https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.1066717/full
Frontiers | The enigmatic helicase DHX9 as a candidate prognostic biomarker for resected pancreatic...
Background Pancreatic ductal adenocarcinoma (PDAC) remains as one of the most lethal malignances and shows limited efficacy to current therapies. The DEAH-bo...
as a candidate
https://www.ncbi.nlm.nih.gov/gene/3345062
dnaB replicative DNA helicase [Corynebacterium glutamicum ATCC 13032] - Gene - NCBI
dnahelicasecorynebacteriumatccgene
https://experts.umn.edu/en/publications/features-of-double-stranded-rna-binding-domains-of-rna-helicase-a/
Features of double-stranded RNA-binding domains of RNA helicase A are necessary for selective...
https://pure.psu.edu/en/publications/real-time-observation-of-bacteriophage-t4-gp41-helicase-reveals-a/
Real-time observation of bacteriophage T4 gp41 helicase reveals an unwinding mechanism - Penn State
https://kuscholarworks.ku.edu/entities/publication/32129d1e-f63c-4c4c-a535-ecb200894751
Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase
The flavivirus nonstructural protein 3 (NS3) is a protease and helicase, and on the basis of its similarity to its homologue encoded by the hepatitis C virus...
flavivirusinhibitorstargetingviralhelicase
https://www.ncbi.nlm.nih.gov/protein/1IN8_A
Chain A, HOLLIDAY JUNCTION DNA HELICASE RUVB - Protein - NCBI
chainhollidayjunctiondnahelicase
https://www.ncbi.nlm.nih.gov/Structure/pdb/7AUD
7AUD: Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
Bloom syndrome protein,Bloom syndrome proteinDNA...
https://www.ncbi.nlm.nih.gov/protein/6L3G_A
Chain A, ATP-dependent DNA helicase - Protein - NCBI
chainatpdependentdnahelicase
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.633233/full
Frontiers | Role of Chromodomain-Helicase-DNA-Binding Protein 4 (CHD4) in Breast Cancer
Chromodomain-helicase-DNA-binding protein 4 (CHD4) is an epigenetic regulator identified as an oncogenic element that may provide a novel therapeutic target ...
https://www.wikidata.org/wiki/Q47315601
Kinetic measurement of the step size of DNA unwinding by Escherichia coli UvrD helicase - Wikidata
scientific article published in January 1997
https://scholars.lib.ntu.edu.tw/entities/publication/ddfe0fa7-e70c-46a1-ad17-4b4da44f0eb2
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
Mutations in the yeast Saccharomyces cerevisiae PIF1 gene, which encodes a 5'-to-3' DNA helicase, cause telomere lengthening and a large increase in the...
helicasecatalyticinhibitortelomeraseyeast
https://www.ncbi.nlm.nih.gov/nuccore/NM_032043
Homo sapiens BRCA1 interacting DNA helicase 1 (BRIP1), mRNA - Nucleotide - NCBI
homo sapiensinteractingdna
https://pubchem.ncbi.nlm.nih.gov/protein/A0A5F4CUS6
ATP-dependent DNA helicase 2 subunit 1 (dog) | Protein Target - PubChem
Protein target information for ATP-dependent DNA helicase 2 subunit 1 (dog). Find diseases associated with this biological target and compounds tested against...
atpdependentdnahelicase
https://eprints.soton.ac.uk/428938/
Correction to: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly...
https://pubchem.ncbi.nlm.nih.gov/protein/F1SDB8
Chromodomain helicase DNA binding protein 1 like (pig) | Protein Target - PubChem
Protein target information for Chromodomain helicase DNA binding protein 1 like (pig). Find diseases associated with this biological target and compounds...
helicasednabindingproteinlike
https://www.ncbi.nlm.nih.gov/gene/897204
ruvB Holliday junction branch migration DNA helicase RuvB [Thermotoga maritima MSB8] - Gene - NCBI
https://pubchem.ncbi.nlm.nih.gov/bioassay/504663
AID 504663 - Inhibitors of BLM Helicase: DNA Unwinding Measured by Gel Electrophoresis - RecQL1...
