Robuta

https://www.rcsb.org/structure/6HOV RCSB PDB - 6HOV: Crystal Structure of BRD4 first bromodomain in complex with ferulic acid Crystal Structure of BRD4 first bromodomain in complex with ferulic acid https://www.rcsb.org/structure/5F63 RCSB PDB - 5F63: Crystal structure of the first bromodomain of human BRD4 in complex with SG3-179 Crystal structure of the first bromodomain of human BRD4 in complex with SG3-179 https://www.ncbi.nlm.nih.gov/Structure/pdb/5D3S 5D3S: First bromodomain of BRD4 bound to inhibitor XD44 Bromodomain-containing protein 4(R,R)-2,3-BUTANEDIOL4-acetyl-3-ethyl-N-[4-fluoro-3-(morpholin-4-ylsulfonyl)phenyl]-5-methyl-1H-pyrrole-2-carboxamideDIMETHYL... firstbromodomainbrd4boundinhibitor https://www.mdpi.com/2305-6304/13/4/258 BRD4 Mediates Cadmium-Induced Oxidative Stress and Kidney Injury in Mice via Disruption of Redox... Cadmium (Cd) is a toxic heavy metal that threatens public health, with kidney injury being one of the common manifestations after Cd exposure. Oxidative stress... https://www.ncbi.nlm.nih.gov/Structure/pdb/6RWJ 6RWJ: Crystal Structure of BRD4(1) bound to inhibitor BUG0 (6) crystal structurebrd4 https://www.ncbi.nlm.nih.gov/Structure/pdb/3UVY 3UVY: Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated... Bromodomain-containing protein 4Histone H4 https://www.ncbi.nlm.nih.gov/Structure/pdb/5UEU 5UEU: BRD4_BD2_A-1107604 Bromodomain-containing protein 4methyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate brd4bd2 https://www.ncbi.nlm.nih.gov/Structure/pdb/7XFG 7XFG: NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif... Histone acetyltransferase p300NUT family member 1ZINC ION https://www.ncbi.nlm.nih.gov/Structure/pdb/6YQN 6YQN: Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor... Bromodomain-containing protein... https://www.ncbi.nlm.nih.gov/gene/126806429 LOC126806429 BRD4-independent group 4 enhancer GRCh37_chr2:179591393-179592592 [Homo sapiens... independent group https://www.rcsb.org/structure/6AJZ RCSB PDB - 6AJZ: Joint nentron and X-ray structure of BRD4 in complex with colchicin Joint nentron and X-ray structure of BRD4 in complex with colchicin https://www.deutsche-digitale-bibliothek.de/item/Y54ALIO5SVQJYMCB43M7KVCRNBJYSRRW Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion -... https://www.semanticscholar.org/topic/BRD4-C15orf55-Fusion-Gene/1255149 BRD4/C15orf55 Fusion Gene | Semantic Scholar A fusion gene (~6 kb) that results from a chromosomal translocation t(15;19)(q14;p13) which fuses the first 10 exons of the BRD4 gene with exon 2 of the NUTM1... fusion genebrd4semanticscholar https://www.ebi.ac.uk/chembl/explore/document/CHEMBL2434916 Document: Discovery of novel small-molecule inhibitors of BRD4 using structure-based virtual... Report card for Document Discovery of novel small-molecule inhibitors of BRD4 using structure-based virtual screening. (CHEMBL2434916). J Med Chem,... discovery ofsmall molecule https://www.rcsb.org/structure/4LR6 RCSB PDB - 4LR6: Structure of BRD4 bromodomain 1 with a 3-methyl-4-phenylisoxazol-5-amine fragment Structure of BRD4 bromodomain 1 with a 3-methyl-4-phenylisoxazol-5-amine fragment https://www.rcsb.org/structure/6KO2 RCSB PDB - 6KO2: Crystal Structure of BRD4-Brmo2 in complex with H2A.ZK4acK7ac peptide Crystal Structure of BRD4-Brmo2 in complex with H2A.ZK4acK7ac peptide https://www.deutsche-digitale-bibliothek.de/item/D43J2RWKFPIOGP4XVZ746S6AGVSBRUY6 Influence of shear stress, inflammation and BRD4 inhibition on human endothelial cells: a holistic... https://www.rcsb.org/structure/2YEL RCSB PDB - 2YEL: Crystal Structure of the First Bromodomain of Human Brd4 with the inhibitor... Crystal Structure of the First Bromodomain of Human Brd4 with the inhibitor GW841819X https://www.ncbi.nlm.nih.gov/Structure/pdb/4Z1S 4Z1S: Crystal structure of the first bromodomain of human BRD4 with benzotriazolo-diazepine scaffold Bromodomain-containing protein 45-[(4S)-6-(4-chlorophenyl)-1,4-dimethyl-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-8-yl]pyridin-2-amine https://www.ncbi.nlm.nih.gov/Structure/pdb/8IDH 