https://pubmed.ncbi.nlm.nih.gov/30559476/
Microglia, the specialized innate immune cells of the CNS, play crucial roles in neural development and function. Different phenotypes and functions have been...
humanmicrogliaregionalheterogeneityphenotypes
https://pubmed.ncbi.nlm.nih.gov/15598982/
In eukaryotes, prereplication complexes (pre-RCs) containing ORC, Cdc6, Cdt1, and MCM2-7 are assembled on chromatin in the G1 phase. In S phase, when DNA...
replicationdependentdestructionlimitsdna
https://www.discovermagazine.com/can-a-single-cell-recognize-your-face-15607
UCLA's groundbreaking research discovers thinking cells in the human brain, potentially reshaping our understanding of cognition.
a singleyour facediscover magazinecellrecognize
https://www.the-scientist.com/spt-labtech-and-alithea-genomics-collaborate-to-automate-ultra-sensitive-single-cell-transcriptomic-workflows-73733
Nov 13, 2025 - Enables higher-throughput, cost effective single-cell sequencing
sptgenomicscollaborateautomateultra
https://pubmed.ncbi.nlm.nih.gov/37188816/
The main critical step in single-cell transcriptomics is sample preparation. Several methods have been developed to preserve cells after dissociation to...
the methodmethanolfixationchoicedroplet
https://pubmed.ncbi.nlm.nih.gov/39438660/?dopt=Abstract
Precision medicine in immune-mediated inflammatory diseases (IMIDs) requires a cellular understanding of treatment response. We describe a therapeutic atlas...
tumour necrosis factorsingle celllongitudinalatlasanti
https://pubmed.ncbi.nlm.nih.gov/25420068/?dopt=Abstract
The primary sensory system requires the integrated function of multiple cell types, although its full complexity remains unclear. We used comprehensive...
sensory neuronlarge scaleunbiasedclassificationtypes
https://elifesciences.org/articles/95628
A comprehensive description of gene expression and organisation in the cells that constitute the blood fluke larvae responsible for finding and invading its...
a singlecellatlasmiracidiumlarva
https://1cell.ai/solo/
1Cell SOLO enables easy, efficient single cell sample preparation for multi omic analysis, empowering translational and clinical research workflows.
single cellsolosampleprepmade
https://pubmed.ncbi.nlm.nih.gov/41417875/
Developing computational methods for single-cell drug response prediction deepens our understanding of tumor heterogeneity and uncovers resistance mechanisms...
domain adaptationsingle cellgraphbasedapproach
https://singlecell.creative-biolabs.com/
Creative Biolabs Single cell provides a comprehensive suite of single cell omics solutions to help our clients address the true complexities of various areas...
single cellcreative
https://zenodo.org/records/17023204
Method code for RoCK and ROI: a single-cell RNA-sequencing method with enhanced transcriptome information via targeted enrichment of transcripts and...
single cellmethodcoderockroi
https://pubmed.ncbi.nlm.nih.gov/25333837/
Single fraction total body irradiation (SFTBI) as part of a myeloablative preparative regimen in allogeneic hematopoietic stem cell transplantation (HSCT) for...
stem cell transplantlatetoxicitynovelallogeneic
https://pubmed.ncbi.nlm.nih.gov/37792582/
Oral squamous cell carcinoma of the gingivo-buccal region (OSCC-GB) is the most common cancer among men in India, and is associated with poor prognosis and...
single celloral cancertranscriptomicanalysisbuccal
https://www.mdpi.com/1996-1073/16/16/5932
The fuel cell with a ten-channel serpentine flow field has a low operating pressure drop, which is conducive to extended test operations and stable use....
a newsingle celldesignflowfield
https://elifesciences.org/for-the-press/265ec424/single-cell-asymmetries-control-how-groups-of-cells-form-3d-shapes-together
A new mathematical tool shows that altering one of two asymmetries in the properties of single cells controls how they organise into folded, biological shapes,...