BioAssay record AID 504663 submitted by National Center for Advancing Translational Sciences (NCATS): Inhibitors of BLM Helicase: DNA Unwinding Measured by Gel...
https://www.wikidata.org/wiki/Q36588588
Identification of the gene for DNA helicase II of Escherichia coli - Wikidata
scientific article published on December 15, 1983
of theescherichia coliidentificationgene
https://research.manchester.ac.uk/en/publications/yeast-sen1-helicase-protects-the-genome-from-transcription-associ/
Yeast Sen1 helicase protects the genome from transcription-associated instability - Research...
the genomeyeasthelicaseprotects
https://eichler.gs.washington.edu/publication/de-novo-smarca2-variants-clustered-outside-the-helicase-domain-cause-a-new-recognizable-syndrome-with-intellectual-disability-and-blepharophimosis-distinct-from-nicolaides-baraitser-syndrome/
De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome...
Eichler Laboratory at the University of Washington Genome Sciences Department
https://scholars.duke.edu/publication/1582215
Scholars@Duke publication: The RNA helicase DDX39B activates FOXP3 RNA splicing to control T...
https://research-portal.st-andrews.ac.uk/en/publications/the-dna-helicase-chlr1-is-required-for-sister-chromatid-cohesion-/
The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells. - University...
https://pubchem.ncbi.nlm.nih.gov/protein/Q9HUN3
Replicative DNA helicase (Pseudomonas aeruginosa PAO1) | Protein Target - PubChem
Protein target information for Replicative DNA helicase (Pseudomonas aeruginosa PAO1). Find diseases associated with this biological target and compounds...
pseudomonas aeruginosadnahelicaseproteintarget
https://pubmed.ncbi.nlm.nih.gov/27107905/
Mutational analysis of FANCJ helicase
FANCJ is a superfamily 2 DNA helicase, which also belongs to the iron-sulfur domain containing helicases that include XPD, ChlR1 (DDX11), and RTEL1. Mutations...
analysishelicase
https://www.ncbi.nlm.nih.gov/gene/885442
uvrD1 ATP-dependent DNA helicase UvrD [Mycobacterium tuberculosis H37Rv] - Gene - NCBI
mycobacterium tuberculosisatpdependentdnahelicase
https://pubchem.ncbi.nlm.nih.gov/protein/F1NHI3
RNA helicase (chicken) | Protein Target - PubChem
Protein target information for RNA helicase (chicken). Find diseases associated with this biological target and compounds tested against it in bioassay...
rnahelicasechickenproteintarget
https://researchdiscovery.drexel.edu/esploro/outputs/doctoral/The-role-of-helicases-and-helicase-like/991014970229304721
The role of helicases and helicase-like proteins in homologous recombination - Drexel University
Homologous recombination is important for repair of the most harmful types of DNA damage including DNA double-strand breaks, interstrand cross-links, and for...
https://pubchem.ncbi.nlm.nih.gov/protein/A0A8I3Q9W9
RNA helicase (dog) | Protein Target - PubChem
Protein target information for RNA helicase (dog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
rnahelicasedogproteintarget
https://www.ncbi.nlm.nih.gov/protein/5RM8_A
Chain A, Helicase - Protein - NCBI
chainhelicaseproteinncbi
https://experts.colorado.edu/display/pubid_112304
A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal...
https://www.ncbi.nlm.nih.gov/Structure/pdb/8RIG
8RIG: Cryo-EM structure of an MCM helicase single hexamer loaded onto dsDNA
DNA (5'-D(P*AP*TP*GP*CP*AP*TP*GP*CP*AP*TP*GP*CP*AP*TP*GP*CP*AP*T)-3')DNA (5'-D(P*GP*CP*AP*TP*GP*CP*AP*TP*GP*CP*AP*TP*GP*CP*AP*TP*GP*CP*AP*T)-3')DNA replication...
https://pediatrics.ucsf.edu/node/301681
CHAMP, a novel cardiac-specific helicase regulated by MEF2C. | Department of Pediatrics
a novel
https://pubmed.ncbi.nlm.nih.gov/28729513/
Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading
Bidirectional replication from eukaryotic DNA replication origins requires the loading of two ring-shaped minichromosome maintenance (MCM) helicases around DNA...
dna replicationbidirectional
https://pubchem.ncbi.nlm.nih.gov/protein/A0A8I3NC92
RNA helicase (dog) | Protein Target - PubChem
Protein target information for RNA helicase (dog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
rnahelicasedogproteintarget
https://pubchem.ncbi.nlm.nih.gov/protein/A2ACQ1
RNA helicase (house mouse) | Protein Target - PubChem
Protein target information for RNA helicase (house mouse). Find diseases associated with this biological target and compounds tested against it in bioassay...
house mousernahelicaseproteintarget
https://www.wikidata.org/wiki/Q35116428
Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active...
scientific article published in July 2000
https://pubmed.ncbi.nlm.nih.gov/35283818/?dopt=Abstract
Contribution of DEAD-Box RNA Helicase 21 to the Nucleolar Localization of Porcine Circovirus Type 4...
