Robuta

https://pmc.ncbi.nlm.nih.gov/articles/PMC7021003/ Regenerative lineages and immune-mediated pruning in lung cancer metastasis - PMC Developmental processes underlying normal tissue regeneration have been implicated in cancer, but the degree of their enactment during tumor progression and... immune mediatedlung cancerregenerativelineages https://pmc.ncbi.nlm.nih.gov/articles/PMC8727136/ Hypoplastic myelodysplastic syndrome and acquired aplastic anemia: Immune-mediated bone marrow... Hypoplastic myelodysplastic syndrome (hMDS) and aplastic anemia (AA) are rare hematopoietic disorders characterized by pancytopenia with hypoplastic bone... acquired aplastic anemiamyelodysplastic syndromeimmune mediatedhypoplastic https://www.quell-tx.com/ Transforming lives in immune-mediated disease - Quell Therapeutics Quell Therapeutics is a clinical-stage company, fuelled by curiosity and discovery, on a mission to make life better for those battling severe immune and... immune mediated diseasetransforming livesquelltherapeutics https://pmc.ncbi.nlm.nih.gov/articles/PMC40209/ Development and characterization of a rodent model of immune-mediated cholangitis - PMC The cholangiopathies are a group of hepatobiliary diseases in which intrahepatic bile duct epithelial cells, or cholangiocytes, are the target for a variety of... rodent modelimmune mediateddevelopmentcharacterization https://www.gla.ac.uk/research/az/imid/ University of Glasgow - Research - Research units A-Z - Immune-Mediated Inflammatory Disease... university of glasgowresearch unitsimmune mediated https://www.biospace.com/business/nasdaq-neophytes-acelyrin-alumis-merge-to-tackle-immune-mediated-diseases Nasdaq Neophytes Acelyrin, Alumis Merge to Tackle Immune-Mediated Diseases - BioSpace Feb 7, 2025 - Alumis held its initial public offering in June last year, while Acelyrin debuted on the Nasdaq in mid-2023. immune mediatednasdaqneophytesacelyrinmerge https://pmc.ncbi.nlm.nih.gov/articles/PMC9959504/ Tyk2 Targeting in Immune-Mediated Inflammatory Diseases - PMC The Janus kinase (Jak)/signal transducer and activating protein (STAT) pathways mediate the intracellular signaling of cytokines in a wide spectrum of cellular... immune mediatedinflammatory diseasestyk2targetingpmc https://www.tempesttx.com/ Tempest Therapeutics | Targeted and Immune-Mediated Cancer Therapies Tempest Therapeutics is developing first-in-class small molecule product candidates with broad potential benefit to patients. immune mediatedtempesttherapeuticstargetedcancer https://www.mdpi.com/books/reprint/8162-omics-approaches-to-immune-mediated-inflammatory-diseases-towards-novel-biomarkers-and-potential Omics Approaches to Immune-Mediated Inflammatory Diseases: Towards Novel Biomarkers and Potential... Chronic immune-mediated inflammatory diseases (IMIDs), usually accompanied by cardiovascular disease and neoplasias, are now prevailed worldwide. The limited... immune mediatedinflammatory diseases https://www.frontiersin.org/research-topics/30565/immune-mediated-lung-injury/magazine Immune-Mediated Lung Injury | Frontiers Research Topic A possible association between interstitial lung diseases and autoimmunity was first reported almost 40 years ago. Despite further reports linking immune... immune mediatedlunginjuryfrontiersresearch https://www.gla.ac.uk/research/az/imid/contact/ University of Glasgow - Research - Research units A-Z - Immune-Mediated Inflammatory Disease... university of glasgowresearch unitsimmune mediated https://www.fraunhofer.de/en/institutes/institutes-and-research-establishments-in-germany/cluster-of-excellence/immune-mediated-diseases.html Immune-Mediated Diseases immune mediateddiseases https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1537314/full Frontiers | Editorial: Regulatory T cells in immune-mediated diseases During the 1970s and 1980s, research in murine models suggested the existence of CD8 + I-J + T cells as suppressor cells. However, the inability to locate th... regulatory t cellsimmune mediatedfrontierseditorialdiseases https://www.fda.gov/regulatory-information/search-fda-guidance-documents/characterizing-collecting-and-reporting-immune-mediated-adverse-reactions-cancer-immunotherapeutic Characterizing, Collecting, and Reporting Immune-Mediated Adverse Reactions in Cancer... This guidance is intended