Robuta

https://scholars.lib.ntu.edu.tw/entities/project/c51e7a86-c775-4b8a-87b7-f063cdcf38f4 Exploration of the Regulation of Mtor Inhibitors on the Functions of Antigen Presenting Cells and... antigen presenting cellsof themtor inhibitors https://pubmed.ncbi.nlm.nih.gov/26927950/ The Role of mTOR Inhibitors in the Treatment of Patients with Tuberous Sclerosis Complex:... Tuberous sclerosis complex (TSC) is a genetic disorder arising from mutations in the TSC1 or TSC2 genes. The resulting over-activation of the mammalian target... the rolemtor inhibitors https://pubmed.ncbi.nlm.nih.gov/36274448/ Anal Cancer Prevention Through the Topical Use of Single or Dual PI3K/mTOR Inhibitors Sapanisertib, the mTOR inhibitor, had the greatest effect, in terms of increasing tumor-free survival, regardless of starting time point or sex. Unlike the... https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1007264 Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated... Author summary Dysregulated mRNA translation occurs frequently in tumours due to elevated eIF4E expression or a hyperactive mTOR complex 1 (mTORC1) signaling... https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2019.00236/full Frontiers | Novel 4-Acrylamido-Quinoline Derivatives as Potent PI3K/mTOR Dual Inhibitors: The... A novel structural series of quinoline derivatives were designed, synthesized and biologically evaluated as PI3K/mTOR dual inhibitors upon incorporation of C...