Porcine circovirus type 4 (PCV4) is a newly emerging pathogen which might be associated with diverse clinical signs, including respiratory and gastrointestinal...
https://edrn.cancer.gov/data-and-resources/publications/23908689-altered-recq-helicase-expression-in-sporadic-primary-colorectal-cancers/
Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.
This is a publication by a member of the Early Detection Research Network.
alteredhelicaseexpressionprimarycolorectal
https://pubchem.ncbi.nlm.nih.gov/protein/A0A8I3PAP2
RNA helicase (dog) | Protein Target - PubChem
Protein target information for RNA helicase (dog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
rnahelicasedogproteintarget
https://pmc.ncbi.nlm.nih.gov/articles/PMC29721/
Characterization and mutational analysis of yeast Dbp8p, a putative RNA helicase involved in...
RNA helicases of the DEAD box family are involved in almost all cellular processes involving RNA molecules. Here we describe functional characterization of the...
https://scholars.lib.ntu.edu.tw/entities/project/a3af1bd3-069a-46ee-9749-5332630d4a8a
Expression of Putative RNA Helicase Gene of HCV and Assay for Its Enzymatic Activity
https://boris-portal.unibe.ch/entities/publication/dd4b2b0d-7992-4989-8c8b-d1724fe85cc2
Selective pharmacological targeting of a DEAD box RNA helicase
RNA helicases represent a large family of proteins implicated in many biological processes including ribosome biogenesis, splicing, translation and mRNA...
of aselectivepharmacologicaltargetingdead
https://shop.elsevier.com/books/helicase-enzymes-part-a/trakselis/978-0-323-91476-5
Helicase Enzymes Part A, Volume 672 - 1st Edition | Elsevier Shop
part ahelicaseenzymesvolumeedition
https://dukespace.lib.duke.edu/items/d3e8521c-62b8-4045-b4e9-7648288bc196/full
Chromatin Dynamics and Regulation of the Helicase During Replication Initiation
of thechromatindynamicsregulationhelicase
https://experts.colorado.edu/display/pubid_59414
The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding...
https://www.helicasemedia.com/
Helicase Media
Professional video production and video hosting company based in Los Angeles, CA
helicasemedia
https://www.ncbi.nlm.nih.gov/Structure/pdb/5RL6
5RL6: PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 helicase in complex with...
HelicasePHOSPHATE IONZINC ION
https://pubchem.ncbi.nlm.nih.gov/protein/H0YU56
DNA helicase (zebra finch) | Protein Target - PubChem
Protein target information for DNA helicase (zebra finch). Find diseases associated with this biological target and compounds tested against it in bioassay...
zebra finchdnahelicaseproteintarget
https://www.ncbi.nlm.nih.gov/protein/3O8R_B
Chain B, HCV NS3 protease/helicase - Protein - NCBI
chainbhcvproteasehelicase
https://pubmed.ncbi.nlm.nih.gov/9565667/?dopt=Abstract
A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to humans
We have identified a novel Drosophila protein, DBP80, that exhibits significant similarity to mouse mDEAD5, yeast TIF1/2, and mammalian eIF-4A. DBP80 is a...
https://pure.psu.edu/en/publications/yeast-hrq1-shares-structural-and-functional-homology-with-the-dis/
Yeast Hrq1 shares structural and functional homology with the disease-linked human RecQ4 helicase -...
https://pubmed.ncbi.nlm.nih.gov/35815807/
The X-Linked Helicase DDX3X Is Required for Lymphoid Differentiation and MYC-Driven Lymphomagenesis
The sex-dependent effects of DDX3X deficiency in malignant transformation of B cells and the compensatory role of DDX3Y support inhibition of DDX3 as a...
https://pubchem.ncbi.nlm.nih.gov/protein/Q6AUI3
General transcription and DNA repair factor IIH helicase subunit XPD (Japanese rice) | Protein...