for sponsors of cancer immunotherapeutic drugs that modulate the endogenous immune system and may break immunologic tolerance to... immune mediatedadverse reactionscollectingreportingcancer https://www.healthday.com/healthpro-news/cancer/cancer-risk-elevated-in-patients-with-immune-mediated-inflammatory-disease Cancer Risk Elevated With Immune-Mediated Inflammatory Disease Patients with immune-mediated inflammatory disease have an increased cancer risk, especially in the first year after diagnosis. cancer riskimmune mediatedelevatedinflammatorydisease https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1273062/full Frontiers | Editorial: Rare immune-mediated diseases- novel insights into underlying mechanisms and... Rare Immune-mediated Diseases-Novel Insights into Underlying Mechanisms and TherapeuticOur understanding of the underlying mechanisms of the immune system ha... immune mediated https://www.aldeyra.com/ Medicines to Treat Immune-Mediated Diseases | Aldeyra Therapeutics, Inc. Oct 28, 2025 - Learn more about Aldeyra Therapeutics, devoted to inventing, developing, and commercializing next-generation medicines that treat immune-mediated disease. immune mediatedmedicinestreatdiseasestherapeutics https://uwaterloo.ca/applied-mathematics/events/applied-math-seminar-thomas-hillen-mathematical-modeling Applied Math Seminar | Thomas Hillen, Mathematical Modeling of the Immune-Mediated Theory of... Accumulating experimental and clinical evidence suggests that the immune response to cancer is not exclusively anti-tumor. applied math seminarmathematical modeling https://www.proquest.com/docview/305323217 Host inflammatory response and vaccine -mediated immune protection against Mycoplasma gallisepticum... Explore millions of resources from scholarly journals, books, newspapers, videos and more, on the ProQuest Platform. inflammatory responsehostvaccine https://www.erowid.org/references/refs_view.php?ID=1423&S=Roset_P&SField=all Erowid.org: Erowid Reference 1423 : Cell-mediated immune response in MDMA users after repeated dose... The Index page for the reference article: Pacifici R, Zuccaro P, Farre M, Pichini S, Di Carlo S, Roset PN, Palmi I, Ortuno J, Menoyo E, Segura J, de la Torre R... cell mediated immune response https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1512981/full Frontiers | SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer BackgroundSqualene epoxidase (SQLE) is a key enzyme in cholesterol biosynthesis and has been shown to negatively affect tumor immunity and is associated with... https://www.ouromedicines.com/ Defining the future of treatment for people with immune-mediated diseases | Ouro Medicines Ouro Medicines is a biotechnology company developing immune reset therapeutics for people living with chronic immune-mediated diseases. the future of https://www.mdpi.com/journal/ijms/special_issues/Interleukins_Allergic IJMS | Special Issue : Interleukins in Allergic and Immune-Mediated Diseases: A Cascade of Multiple... International Journal of Molecular Sciences, an international, peer-reviewed Open Access journal. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2019.01206/full Frontiers | The Reversal of Immune Exclusion Mediated by Tadalafil and an Anti-tumor Vaccine Also... Myeloid Derived suppressor cells (MDSCs) play a key role in the progression and recurrence of human malignancies and in restraining the efficacy of adjuvant ... https://www.erowid.org/references/refs_view.php?ID=1423&S=De_La_Torre_R&SField=all Erowid.org: Erowid Reference 1423 : Cell-mediated immune response in MDMA users after repeated dose... The Index page for the reference article: Pacifici R, Zuccaro P, Farre M, Pichini S, Di Carlo S, Roset PN, Palmi I, Ortuno J, Menoyo E, Segura J, de la Torre R... cell mediated immune response https://www.frontiersin.org/research-topics/18925/towards-precision-medicine-for-immune-mediated-disorders-advances-in-using-big-data-and-artificial-intelligence-to-understand-heterogeneity-in-inflammatory-responses/magazine Towards Precision Medicine for Immune-Mediated Disorders: Advances in Using Big Data and Artificial... https://elifesciences.org/articles/66222/peer-reviews Peer review in A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to... A genome-wide in vivo CRISPR screen identifies an IL-20/IL20RA-mediated crosstalk