent https://www.walshmedicalmedia.com/abstract/chromosomal-qheterochromatin-polymorphism-in-patients-with-alimentary-obesity-23008.html Chromosomal Q-Heterochromatin Polymorphism in Patients with | 23008 Variability of the amount of chromosomal Q-heterochromatin regions (Q-HRs) was studied in individuals with alimentary obesity and in controls from two... in patients q heterochromatin polymorphism https://www.sciencedaily.com/releases/2011/11/111130120112.htm Researchers develop a way to monitor engineered blood vessels as they grow in patients |... New research describes how by using magnetic resonance imaging and nanoparticle technology, scientists can monitor the growth of laboratory-engineered blood... a way blood vessels in patients researchers develop https://iris.uniupo.it/handle/11579/176227 Dapagliflozin improves myocardial flow reserve in patients with type 2 diabetes: the DAPAHEART... in patients improves flow reserve type https://scholarshare.temple.edu/entities/publication/f2d99b5b-aad5-487d-aa5c-580b53ee1acb Dual Antiplatelet Therapy in Patients Aged 75 Years and Older with Coronary Artery Disease: A... Objectives. This systematic review and meta-analysis evaluates the safety and efficacy of dual antiplatelet therapy (DAPT) in elderly patients with acute... coronary artery disease in patients dual antiplatelet therapy https://wiredspace.wits.ac.za/items/f41b20fe-6bd5-4422-bc80-bbab1042a637 Outcome of HAART in patients with tuberculosis in the Themba Lethu clinical cohort Introduction: The burden of disease due to HIV/AIDS and tuberculosis remains great for many countries around the world. Continuing attention must be devoted to... in patients outcome haart tuberculosis themba https://clinicaltrials.med.nyu.edu/cancer/clinicaltrial/1630/phase-12-study-regn5678/?qd=39378437 A PHASE 1/2 STUDY OF REGN5678 (ANTI-PSMAXCD28) WITH OR WITHOUT CEMIPLIMAB (ANTI-PD-1) IN PATIENTS... New life-saving treatments for Prostate Cancer in clinical trial on A PHASE 1/2 STUDY OF REGN5678 (ANTI-PSMAXCD28) WITH OR WITHOUT CEMIPLIMAB (ANTI-PD-1) IN... in patients phase study anti without https://www.itmedicalteam.pl/articles/physical-activity-assessment-in-patients-with-multiple-sclerosis-107697.html Physical Activity Assessment in Patients with Multiple Sclerosis Multiple sclerosis (MS) is on the second place after epilepsy in the young people fourth place among the neurological diseases of central nervous syste.. physical activity in patients multiple sclerosis assessment https://www.epistemonikos.org/en/documents/68a69e96749b9c1d90cd8442a45c139d899b2aae Phase I/II clinical trial for the evaluation of vaccine candidate CIGB-230 in patients with chronic... INTERVENTION: The study will involve four groups of treatment (A, B, C y D), 15 individuals in each one, with 8 administrations, four weeks interval, through... phase i clinical trial for the ii evaluation https://pure.skku.edu/en/publications/value-of-adding-sonoelastography-to-conventional-ultrasound-in-pa/ Value of adding sonoelastography to conventional ultrasound in patients with congenital muscular... in patients value adding sonoelastography conventional https://www.311institute.com/dna-based-cancer-vaccine-triggers-immune-attack-on-cancers-in-patients/ DNA based cancer vaccine triggers immune attack on cancers in patients - 311 Institute May 21, 2021 - Cancer is a stone cold killer, and we need sophisticated new tools in our arsenal to eradicate it. cancer vaccine dna based triggers immune https://www.journal-imab-bg.org/statii-08/vol14book1p89-94.htm NTProBNP AND HRV AND OUTCOME IN PATIENTS WITH HEART FAILURE WITH REDUCED VS. PRESERVED SYSTOLIC... JofIMAB 2008; 14(1):72-75, Journal of IMAB - Annual Proceeding (Scientific Papers), Subject Collection: Medicine in patients heart failure hrv outcome reduced https://checkorphan.org/clinicaltrial/a-study-to-investigate-the-effectiveness-of-atezolizumab-in-patients-with-inoperable-locally-advanced-or-metastatic-urothelial-carcinoma-of-the-urinary-tract-announce/ A Study to Investigate The Effectiveness Of Atezolizumab In Patients With Inoperable... a study to investigate effectiveness patients https://archivesofrheumatology.org/index.php/pub/article/view/1125 Self-Reported Medication Adherence in Patients With Ankylosing Spondylitis: The Role of Illness... Objectives: This study aims to investigate medication adherence in Turkish patients