Protein target information for General transcription and DNA repair factor IIH helicase subunit XPD (Japanese rice). Find diseases associated with this...
https://pubchem.ncbi.nlm.nih.gov/protein/M3TYJ4
DNA helicase (pig) | Protein Target - PubChem
Protein target information for DNA helicase (pig). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
dnahelicasepigproteintarget
https://pmc.ncbi.nlm.nih.gov/articles/PMC18546/
UvrA and UvrB suppress illegitimate recombination: Synergistic action with RecQ helicase - PMC
Illegitimate recombination is a major cause of genetic instability in prokaryotes as well as in eukaryotes. This recombination usually occurs at a low...
https://www.wikidata.org/wiki/Q37041285
A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and...
scientific article published on December 1996
https://microbiology.weill.cornell.edu/binding-and-melting-d-loops-bloom-syndrome-helicase
Binding and melting of D-loops by the Bloom syndrome helicase. | Microbiology and Immunology
https://www.ncbi.nlm.nih.gov/Structure/pdb/5RMH
5RMH: PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 helicase in complex with...
HelicasePHOSPHATE IONZINC ION[(4S)-4-methylazepan-1-yl](1,3-thiazol-4-yl)methanone
https://www.ncbi.nlm.nih.gov/gene/1653
DDX1 DEAD-box helicase 1 [Homo sapiens (human)] - Gene - NCBI
homo sapienshuman genedeadboxhelicase
https://midwestavidd.umn.edu/research/project-5-pandemic-virus-helicase-inhibitors
Project 5: Pandemic Virus Helicase Inhibitors | Midwest Antiviral Drug Discovery (AViDD) Center
https://pubmed.ncbi.nlm.nih.gov/18479669/
Viral NS3 helicase activity is inhibited by peptides reproducing the Arg-rich conserved motif of...
The NTPase/helicase of Flaviviridae viruses is one of the essential components of their replication complex. The enzyme is defined by the presence of seven...
https://experts.colorado.edu/display/pubid_31736
Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase | CU Experts | CU...
https://experts.arizona.edu/en/publications/rnf4-regulates-the-blm-helicase-in-recovery-from-replication-fork/
RNF4 Regulates the BLM Helicase in Recovery From Replication Fork Collapse - University of Arizona
https://pure.psu.edu/en/publications/structural-and-biological-identification-of-residues-on-the-surfa/
Structural and biological identification of residues on the surface of NS3 helicase required for...
on the surface
https://www.ncbi.nlm.nih.gov/protein/62391827?report=GenPept
Record removed: replicative DNA helicase [Corynebacterium glutamicum ATCC 13032] - Protein - NCBI
recordremoveddnahelicase
https://pure.psu.edu/en/publications/ns3-helicase-from-the-hepatitis-c-virus-can-function-as-a-monomer/
NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme...
https://scholarsarchive.byu.edu/jur/vol2013/iss1/1279/
"Twinkle Primase/Helicase Protein in Arabidopsis thaliana" by Travis Hunt and Dr. Brent Nielsen
The overall goal of the project was to study the role of DNA recombination in maintenance of plant mitochondrial DNA (mtDNA). Recombination is the process by...
https://www.sciencedaily.com/releases/2015/09/150910111554.htm
Modeling the helicase to understand hepatitis C | ScienceDaily
NS3 is an enzyme specific to the hepatitis C virus. If developed, a drug capable of recognizing and selectively attacking it could fight the disease without...
to understandhepatitis cmodelinghelicasesciencedaily
https://www.ncbi.nlm.nih.gov/protein/196155391?report=GenPept
Record removed: ATP-dependent RNA helicase RhlB [Alteromonas macleodii 'Deep ecotype'] - Protein -...
https://www.wikidata.org/wiki/Q70134303
The Escherichia coli dnaB replication protein is a DNA helicase - Wikidata
scientific article published on 01 April 1986
escherichia colireplication
https://www.wikidata.org/wiki/Q28250576
RNA Helicase A Mediates Association of CBP with RNA Polymerase II - Wikidata
scientific article (publication date: 19 September 1997)
rnahelicaseassociation
https://www.research.ed.ac.uk/en/publications/genetic-evidence-of-the-association-of-deah-box-helicase-37-defec/
Genetic evidence of the association of DEAH-box helicase 37 defects with 46,XY gonadal dysgenesis...
https://www.ncbi.nlm.nih.gov/protein/3O8R_A
Chain A, HCV NS3 protease/helicase - Protein - NCBI
chainhcvproteasehelicaseprotein
https://www.ncbi.nlm.nih.gov/Structure/pdb/5TXG
5TXG: Crystal structure of the Zika virus NS3 helicase
NS3 helicase2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLPOTASSIUM ION
crystal structureof thezika virushelicase
https://pmc.ncbi.nlm.nih.gov/articles/PMC50965/
Association of DNA helicase and primase activities with a subassembly of the herpes simplex virus 1...