8IDH: Bromodomain and Extra-terminal Domain (BET) BRD4 bromodomainextraterminalbetbrd4 https://www.rcsb.org/structure/5M3A RCSB PDB - 5M3A: Crystal structure of BRD4 BROMODOMAIN 1 IN COMPLEX WITH LIGAND 2 Crystal structure of BRD4 BROMODOMAIN 1 IN COMPLEX WITH LIGAND 2 https://www.ncbi.nlm.nih.gov/Structure/pdb/4XY9 4XY9: Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-amine-9H-purine... Bromodomain-containing protein 41,2-ETHANEDIOL6-(5-bromo-2-methoxyphenyl)-9H-purin-2-amine https://www.ncbi.nlm.nih.gov/Structure/pdb/8FVK 8FVK: First bromodomain of BRD4 liganded with CCS-1477 Bromodomain-containing protein... firstbromodomainbrd4ccs1477 https://www.ncbi.nlm.nih.gov/gene/57261 Brd4 bromodomain containing 4 [Mus musculus (house mouse)] - Gene - NCBI mus musculushouse mousebrd4bromodomaincontaining https://www.rcsb.org/structure/5D3S RCSB PDB - 5D3S: First bromodomain of BRD4 bound to inhibitor XD44 First bromodomain of BRD4 bound to inhibitor XD44 rcsb pdbfirstbromodomain https://www.ncbi.nlm.nih.gov/Structure/pdb/4UIZ 4UIZ: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH... BROMODOMAIN-CONTAINING PROTEIN 41,2-ETHANEDIOL7-(3,4-dimethoxyphenyl)-5-methyl-2-(4-methylsulfonylpiperazin-1-yl)carbonyl-thieno[3,2-c]pyridin-4-one n terminalbromodomainhumanbrd4 https://www.ncbi.nlm.nih.gov/Structure/pdb/6JJB 6JJB: BRD4 in complex with ZZM1 Bromodomain-containing protein 42-methoxy-N-(1-methyl-2-oxidanylidene-benzo[cd]indol-6-yl)benzenesulfonamide brd4complex https://www.deutsche-digitale-bibliothek.de/item/XXXIITANVVBJTAF2DCYNVEFBOHN3NE2M Super-enhancers and the super-enhancer reader BRD4: tumorigenic factors and therapeutic targets -... superenhancers https://www.rcsb.org/structure/6JI5 RCSB PDB - 6JI5: brd4-bd1 bound with ligand 167 brd4-bd1 bound with ligand 167 rcsb pdbbrd4bd1boundligand https://www.ncbi.nlm.nih.gov/protein/8ZMB_A Chain A, BRD4_HUMAN - Protein - NCBI chainbrd4humanproteinncbi https://www.rcsb.org/structure/7DHS RCSB PDB - 7DHS: Crystal Structure Analysis of the BRD4 Crystal Structure Analysis of the BRD4 rcsb pdbcrystal structureof theanalysisbrd4 https://www.rcsb.org/structure/5T35 RCSB PDB - 5T35: The PROTAC MZ1 in complex with the second bromodomain of Brd4 and... The PROTAC MZ1 in complex with the second bromodomain of Brd4 and pVHL:ElonginC:ElonginB https://www.rcsb.org/structure/5UEP RCSB PDB - 5UEP: BRD4_BD2_A-581577 rcsb pdbbrd4bd2 https://www.rcsb.org/structure/2NCZ RCSB PDB - 2NCZ: Solution NMR structures of BRD4 ET domain in complex with NSD3_1 peptide Solution NMR structures of BRD4 ET domain in complex with NSD3_1 peptide https://www.rcsb.org/structure/7MLS RCSB PDB - 7MLS: X-ray crystal structure of human BRD4(D1) in complex with... X-ray crystal structure of human BRD4(D1) in complex with 2-(2,5-dibromophenoxy)-6-[4-methyl-1-(piperidin-4-yl)-1H-1,2,3-triazol-5-yl]pyridine (compound 23) x ray crystal structure https://www.rcsb.org/structure/5EIS RCSB PDB - 5EIS: FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR... FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 3-(4-Chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione https://www.ncbi.nlm.nih.gov/Structure/pdb/8B96 8B96: Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5464 Bromodomain-containing protein 41,2-ETHANEDIOLDIMETHYL... https://www.rcsb.org/structure/6SAJ RCSB PDB - 6SAJ: Crystal Structure of BRD4(1) bound to inhibitor BUX6 (12) Crystal Structure of BRD4(1) bound to inhibitor BUX6 (12) https://www.businesswire.com/news/home/20241003282671/en/DeepCure-to-Present-In-Vivo-Data-Showing-Its-Selective-BRD4-BD2-Inhibitor-DC-9476-is-Superior-to-Etanercept-in-Rheumatoid-Arthritis DeepCure to Present In Vivo Data Showing Its Selective BRD4 (BD2) Inhibitor DC-9476 is Superior to... DeepCure to Present In Vivo Data Showing Its Selective BRD4 (BD2) Inhibitor DC-9476 is Superior to Etanercept in Rheumatoid Arthritis https://www.rcsb.org/structure/5I80 RCSB PDB - 5I80: BRD4 in complex with Cpd2... BRD4 in complex with Cpd2 (N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide) rcsb pdbbrd4complexcpd2