https://www.tno.nl/en/healthy/efficient-drug-development/translational-preclinical-efficacy/
TNO has developed proven translational preclinical and early clinical models that offer predictive data in novel pharmaceutical and bioactive compounds.
translationalpreclinicalefficacymodelstno
https://www.gynepdx.com/
Bridging preclinical and clinical research for gynecological cancers. In Gyne PDX Platform, we design and conduct preclinical studies using our extensive...
preclinical modelsgynepdxplatform
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1404085/full
Immunotherapy holds great potential as a cornerstone of cancer treatment due to effective clinical outcomes. Ongoing research aims to enhance its efficacy an...
animal modelsfrontierseditorialchallengesassociated
https://pubmed.ncbi.nlm.nih.gov/41529908/
This study demonstrates, for the first time, the successful targeting of mCALR with CAR-T cells as a therapeutic strategy for MPNs. The chosen construct shows...
cell therapymutantcalreticulinenablespotent
https://www.businesswire.com/news/home/20250428558276/en/AACR-2025-Crown-Bioscience-Unveils-3D-Bone-Marrow-Niche-In-Vitro-Models-for-Oncology-Preclinical-Screening-in-Hematological-Malignancies
Crown Bioscience, a global contract research organization (CRO) headquartered in the United States and a part of JSR Life Sciences and Japan-based JSR Corpor...
crown biosciencebone marrowaacrunveilsniche
https://www.massgeneralbrigham.org/en/about/newsroom/press-releases/engineered-virus-boosts-immune-response-against-glioblastoma
Mass General Brigham researchers engineered a virus that destroys brain tumor cells while avoiding healthy brain tissue.
immune responsepreclinical modelsengineeredvirusboosts