between peritoneum mesothelial cells and ovarian cancer cells that promotes... https://www.mdpi.com/2076-393X/7/4/125 Immune Modulation and Immune-Mediated Pathogenesis of Emerging Tickborne Banyangviruses In the last decade, the emergence of several, novel tickborne viruses have caused significant disease in humans. Of interest are the tickborne banyangviruses:... immune modulationmediatedpathogenesisemerging https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2014.00586/full Frontiers | Salmonella Modulates B Cell Biology to Evade CD8+ T Cell-Mediated Immune Responses Although B cells and antibodies are the central effectors of humoral immunity, B cells can also produce and secrete cytokines and present antigen to helper T... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.643615/full Frontiers | A Diagnostic Panel for Acquired Immune-Mediated Polyneuropathies Based on the... Long non-coding RNAs (lncRNAs) have been shown to alter immune responses, thus contributing in the pathobiology of autoimmune conditions. We investigated the... https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2020.606322/full Frontiers | miRNA-Mediated Immune Regulation in Islet Autoimmunity and Type 1 Diabetes microRNAs have emerged as critical modulators of immune regulation and homeostasis. Their dysregulation is involved in the aberrant differentiation and funct... https://www.preprints.org/manuscript/202112.0290/v2 Epigenetic Modulation of Gremlin-1/NOTCH Pathway in Experimental Crescentic Immune-Mediated... Crescentic glomerulonephritis is a devastating autoimmune disease that without early and properly treat-ment may rapidly progress to end-stage renal disease... notch pathway https://www.mdpi.com/2077-0383/11/9/2455 Fatigue and Associated Factors in an Immune-Mediated Inflammatory Disease Population: A... Fatigue is a main symptom of chronic diseases, including immune-mediated inflammatory diseases (IMIDs), such as inflammatory bowel disease (IBD) and... in an https://www.jci.org/articles/view/129497 JCI - HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING immune escape https://finviz.com/news/340734/royalty-pharma-announces-rd-funding-collaboration-for-chronic-immune-mediated-diseases Royalty Pharma Announces R&D Funding Collaboration for Chronic Immune-Mediated Diseases Stock screener for investors and traders, financial visualizations. royalty pharma https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.920164/full Frontiers | m5C Regulator-mediated methylation modification clusters contribute to the immune... AbstractBackground: Multiple myeloma (MM) is a hematological malignancy in which plasma cells proliferate abnormally. 5-methylcytosine (m5C) methylation modi... to thefrontiersm5cregulatormediated https://investingnews.com/royalty-pharma-announces-rd-funding-collaboration-for-chronic-immune-mediated-diseases/ Royalty Pharma Announces R&D Funding Collaboration for Chronic Immune-Mediated Diseases | INN https://www.frontiersin.org/journals/ecology-and-evolution/articles/10.3389/fevo.2021.629094/full Frontiers | Cell-Mediated Immune Ontogeny Is Affected by Sex but Not Environmental Context in a... Ecoimmunology conceptualizes the role of immunity in shaping life history in a natural context. Within ecoimmunology, macroimmunology is a framework that exp... https://pmc.ncbi.nlm.nih.gov/articles/PMC4666791/ The Type I Interferons: Basic Concepts and Clinical Relevance in Immune-mediated Inflammatory... There is increasing scientific and clinical interest in elucidating the biology of type I Interferons, which began approximately 60 years ago with the concept... https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1250918/full Frontiers | Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3... Ischemic stroke (IS) is a major cause of mortality and disability among adults.Recanalization of blood vessels to facilitate timely reperfusion is the primar... in researchon the https://www.uni-muenster.de/Biologie.IBBP/agmoerschbacher/news/2025/htdabioactivity.html Paper accepted: Chitosan production methods influence receptor-mediated immune responses but not... AG Moerschbacher - News production methods https://elifesciences.org/reviewed-preprints/95952v1/figures Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape nonsense mediated decay