Robuta

https://www.phenogenomics.cz/phenotyping/cardiovascular/ Cardiovascular - Czech Centre for Phenogenomics Beyond routine cardiovascular assessment, the Unit integrates imaging and physiological monitoring into broader preclinical phenotyping pipelines. czech centrecardiovascularphenogenomics https://www.phenogenomics.cz/rare-diseases/gene-nomination/ Gene Nomination - Czech Centre for Phenogenomics SUBMIT NOMINATION ENG ODESLAT NOMINACI CZ The Czech Centre for Phenogenomics (CCP) is excited to announce the 3rd Call for Nomination of Genes or Diseases… czech centregenenominationphenogenomics https://www.phenogenomics.cz/rare-diseases/liang-wang-syndrome/ Liang-Wang Syndrome - Czech Centre for Phenogenomics Pathogenic mechanisms Liang-Wang syndrome is caused by mutations in the KCNMA1 gene, which affect various regions, including the transmembrane domains… czech centreliangwangsyndromephenogenomics https://www.phenogenomics.cz/phenotyping/metabolism/ Metabolism - Czech Centre for Phenogenomics The platform combines functional and behavioral measurements to provide a comprehensive view of metabolic regulation. Glucose and insulin tolerance tests... czech centremetabolismphenogenomics https://www.phenogenomics.cz/request-for-services/ Request for services - Czech Centre for Phenogenomics Please, print it, sign it (or insert an electronic signature), and send it to the e-mail: ccp-customer-service@img.cas.cz If you do not receive your account… services czechrequestcentrephenogenomics https://www.phenogenomics.cz/about-us/jobs/ Careers - Czech Centre for Phenogenomics Research and science jobs available in the CCP. Job offers, research jobs, science, career, HR, work, laboratory technician, researcher, scientist, biology,... czech centrecareersphenogenomics https://www.phenogenomics.cz/2026/01/from-vision-to-excellence/ From Vision to Excellence - Czech Centre for Phenogenomics Jan 15, 2026 - This year, the Czech Centre for Phenogenomics celebrates ten years as a national and European hub for advanced disease modelling and phenotyping. czech centrevisionexcellencephenogenomics https://www.phenogenomics.cz/rare-diseases/prader-willi-syndrome/ Prader-Willi Syndrome - Czech Centre for Phenogenomics Pathogenic mechanisms Prader-Willi Syndrome (PWS) results from the absence of paternal genetic material on chromosome 7. This absence leads to the loss of… prader willi syndromeczech centrephenogenomics https://www.phenogenomics.cz/2026/01/a-decade-of-high-impact-science/ A Decade of High-Impact Science - Czech Centre for Phenogenomics Jan 14, 2026 - The Czech Centre for Phenogenomics is renowned for its service to the user community, its scientific footprint is perhaps best measured by the calibre of… high impactczech centredecadesciencephenogenomics https://www.phenogenomics.cz/category/news/information/ Category: Information - Czech Centre for Phenogenomics czech centrecategoryinformationphenogenomics https://www.phenogenomics.cz/preclinical-testing/ Preclinical Testing - Czech Centre for Phenogenomics We can prepare and proceed projects from a broad variety of physiological categories from single parameter analysis (for example glucose level) to multi… czech centrepreclinicaltestingphenogenomics https://www.phenogenomics.cz/phenotyping/interactive-presentations-of-phenotyping-data/ Interactive Presentations of Phenotyping Data - Czech Centre for Phenogenomics czech centreinteractivepresentationsphenotypingdata https://www.phenogenomics.cz/phenotyping/metabolomics/ Metabolomics - Czech Centre for Phenogenomics The Unit enables detailed characterization of metabolic pathways and their perturbations across biological systems, including blood, tissues… czech centremetabolomicsphenogenomics https://www.phenogenomics.cz/rare-diseases/rare-disease-factory/ Rare Disease Factory - Czech Centre for Phenogenomics The Czech Centre for Phenogenomics, in collaboration with the Institute of Molecular and Translational Medicine is excited to announce the