single cellasymmetriescontrolgroupscells
https://www.illumina.com/products/by-type/sequencing-kits/library-prep-kits/single-cell-rna-prep.html
Accessible and highly scalable single-cell RNA-Seq solution for mRNA capture, barcoding, and library prep without complex workflows or microfluidics
single cellilluminarnaprepkits
https://www.businesswire.com/news/home/20220728005160/en/Ozette-Announces-%2426MM-in-Series-A-Funding-for-AI-Powered-Single-Cell-Immune-Discovery-Technology-that-Accelerates-Therapeutics-Across-Research-and-Development
Ozette Technologies, Inc. announces $26 million in Series A funding for AI-powered single-cell immune discovery technology.
series a fundingozetteannouncesaipowered
https://walter.hms.harvard.edu/publication/vrtis-et-al-2021-single-strand-dna-breaks-cause-replisome-disassembly-molecular-cell-81-1309-1318/
et alsingle stranddnabreakscause
https://pubmed.ncbi.nlm.nih.gov/41349540/
Chimeric antigen receptor (CAR) T cell therapies targeting B cell maturation antigen (BCMA) are transforming treatment for relapsed or refractory multiple...
single celllongitudinalatlaspredictoutcome
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1069379/full
Both gene expression and protein concentrations are regulated by genetic variants. Exploring the regulation of both eQTLs and pQTLs simultaneously in a conte...
candida albicanssingle cellgene expressionfrontiersintegration
https://www.frontiersin.org/journals/computer-science/articles/10.3389/fcomp.2021.734559/full
Single-cell methods are beginning to reveal the intrinsic heterogeneity in cell populations, arising from the interplay of deterministic and stochastic proce...
frontiersautomateddeeplineagetree
https://jsb-lab.org/publication/scdesign2-an-interpretable-simulator-that-generates-high-fidelity-single-cell-gene-expression-count-data-with-gene-correlations-captured/
high fidelitysingle cellsimulator
https://www.bioescalator.ox.ac.uk/news-and-events/news/ochre-bio-completes-human-liver-functional-genomics-and-single-cell-datasets-in-partnership-with-gsk
Ochre Bio, a biotechnology company developing RNA therapeutics for chronic liver disease, today announced the successful completion of the research phase of...
human liverfunctional genomicssingle cellochrebio
https://www.utmb.edu/scoa/news-and-events/2023/05/05/pepper-investigators-lecture-nir
A video is now available online for the Pepper Investigators Lecture on May 3, 2023, "Studies of Genome Organization at the Single-Cell Level," presented by...
new videosingle cellstudiesgenomeorganization
https://elifesciences.org/articles/86504/peer-reviews
The heterogeneity in molecule and function of three main cell types of smooth muscle cells, endothelial cells, and fibroblasts from both different anatomical...
peer reviewin asingle celltranscriptomeatlas
https://pubmed.ncbi.nlm.nih.gov/36303541/
Tumors are a class of diseases characterized by altered genetic information and uncontrolled growth. Sequencing technology provide researchers with a better...
single cell sequencingthe fieldadvancestechnology
https://www.cmu.edu/compbio/news/2018/neural-nets-supplant-marker-genes-in-analyzing-single-cell-rna-sequencing.html
Computer scientists at Carnegie Mellon University say neural networks and supervised machine learning techniques can efficiently characterize cells that have...
neural netssingle cellmarkergenesanalyzing
https://pubmed.ncbi.nlm.nih.gov/35817982/
Mapping chromatin loops from noisy Hi-C heatmaps remains a major challenge. Here we present DeepLoop, which performs rigorous bias correction followed by...
mapschromatininteractionssparseallele
https://www.telerik.com/forums/how-to-customize-the-cell-editor-to-bind-a-single-element
The following is traversal binding. The onDataBound method allows you to bind cells individually, similar to my following writing method of $("# spread...
