https://pubmed.ncbi.nlm.nih.gov/28186131/
Multiple myeloma (MM) is a plasma cell cancer with poor survival, characterized by the expansion of multiple myeloma cells (MMCs) in the bone marrow. Using a...
replication stresshelicaseinvolvedsurvivaldrug
https://helicasemedia.com/portfolio
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helicasemediaportfolio
https://pubmed.ncbi.nlm.nih.gov/39792594/
Bloom syndrome helicase (Blm) is a RecQ family helicase involved in DNA repair, cell cycle progression, and development. Pathogenic variants in human BLM cause...
the bloomn terminalfunctionssyndromehelicase
https://link.springer.com/article/10.1038/emboj.2008.126?error=cookies_not_supported&code=9c6a289f-1199-4c85-8786-f11faaa3a2e1
Jun 26, 2008 - TANK‐binding kinase 1 (TBK1) is of central importance for the induction of type‐I interferon (IFN) in response to pathogens. We identified the
is ahelicasecriticalcomponent
https://www.ncbi.nlm.nih.gov/Structure/pdb/3LLM
ATP-DEPENDENT RNA HELICASE AAdenosine-5'-diphosphateCacodylate IonGlycerin; Propane-1,2,3-triolGlycerolManganese (ii) Ion
crystal structurerna helicaseanalysis
https://www.ncbi.nlm.nih.gov/Structure/cdd/cd12088
cd12088 (PSSM ID: 277187): Conserved Protein Domain Family helicase_insert_domain, helicase_insert_domain; This helical domain can be found inserted in a...
conserved proteincdddomainfamilyhelicase
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.1039440/full
Background: Recent studies have demonstrated the significance of the DEAD-box helicase 5 (DDX5) gene, which is involved in pathways concerning the modificati...
frontierspancanceranalysisprognostic
https://www.pearson.com/channels/gob/asset/3b6f65ef/how-many-helicase-enzymes-are-needed-for-a-strand-of-dna-that-possess-5-origins-
How many helicase enzymes are needed for a strand of DNA that possess 5 origins of replication?
how manyhelicaseenzymesneededstrand
https://pubmed.ncbi.nlm.nih.gov/9822692/
The rate of unwinding of duplex DNA by the herpes simplex virus type 1 (HSV-1)-encoded helicase-primase (primosome) was determined by measuring the rate of...
herpes simplex virustypehelicaseprimaseanalysis
https://www.mdpi.com/1422-0067/23/23/14678
A six-subunit ATPase ring forms the central hub of the replication forks in all domains of life. This ring performs a helicase function to separate the two...
mcm helicasetwodistinctmodesdna
https://pubmed.ncbi.nlm.nih.gov/37594235/
RNA helicases participate in nearly all aspects of RNA metabolism by rearranging RNAs or RNA-protein complexes in an adenosine triphosphate-dependent manner....
the deadrna helicaseboxrequired
https://www.rcsb.org/structure/7KRP
Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - BTC (local refinement)
sars covrcsbpdbstructurecomplex
https://elifesciences.org/articles/60371/figures
Ubiquitylation of the CMG helicase is inhibited throughout the initiation and elongation phases of chromosome replication by the DNA structure of a replication...
figuresdatacmghelicasedisassembly