https://elifesciences.org/articles/90221
BRAIDing receptors for cell-specific targeting | eLife
A novel strategy to activate the WNT pathway in a cell type selective manner by linking designer ligands with target cell specific bridging receptors.
cell specificbraidingreceptorstargetingelife
https://pmc.ncbi.nlm.nih.gov/articles/PMC3633693/
PMEL: A PIGMENT CELL-SPECIFIC MODEL FOR FUNCTIONAL AMYLOID FORMATION - PMC
PMEL is a pigment cell-specific protein responsible for the formation of fibrillar sheets within the pigment organelle, the melanosome. The fibrillar sheets...
pigment cellpmelspecific
https://pmc.ncbi.nlm.nih.gov/articles/PMC21774/
Identification of a photoreceptor cell-specific nuclear receptor - PMC
Nuclear receptors comprise a large and expanding family of transcription factors involved in diverse aspects of animal physiology and development, the...
of aphotoreceptor cellidentificationspecificnuclear
https://pmc.ncbi.nlm.nih.gov/articles/PMC7995302/
Cryopreservation: An Overview of Principles and Cell-Specific Considerations - PMC
The origins of low-temperature tissue storage research date back to the late 1800s. Over half a century later, osmotic stress was revealed to be a main...
an overviewcell specificcryopreservationprinciplesconsiderations
https://www.thebusinessresearchcompany.com/report/t-cell-specific-surface-glycoprotein-cd28-global-market-report
T Cell Specific Surface Glycoprotein CD28 Market Size 2026
T cell specific surface glycoprotein cd28 market to reach $2.58 billion by 2030 at 9.7% CAGR, driven by growing emphasis on personalized medicine approaches.
t cellspecific surfacemarket sizeglycoproteincd28
https://www.news-medical.net/news/20090806/Reversible-cell-specific-drug-delivery-with-aptamer-functionalized-liposomes.aspx
Reversible cell-specific drug delivery with aptamer-functionalized liposomes
Jun 19, 2019 - For cancer drug developers, finding an agent that kills tumor cells is only part of the equation. The drug must also spare healthy cells, and - ideally - its...
reversible celldrug deliveryspecificaptamerfunctionalized
https://elifesciences.org/articles/106686
Neuronal Signaling: Cell-specific tools for understanding behavior | eLife
Novel tools that allow neuron-specific investigations of the structure controlling sleep regulation in fruit flies reveal the extent of neuronal heterogeneity.
neuronal signalingcell specifictoolsunderstandingbehavior
https://www.wikidata.org/wiki/Q39947306
Adenovirus-infected, Cell-specific, DNA-binding Proteins - Wikidata
scientific article published on January 1, 1975
dna binding proteinscell specificadenovirusinfectedwikidata
https://pmc.ncbi.nlm.nih.gov/articles/PMC46255/
Cell-specific regulation of apoptosis by designed enediynes - PMC
The naturally occurring enediyne antibiotics are a unique class of antitumor drugs that combine reactive enediynes with additional structural features...
regulation of apoptosiscell specificdesignedenediynespmc
https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1230942/full
Frontiers | Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal...
The diagnosis of epilepsy is complex and challenging and would benefit from the availability of molecular biomarkers, ideally measurable in a biofluid such a...
brain cell
https://www.wikidata.org/wiki/Q44689071
Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor...
a cellhomeotic gene
https://www.wikidata.org/wiki/Q24651446
B-cell-specific DNA binding by an E47 homodimer - Wikidata
b celldna bindingspecifice47homodimer
https://elifesciences.org/articles/62293
Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures | eLife
Comprehensive single-cell transcriptome analysis reveals global and tissue-specific aging markers and characterizes the heterogeneous aging status of different...
aging cell
https://pmc.ncbi.nlm.nih.gov/articles/PMC5125880/
Detection of Herpes Simplex Virus Type 2 (HSV-2) -Specific Cell-Mediated Immune Responses in Guinea...