how tothe cella singlecustomizeeditor
https://pubmed.ncbi.nlm.nih.gov/30078726/
Linking regulatory DNA elements to their target genes, which may be located hundreds of kilobases away, remains challenging. Here, we introduce Cicero, an...
single cellcicerocisregulatorydna
https://www.telerik.com/forums/put-the-cell-into-edit-mode-with-single-click
how to put selected row cell into edit mode with single click or selection. Currently, I have to click twice to have it in the edit mode. First click selects...
the cellputeditmodesingle
https://elifesciences.org/articles/91705v1
Single-cell sequencing and functional analysis identify T cells that can be useful for marker selection and cell therapy in uveal melanoma, a disease largely...
single cell sequencingpatientderivedxenograftsthree
https://nanoporetech.com/applications/investigations/single-cell-sequencing
Reveal more biology with single-cell nanopore sequencing: perform gene- and isoform-level expression analysis and identify variants in a single experiment....
single cell sequencingoxford nanopore technologies
https://www.cellanome.com/immunology
Comprehensive immune cell analysis platform. Study T-cell interactions, dendritic cells, and immunotherapy responses with real-time cellular dynamics tracking.
immune cellanalysissingleresearchplatform
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.1099271/full
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers globally, with significant cell heterogeneity and poor prognosis. Distant metasta...
single cellepithelial cellsfrontiersprofilingreveals
https://pubmed.ncbi.nlm.nih.gov/41352524/
Non-ischemic cardiomyopathy (NICM) is a devastating diagnosis with a wide array of phenotypes, ranging from mild cardiac hypertrophy to end-stage heart...
single celltranscriptomiclandscapeadultpediatric
https://pubmed.ncbi.nlm.nih.gov/35637521/
Tumors are complex tissues of cancerous cells surrounded by a heterogeneous cellular microenvironment with which they interact. Single-cell sequencing enables...
tumor cellsusing machineidentifyingsinglelevel
https://www.arxiv.org/abs/2310.12829
Abstract page for arXiv paper 2310.12829: A Microwell-Based Microfluidic Device for Single-Cell Trapping and Magnetic Field Gradient Stimulation
microfluidic devicesingle cellbased
https://pubmed.ncbi.nlm.nih.gov/35959412/
Heart failure represents a major cause of morbidity and mortality worldwide. Single-cell transcriptomics have revolutionized our understanding of cell...
single celltranscriptomicsrevealstypespecific
https://www.academia.edu/145733250/Lipid_stores_reveal_the_state_of_the_coral_algae_symbiosis_at_the_single_cell_level
Coral reefs worldwide are threatened by environmental stress. The observable decline in coral cover, is principally due to the intensifying breakdown of the...
the statepdflipidstoresreveal
https://www.ojp.gov/ncjrs/virtual-library/abstracts/characterizing-stutter-single-cells-and-impact-multi-cell-analysis
This article reports on the research methodology and outcomes from a project that characterized PCR artifacts (stutter) in single-cell samples to help generate...
single cellsthe impactstuttermulti
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.660350/full
Developmental hematopoiesis differs from adult and is far less described. In the developing embryo, waves of lineage-restricted blood precede the ultimate em...
blood systemfrontiersdefiningemergingdevelopment
https://www.mdpi.com/2305-6304/10/8/460
Subtle toxic effects may be masked in traditional assays that average or summate the response of thousands of cells. We overcome this by using the recent...
single celltoxicityorthodonticbracketsexamined
https://www.illumina.com/company/news-center/feature-articles/the-weizmann-institute-uses-novaseq-to-drive-single-cell-researc.html
Illumina and Israel-based Danyel Biotech today announced that scientists at the world-leading Weizmann Institute of Science in Israel are now using...
weizmann institutesingle cellusesdriveresearch
https://www.technologynetworks.com/proteomics/ebooks/advancing-single-cell-research-with-automation-394944
Learn how automated systems improve single-cell isolation, rare-cell analysis, and biologics discovery.
single cellstreamliningisolationautomationtechnology