Herpes simplex virus 1 encodes a helicase-primase that is composed of the products of the UL5, UL8, and UL52 genes. A stable subassembly consisting of only the...
https://www.helicase.net/
DExH/D protein family db Helicase Enzymes – E. coli recombinant human Protein for normal cell...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010853
Identification of the nuclear localization signal in the Saccharomyces cerevisiae Pif1 DNA helicase...
Author summary Investigation of proteins involved in maintaining genomic stability is important for understanding how genetic diseases, such as cancer, arise....
of thesignal in
https://vivo.colorado.edu/display/pubid_12913
Herpes Simplex Virus Type 1 Helicase-Primase: DNA Binding and Consequent Protein Oligomerization...
herpes simplex virus
https://scholarworks.gsu.edu/items/47084838-0f81-4b46-8cb0-e38247e15f8e
The RNA Helicase p68 Regulates Transcription by Facilitating Chromatin Remodeling
rnahelicasetranscriptionfacilitatingchromatin
https://pubmed.ncbi.nlm.nih.gov/32984035/
Genomic Profiling Identified ERCC2 E606Q Mutation in Helicase Domain Respond to Platinum-Based...
Genomic profiling of tumors enables therapeutic decisions, and identifying drug-matched mutations will prolong survival and prognosis. Here, we generated a...
https://pubchem.ncbi.nlm.nih.gov/bioassay/720489
AID 720489 - Fluorescence-based confirmation counterscreen assay for HCV NS3 helicase inhibitors of...
BioAssay record AID 720489 submitted by Milwaukee Institute for Drug Discovery: Fluorescence-based confirmation counterscreen assay for HCV NS3 helicase...
https://researchfestival.nih.gov/2024/posters/new-kinetic-assay-monitors-helicase-unwinding-g-quadruplexes
A new kinetic assay that monitors helicase unwinding of G-quadruplexes | NIH Research Festival
https://www.ncbi.nlm.nih.gov/protein/914734392?report=GenPept
ATP-dependent helicase HrpB [Schaalia meyeri] - Protein - NCBI
atpdependenthelicaseproteinncbi
https://scholarworks.gsu.edu/items/fb4a3d7b-f67f-418d-8d08-f2222685dbc0
A Novel Function of DEAD Box p68 RNA Helicase In Tumor Cell Proliferation And...
https://www.ncbi.nlm.nih.gov/protein/8PO7_B
Chain B, ATP-dependent RNA helicase HrpA - Protein - NCBI
chainbatpdependentrna
https://pubchem.ncbi.nlm.nih.gov/protein/P03692
DNA helicase/primase (Escherichia phage T7) | Protein Target - PubChem
Protein target information for DNA helicase/primase (Escherichia phage T7). Find diseases associated with this biological target and compounds tested against...
dnahelicaseescherichiaphageprotein
https://pmc.ncbi.nlm.nih.gov/articles/PMC3830938/
Molecular crowding enhanced ATPase activity of the RNA helicase eIF4A correlates with compaction of...
Enzymatic reactions occur in a crowded and confined environment in vivo, containing proteins, RNA and DNA. Previous reports have shown that interactions...
https://pubmed.ncbi.nlm.nih.gov/30797687/
Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA
In cells, dedicated AAA+ ATPases deposit hexameric, ring-shaped helicases onto DNA to initiate chromosomal replication. To better understand the mechanisms by...
for theof a
https://pmc.ncbi.nlm.nih.gov/articles/PMC15095/
Mechanism of recruitment of DnaB helicase to the replication origin of the plasmid pSC101 - PMC
Although many bacterial chromosomes require only one replication initiator protein, e.g., DnaA, most plasmid replicons depend on dual initiators: host-encoded...
to the
https://pubmed.ncbi.nlm.nih.gov/10749921/
A novel helicase-type protein in the nucleolus: protein NOH61
We report the identification, cDNA cloning, and molecular characterization of a novel, constitutive nucleolar protein. The cDNA-deduced amino acid sequence of...
a novelin thehelicasetypeprotein