https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1501908/full Frontiers | Humoral and cell-mediated immune responses to COVID-19 vaccines up to 6 months post... PurposeMany individuals with inborn errors of immunity (IEIs) have poor humoral immune (HI) vaccine responses. Only a few studies have examined specific cell... https://www.frontiersin.org/news/2024/04/04/scientists-call-for-urgent-action-to-prevent-immune-mediated-illnesses Scientists call for urgent action to prevent immune-mediated illnesses caused by climate change and... Climate change, pollution, and collapsing biodiversity are damaging our immune systems, but improving the environment offers effective and fast-acting protectio https://www.mdpi.com/1999-4915/16/4/574 STINGing Defenses: Unmasking the Mechanisms of DNA Oncovirus-Mediated Immune Escape DNA oncoviruses represent an intriguing subject due to their involvement in oncogenesis. These viruses have evolved mechanisms to manipulate the host immune... stingingdefensesunmaskingmechanisms https://pmc.ncbi.nlm.nih.gov/articles/PMC11421408/ Real-World Experience With Janus Kinase Inhibitors in Immune-Mediated Diseases: Clinical Experience... Background: Several Janus kinase (JAK) inhibitors have been developed in recent years. These agents are widely applicable in clinical practice as an... real world experiencejanus kinase https://www.jci.org/articles/view/195137/pdf JCI - Myeloid-mediated cerebral amyloid vasculitis and the potential role of the immune response in... https://www.frontiersin.org/research-topics/55533/immune-mediated-damage-to-the-heart-and-lungs-in-autoimmune-diseases/magazine Immune-Mediated Damage to the Heart and Lungs in Autoimmune Diseases | Frontiers Research Topic Autoimmune diseases are a group of disorders in which the immune system mistakenly attacks healthy tissues and organs, leading to inflammation and damage.... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1301109/full Frontiers | Anti-SRP immune-mediated necrotizing myopathy responsive to ofatumumab: a case report Background: Immune-mediated necrotizing myopathies (IMNM) is a rare disease that was first described in 2004. Due to the lack of large case series, there are... https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2019.00119/full Frontiers | Biomarkers for Immune Checkpoint Inhibitor-Mediated Tumor Response and Adverse Events In the last decade, inhibitors targeting immune checkpoint molecules such as cytotoxic T-lymphocyte antigen 4 (CTLA-4), programmed cell death 1 (PD-1) and pr... immune checkpoint inhibitor https://www.mdpi.com/1999-4915/11/8/681 Current Findings on Gut Microbiota Mediated Immune Modulation against Viral Diseases in Chicken Chicken gastrointestinal tract is an important site of immune cell development that not only regulates gut microbiota but also maintains extra-intestinal... https://www.wikidata.org/wiki/Q36358820 Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of... scientific article published on December 1, 1975 https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.632934/full Frontiers | RNA N6-Methyladenosine Regulator-Mediated Methylation Modifications Pattern and Immune... Glioblastoma (GBM) is a group of intracranial neoplasms with intra-tumoral heterogeneity. RNA N6-methyladenosine (m6A) methylation modification reportedly pl... n6 methyladenosinefrontiersrnaregulator https://elifesciences.org/articles/66222/figures Figures and data in A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to... A genome-wide in vivo CRISPR screen identifies an IL-20/IL20RA-mediated crosstalk between peritoneum mesothelial cells and ovarian cancer cells that promotes... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.651049/full Frontiers | IgA Immune Complexes Induce Osteoclast-Mediated Bone Resorption Objective: Autoantibodies are detected in most patients with rheumatoid arthritis (RA) and can be of the IgM, IgG or IgA subclass. Correlations between IgA a... immune complexesfrontiersigainduceosteoclast https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.770275/full Frontiers | Editorial: Role of the IL-23/IL-17 Pathway in Chronic Immune-Mediated Inflammatory... These findings demonstrate our limited understanding of the pathogenic mechanisms of IL-17 and IL-23 in these CIDs, suggesting the need to reassess the link ...