Genital infections with herpes simplex virus type 2 (HSV-2) are a source of considerable morbidity and are a health concern for newborns exposed to virus...
herpes simplex virus type 2
https://elifesciences.org/reviewed-preprints/97416
Intracellular mechanical fingerprint reveals cell type specific mechanical tuning
mechanical fingerprintcell typeintracellularrevealsspecific
https://elifesciences.org/reviewed-preprints/94698
Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by...
https://elifesciences.org/articles/56782
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma | eLife
Isotope tracing into macromolecules enables functional analysis of metabolism in specific cell populations in tumors and provides insight into metabolic...
cell typedissectingspecificmetabolismpancreatic
https://www.wikidata.org/wiki/Q40991946
Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern...
scientific article published on December 1998
https://elifesciences.org/articles/51452
Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by...
Probe-Seq is a cell type specific bulk RNA sequencing method that can be applied to a wide-ranging tissue types from both vertebrates and invertebrates without...
https://www.wikidata.org/wiki/Q36272656
Specific murine B-cell activation by synthetic single-and double-stranded polynucleotides - Wikidata
scientific article published on December 1, 1973
b cell activation
https://www.jci.org/assets/235116/powerpoint
JCI - HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation
https://www.stjude.org/care-treatment/clinical-trials/3car-solid-tumor.html
3CAR: B7-H3-specific CAR T-cell Therapy for Children and Young Adults with Solid Tumors | St. Jude...
A clinical trial to study the use of B7-H3-specific CAR T-cell therapy for children and young adults with relapsed or refractory solid tumors. Learn more.
https://pmc.ncbi.nlm.nih.gov/articles/PMC43819/
Glial-specific cAMP response of the glial fibrillary acidic protein gene cell lines - PMC
Expression of the rat glial fibrillary acidic protein (GFAP) gene is responsive to the intracellular level of cAMP. We have examined the sequence 5'-upstream...
https://elifesciences.org/reviewed-preprints/110672
Calibrated analysis framework for nanopore direct RNA sequencing uncovers cell-specific m6A...
direct rna sequencinganalysis framework
https://pmc.ncbi.nlm.nih.gov/articles/PMC8744330/
The landscape of human tissue and cell type specific expression and co-regulation of senescence...
Cellular senescence is a complex stress response that impacts cellular function and organismal health. Multiple developmental and environmental factors, such...
https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2025.1608889/full
Frontiers | Cell specific perfusion rates drive growth dynamics and metabolism in CHO N-1 perfusion...
The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cell host systems often faces challenges in terms of manufacturing costs and...
https://www.jci.org/articles/view/163541/sd/2
JCI - Chronic graft-versus-host disease detected by tissue-specific cell-free DNA methylation...
graft versus host disease
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.942192/full
Frontiers | Divergent SARS-CoV-2-specific T cell responses in intensive care unit workers following...
The cellular immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in response to full mRNA COVID-19 vaccination could be variable ...
https://www.wikidata.org/wiki/Q40649512
The induction of carrier-specific helper cell tolerance in presensitized rats - Wikidata
scientific article published on May 1, 1977
helper cell
https://elifesciences.org/articles/08145/figures
Figures and data in Asymmetric division triggers cell-specific gene expression through coupled...
Asymmetric cell division is linked to cell-specific transcription by handoff of a key developmental regulator from the cytokinetic machinery to the adjacent...
figures and data
https://elifesciences.org/articles/62293/peer-reviews
Peer review in Mouse aging cell atlas analysis reveals global and cell type-specific aging...
Comprehensive single-cell transcriptome analysis reveals global and tissue-specific aging markers and characterizes the heterogeneous aging status of different...
https://www.spandidos-publications.com/10.3892/mco.2015.568
Plasma neuron-specific enolase level as a prognostic marker in patients with non-small cell lung...