RD-Factory Program. rare diseaseczech centrefactoryphenogenomics https://www.phenogenomics.cz/2026/02/rare-disease-day-2026-rare-close-to-science/ Rare Disease Day 2026: Rare Close to Science - Czech Centre for Phenogenomics Mar 2, 2026 - On the occasion of Rare Disease Day 2026, we invited professionals and the general public to two exceptional events connecting science, patients, and research… rare disease dayczech centreclosesciencephenogenomics https://www.phenogenomics.cz/rare-diseases/achondroplasia/ Achondroplasia - Czech Centre for Phenogenomics Pathogenic mechanism Achondroplasia is caused by a gain of function autosomal dominant mutations in the FGFR3 receptor tyrosine kinase, a negative regulator of… czech centrephenogenomics https://www.phenogenomics.cz/rare-diseases/angelman-syndrome/ Angelman Syndrome - Czech Centre for Phenogenomics Pathogenic mechanisms The Ube3a gene has been identified as the causative gene of Angelman syndrome. It is paternally imprinted (i.e. silenced) in mature… angelman syndromeczech centrephenogenomics https://www.phenogenomics.cz/about-us/ About Us - Czech Centre for Phenogenomics us czechcentrephenogenomics https://www.phenogenomics.cz/2026/01/bridging-the-gap-between-genes-and-therapy/ Bridging the Gap Between Genes and Therapy - Czech Centre for Phenogenomics Jan 14, 2026 - Under the theme “For Users, With Users,” the conference reinforced CCP’s role not just as a service provider, but as a strategic hub for collaborative... czech centrebridginggapgenestherapy https://www.phenogenomics.cz/animal-models/animal-facility/ Animal Facility - Czech Centre for Phenogenomics The CCP animal facility contains five individual, fully separated breeding and experimental barrier areas as well as an autonomous quarantine area. czech centreanimalfacilityphenogenomics https://www.phenogenomics.cz/2026/03/project-gene-age-2-0/ Project GENE AGE 2.0 - Czech Centre for Phenogenomics Mar 16, 2026 - The Gene Age 2.0 project brings together patients, patient organizations and scientists to find ways to explain scientific and health topics to the public in a… czech centreprojectgeneagephenogenomics https://www.phenogenomics.cz/phenotyping/hearing-and-electrophysiology/ Electrophysiology - Czech Centre for Phenogenomics Electrophysiological approaches provide sensitive, real-time readouts of neural and sensory system function across multiple levels of biological organization. czech centreelectrophysiologyphenogenomics https://chtp.ubc.ca/ Home | Centre for High-Throughput Phenogenomics The Centre for High-Throughput Phenogenomics offers a comprehensive suite of imaging technologies. Our goal is to provide multi-dimensional information and... high throughputcentrephenogenomics https://www.phenogenomics.cz/rare-diseases/harlequin-ichthyosis/ Harlequin Ichthyosis - Czech Centre for Phenogenomics Pathogenic mechanisms ABCA12 carries lipids, ceramides, cholesterol and fatty acids to the upper layer of epidermis – stratum corneum, through lamellar bodies. czech centreharlequinphenogenomics https://www.phenogenomics.cz/phenotyping/vision/ Vision - Czech Centre for Phenogenomics High-resolution SD-OCT enables quantitative, layer-resolved analysis of retinal morphology, including thickness, structural integrity… czech centrevisionphenogenomics https://www.phenogenomics.cz/rare-diseases/netherton-syndrome/ Netherton Syndrome - Czech Centre for Phenogenomics Pathogenic mechanisms Several organs co-express KLKs and LEKTI including those of the integumentary, respiratory, digestive, and immune systems. czech centrenethertonsyndromephenogenomics https://www.phenogenomics.cz/phenotyping/biostatistics-bioinformatics/ Biostatistics / Bioinformatics - Czech Centre for Phenogenomics The unit provides integrative bioinformatics support for phenotyping research, with a particular focus on large-scale analyses of metabolomics and... czech centrebiostatisticsbioinformaticsphenogenomics https://www.phenogenomics.cz/rare-diseases/canavan-disease/ Canavan Disease - Czech Centre for Phenogenomics Pathogenic mechanism Canavan disease is caused by mutations in the ASPA gene located on chromosome 17. This gene encodes the enzyme aspartoacylase… czech centrecanavandiseasephenogenomics https://www.ccp-conference.cz/ CCP Conference – CCP Phenogenomics Conference ccpconferencephenogenomics https://www.phenogenomics.cz/preclinical/standardized-modalities-and-key-services/ Available Standardized Modalities & Key Services - Czech Centre for Phenogenomics GLP certified services: Other available tests of the unit are also provided according to highly standardized protocols in GLP-like mode. GLP certified services… key servicesczech centreavailablestandardizedmodalities https://www.phenogenomics.cz/rare-diseases/hyperphosphatemic-familial-tumoral-calcinosis-hftc/ Hyperphosphatemic Familial Tumoral Calcinosis (HFTC) - Czech Centre for Phenogenomics Pathogenic mechanism HFTC is a rare autosomal recessive disease caused by mutations in genes involved in calcium and phosphate homeostasis and characterized by… czech centrefamilialphenogenomics https://www.phenogenomics.cz/events/ Events - Czech Centre for Phenogenomics czech centreeventsphenogenomics https://www.phenogenomics.cz/preclinical/cooperation-with-industry/ Cooperation with Industry - Czech Centre for Phenogenomics The work of CCP and its service portfolio is also very attractive for pro-profit organisation. Although CCP has started its phenotyping work only recently… czech centrecooperationindustryphenogenomics https://www.phenogenomics.cz/newsletter/phenogenomics-e-newsletter-2-2023/ Phenogenomics e-Newsletter 2/2023 - Czech Centre for Phenogenomics Aug 2, 2023 - The new state-of-the-art BSL-3 laboratory at the Czech Centre for Phenogenomics CCP preclinical services in a nutshell Focus on rare diseases: the Alliance for… czech centrephenogenomicsnewsletter https://www.phenogenomics.cz/preclinical-testing/implemented-preclinical-tests/ Preclinical Tests Already Implemented - Czech Centre for Phenogenomics High-risk infectious biological agents and toxins can be researched in the certified Biosafety Level 3 (BSL-3) laboratory. We provide experimental setting for… czech centrepreclinicaltestsalreadyimplemented https://www.phenogenomics.cz/phenotyping/database-of-impc-lines-created-at-ccp/ Database of IMPC Lines Created at CCP - Czech Centre for Phenogenomics czech centredatabaselinescreatedccp https://www.phenogenomics.cz/2026/01/from-genes-to-insights/ From Genes to Insights - Czech Centre for Phenogenomics Jan 14, 2026 - Over the past decade, the phenotyping at the Czech Centre for Phenogenomics (CCP) has undergone a profound transformation, mirroring the broader evolution of… czech centregenesinsightsphenogenomics https://www.phenogenomics.cz/rare-diseases/rd-activities/ Our RD-Activities - Czech Centre for Phenogenomics CCP: First RD in the program To initiate the program, CCP has established research and development projects on the following rare diseases: Preclinical… czech centrerdactivitiesphenogenomics https://www.phenogenomics.cz/phenotyping/neurobiology-and-behavior/ Neurobiology & Behavior - Czech Centre for Phenogenomics The Unit operates across multiple levels of behavioral analysis, from standardized screening to detailed phenotypic characterization of neurological traits. czech centreneurobiologybehaviorphenogenomics https://www.phenogenomics.cz/rare-diseases/pacs2-related-eidee/ PACS2-related EIDEE - Czech Centre for Phenogenomics Pathogenic mechanism PACS2-related EIDEE is a rare form of epilepsy caused by mutations in the PACS2 gene, which plays a key role in maintaining mitochondrial… czech centrerelatedphenogenomics https://www.phenogenomics.cz/phenotyping/pdx-and-cancer-models/ PDX & Cancer Models - Czech Centre for Phenogenomics The platform supports end-to-end experimental workflows, from tumor engraftment and expansion to longitudinal monitoring, multimodal phenotyping… czech centrepdxcancermodelsphenogenomics