with ankylosing spondylitis (AS) and analyze the related factors for... medication adherence in patients ankylosing spondylitis role of self https://unipv.unifind.cineca.it/resource/item/26697?language=en-US UNIFIND - UNIPV -Reduced plasma apelin levels in patients with autistic spectrum disorder Unifind is a portal where you can discover the expertise within a university by searching among experts, courses, professions, people, publications, and... autistic spectrum disorder in patients reduced plasma levels https://www.cochrane.org/evidence/CD011719_effects-remote-ischaemic-preconditioning-patients-undergoing-coronary-artery-bypass-graft-surgery-or Effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass graft... coronary artery bypass in patients effects remote preconditioning https://researchinformation.umcutrecht.nl/en/publications/shocks-personality-and-anxiety-in-patients-with-an-implantable-de/ Shocks, personality, and anxiety in patients with an implantable defibrillator - University Medical... in patients implantable defibrillator shocks personality anxiety https://research.vu.nl/en/publications/red-flags-to-screen-for-malignancy-and-fracture-in-patients-with-/ Red flags to screen for malignancy and fracture in patients with low back pain: systematic review -... low back pain red flags systematic review screen malignancy https://researchworks.creighton.edu/esploro/outputs/journalArticle/Predictors-of-long-term-myelopathy-relief-in/991006268797102656 Predictors of long-term myelopathy relief in patients with moderate to severe cervical spondylotic... May 1, 2026 - Surgery for cervical spondylotic myelopathy (CSM) aims to halt disease progression. However, some patients will also ultimately note relief from their... long term in patients predictors myelopathy relief https://www.acc.org/Latest-in-Cardiology/Clinical-Trials/2010/02/23/19/03/Enoximone-Exercise Multicenter Trial of Oral Enoximone in Patients with Moderate to Moderately Severe Congestive Heart... in patients trial oral moderate severe https://www.sahealth.sa.gov.au/wps/wcm/connect/Public+Content/SA+Health+Internet/Services/Outpatients/CPC/specialities/Endocrinology/Hypoglycaemia+in+Patients+without+Known+Diabetes+Mellitus+adult+CPC Hypoglycaemia in Patients Without Known Diabetes Mellitus - Adult CPC | SA Health Information to assist with decisions about referral into public specialist outpatient services for Hypoglycaemia in Patients without Known Diabetes Mellitus in... in patients diabetes mellitus hypoglycaemia without known https://www.clinrol.com/study/414 IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas | Clinrol This study evaluates IKS03, a CD19 antibody-drug conjugate, for safety, dosing, and efficacy in advanced B cell non-Hodgkin lymphoma patients. in patients advanced b cell non https://www.growkudos.com/publications/10.1080%25252F13816810.2019.1622021/reader Paradoxical response to carbonic anhydrase inhibitors in patients with intraretinal cystoid spaces... Intraretinal cystoid spaces (IRCS) are fluid-filled spaces seen in some retinal dystrophies and often treated with carbonic anhydrase inhibitors. We have shown... carbonic anhydrase inhibitors paradoxical response patients spaces https://www.natap.org/2014/AASLD/AASLD_137.htm Entecavir reduces the incidence of hepatocellular carcinoma in patients with chronic hepatitis B hepatocellular carcinoma chronic hepatitis incidence patients b https://www.joraldiagnosis.com/revista/article/view/360/475 Oral manifestations in patients with dengue. a forgotten and neglected disease. cross-sectional... in patients oral manifestations dengue forgotten https://almclinmed.ru/jour/article/view/1422/en_US Assessment of carotid arteries and brain matter in patients with isolated abnormal tortuosities and... Assessment of carotid arteries and brain matter in patients with isolated abnormal tortuosities and those combined with occlusion by computed tomography... in patients assessment carotid arteries brain https://research.aalto.fi/en/publications/metabolomics-of-synovial-fluid-and-infrapatellar-fat-pad-in-patie/ Metabolomics of Synovial Fluid and Infrapatellar Fat Pad in Patients with Osteoarthritis or... synovial fluid in patients metabolomics fat pad https://www.canceropole-est.org/la-recherche-au-sein-du-canceropole-est/annuaires/publications-scientifiques/detail/?id=30671 Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and... in patients versus placebo enable spironolactone https://publires.unicatt.it/it/publications/cross-reactivity-and-tolerability-of-imipenem-in-patients-with-de-7/ cross-reactivity and tolerability of imipenem in patients with delayed-type, cell-mediated... in patients cross reactivity delayed type https://nursing.usp-pl.com/index.php/Nursing/article/view/206/203 Study on Sleep Quality and Influencing Factors in Patients with Coronary Heart Disease | Li |... Study on Sleep Quality and Influencing Factors in Patients with Coronary Heart Disease coronary heart disease sleep quality in patients study influencing https://bioengineer.org/exploring-urinary-and-serum-prolactin-in-patients/ Exploring Urinary and Serum Prolactin in Patients Dec 14, 2025 - In a groundbreaking study published in BMC Endocrine Disorders, researchers have made significant strides in understanding the dynamics of prolactin levels in... in patients exploring urinary serum prolactin https://www.iris.unicampus.it/handle/20.500.12610/147 Angiogenic cytokines in patients undergoing antiviral treatment for chronic hepatitis C virus... chronic hepatitis c in patients antiviral treatment angiogenic cytokines https://aidevmd.com/effects-of-instrument-assisted-soft-tissue-mobilisation-in-patients-with-chronic-mechanical-low-back-pain-a-randomized-control-trial/ Effects of instrument assisted soft tissue mobilisation in patients with chronic mechanical low... Feb 14, 2025 - Effects of Instrument-Assisted Soft Tissue Mobilisation on Chronic Low Back Pain Study Overview This study aimed to compare two treatment methods for managing c soft tissue in patients effects instrument assisted https://journal.uii.ac.id/JKKI/article/view/13627/pdf View of Relationship between thyroid hormone and lipid profile in patients with struma at the... thyroid hormone lipid profile in patients view relationship https://ar.iiarjournals.org/content/26/6B/4519 The Characterization of Gefitinib Sensitivity and Adverse Events in Patients with Non-small Cell... Background: Factors predicting gefitinib sensitivity and adverse events in non-small cell lung cancer (NSCLC) remain controversial. Patients and Methods:... adverse events in patients small cell characterization sensitivity https://digitalcommons.providence.org/publications/5662/ "Impact of Age on Outcomes in Patients With Cardiogenic Shock." by Manreet Kanwar, Katherine L... Background: Advanced age is associated with poor outcomes in cardiovascular emergencies. We sought to determine the association of age, use of support devices... in patients cardiogenic shock impact age outcomes https://www.emrap.org/episode/ema-2009-10/abstract4 EMA - Health Beliefs Toward Cardiovascular Risk Reduction In Patients Admitted To Chest Pain... EM:RAP is a monthly emergency medicine audio series full of CME and the latest reviews and perspectives. Get started today with some free CME. cardiovascular risk in patients chest pain ema health https://pure.psu.edu/en/publications/clinical-impact-of-baseline-chronic-kidney-disease-in-patients-un/ Clinical impact of baseline chronic kidney disease in patients undergoing transcatheter or surgical... chronic kidney disease clinical impact baseline patients surgical https://evidence.unboundmedicine.com/evidence/view/infoPOEMs/1314876/all/Iron_supplementation_may_be_beneficial_in_patients_with_heart_failure_and_iron_deficiency Iron supplementation may be beneficial in patients with heart failure and iron deficiency | EE+... Iron supplementation may be beneficial in patients with heart failure and iron deficiency answers are found in the EE+ POEM Archive powered by Unbound... may be in patients heart failure iron supplementation https://microbiol.crie.ru/jour/article/view/984/559 Detection of drug resistance mutations of hepatitis C virus in patients with failure of the... Detection of drug resistance mutations of hepatitis C virus in patients with failure of the treatment with direct acting antivirals hepatitis c virus drug resistance in patients detection mutations https://opencardiovascularmedicinejournal.com/VOLUME/8/PAGE/76/ Beta-blockers Associated with a Mortality Benefit in Patients with Systolic Dysfunction and... Beta-blockers Associated with a Mortality Benefit in Patients with Systolic Dysfunction and Elevated Serum Bilirubin beta blockers associated with in patients mortality benefit