International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.
https://www.jci.org/articles/view/163541/figure/1
JCI - Chronic graft-versus-host disease detected by tissue-specific cell-free DNA methylation...
graft versus host disease
https://elifesciences.org/articles/46876
Cell-type specific innervation of cortical pyramidal cells at their apical dendrites | eLife
The composition of inhibitory and excitatory synaptic inputs to the apical dendrites of pyramidal cells in mouse cortex is specific to the type of pyramidal...
https://pmc.ncbi.nlm.nih.gov/articles/PMC8860836/
Cell-Type Specific Deletion of CB2 Cannabinoid Receptors in Dopamine Neurons Induced Hyperactivity...
DAT-Cnr2 mice are conditional knockout (cKO) animals that do not express cannabinoid CB2 receptors (CB2R), in midbrain dopamine neurons. The hyperactivity...
https://pmc.ncbi.nlm.nih.gov/articles/PMC4228834/
In utero hematopoietic cell transplantation: induction of donor specific immune tolerance and...
In utero hematopoietic cell transplantation (IUHCT) is a non-myeloablative non-immunosuppressive transplant approach that allows for donor cell engraftment...
in uterohematopoietic cell
https://www.jci.org/articles/view/39608/table/1
JCI - Antigen-specific Tregs control T cell responses against a limited repertoire of tumor...
https://elifesciences.org/articles/50564/peer-reviews
Peer review in Large-scale cell-type-specific imaging of protein synthesis in a vertebrate brain |...
The development of a transgenic zebrafish allows for cell-type-specific labeling of neuronal protein synthesis, enabling brain-wide visualization and...
https://elifesciences.org/articles/22039/figures
Figures and data in Mapping cell type-specific transcriptional enhancers using high affinity,...
A method for measuring p300 chromatin occupancy in specific lineages of mouse tissues was used to map endothelial enhancers and to identify previously...
figures and data
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2019.00298/full
Frontiers | Antibody Specific B-Cell Epitope Predictions: Leveraging Information From...
B-cells can neutralize pathogenic molecules by targeting them with extreme specificity using receptors secreted or expressed on their surface (antibodies). T...
b cellfrontiersantibodyspecificepitope
https://www.jci.org/articles/view/113383/scanned-page/777
JCI - Schistosoma japonicum egg antigen-specific T cell lines in man. Induction of helper and...
https://www.jci.org/articles/view/113383/scanned-page/778
JCI - Schistosoma japonicum egg antigen-specific T cell lines in man. Induction of helper and...
https://www.wikidata.org/wiki/Q36353340
Antigen presentation by chemically modified splenocytes induces antigen-specific T cell...
antigen presentationchemicallymodifiedinducesspecific
https://www.greatbay-bio.com/
Great Bay Bio - AI-enabled CMC + Site-Specific Integration Cell Line Development + Antibody Drug...
Great Bay Bio (GBB), headquartered in HKSTP, is a biotech company that drives drug development using cutting-edge technologies such as AI, big data mining, and...
https://www.sciencealert.com/activating-one-specific-brain-cell-extended-lifespan-in-mice-by-70-days
Activating One Specific Brain Cell Extended Lifespan in Mice by 70 Days : ScienceAlert
Jan 11, 2024 - Aging might have advantages in wisdom, experience, and even evolution, but the gradual breakdown of biology that comes with growing old is rarely much fun for...
https://elifesciences.org/articles/51350
Insights into the dynamic control of breathing revealed through cell-type-specific responses to...
The neuromodulator substance P enhances mechanisms of recurrent excitation between breaths to control breathing frequency and stability.
https://www.fda.gov/about-fda/oncology-center-excellence/integrative-proteogenomics-elucidation-tumor-specific-cell-surface-proteomes-ultra-rare-cancers
Integrative Proteogenomics for Elucidation of Tumor-specific Cell Surface Proteomes in Ultra-rare...
Description of an FDA Oncology Center of Excellence funded extramural research project.
https://pmc.ncbi.nlm.nih.gov/articles/PMC15972/
Isolation of a vascular cell wall-specific monoclonal antibody recognizing a cell polarity by using...
Using a strategy consisting of (i) the isolation of cell walls from synchronously differentiating cells of Zinnia, (ii) the generation of mAbs with an antibody...
https://pmc.ncbi.nlm.nih.gov/articles/PMC1273861/
A Strong Antigen-Specific T-Cell Response Is Associated with Age and Genetically Dependent...
Chicken genetics and age affect resistance to enteric infection with Salmonella enterica serovar Typhimurium and were used to identify the immune responses...
https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2017.00061/full
Frontiers | Increased Potency of a Bi-specific TL1A-ADAM17 (TACE) Inhibitor by Cell Surface...
Inflammatory bowel disease (IBD) is a multifactorial disease characterized by the dysregulated activity of many pro-inflammatory factors. Thus, bi-specific i...
https://www.preprints.org/manuscript/202108.0492
A T-Cell Epitope-Based Multi-Epitope Vaccine Designed Using Human HLA Specific T Cell Epitopes...
Visceral Leishmaniasis is a neglected tropical disease affecting 12 million people annually. Even in the second decade of the 21st century, it has remained...
https://www.jci.org/articles/view/39608/usage
JCI - Usage information: Antigen-specific Tregs control T cell responses against a limited...
https://pmc.ncbi.nlm.nih.gov/articles/PMC22739/
Cell-specific viral targeting mediated by a soluble retroviral receptor-ligand fusion protein - PMC
TVA, the cellular receptor for subgroup A avian leukosis viruses (ALV-A) can mediate viral entry when expressed as a transmembrane protein or as a...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.03153/full
Frontiers | A Novel T-Cell Engaging Bi-specific Antibody Targeting the Leukemia Antigen PR1/HLA-A2
Despite substantial advances in the treatment of acute myeloid leukemia (AML), only 30% of patients survive more than 5 years. Therefore, new therapeutics ar...
https://www.news-medical.net/news/20251124/Study-uncovers-how-a-specific-immune-cell-may-contribute-to-HIV-persistence.aspx
Study uncovers how a specific immune cell may contribute to HIV persistence
Nov 25, 2025 - Researchers from the Institute of Human Virology (IHV) at the University of Maryland School of Medicine have discovered how a specific type of immune cell may...
immune cell
https://pmc.ncbi.nlm.nih.gov/articles/PMC7978494/
Disease-in-a-Dish: The Contribution of Patient-specific Induced Pluripotent Stem Cell Technology to...
Advances in regenerative medicine technologies will lead to dramatic changes in how patients in rehabilitation medicine clinics are treated in the upcoming...
https://elifesciences.org/articles/72549
Cell-type-specific responses to associative learning in the primary motor cortex | eLife
Major neuronal subtypes in M1 show differential responses to reward and reward-associated stimuli and undergo cell-type-specific plasticity following...
https://pmc.ncbi.nlm.nih.gov/articles/PMC23354/
Expression of HLA class I-specific inhibitory natural killer cell receptors in HIV-specific...
Human T lymphocytes have been shown to express inhibitory natural killer cell receptors (NKR), which can down-regulate T cell antigen receptor-mediated T cell...
natural killer cell receptors
https://case.edu/cancer/about-us/news/myeloid-derived-suppressor-cell-heterogeneity-comprises-sex-specific-therapeutic-target-glioblastoma
Myeloid-derived Suppressor Cell Heterogeneity Comprises a Sex-specific Therapeutic Target for...
Aug 31, 2021 - A study led by Justin D. Lathia, PhD (Bayik et al., Cancer Discovery, 2020) and conducted in collaboration with multiple Case Comprehensive Cancer Cen...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1340645/full
Frontiers | Long-term analysis of humoral responses and spike-specific T cell memory to Omicron...
Background: The emergence of SARS-CoV-2 variants has raised concerns about the sustainability of vaccine-induced immunity. Little is known about the long-ter...
https://www.birmingham.ac.uk/news-archive/2021/specific-cell-population-plays-a-key-role-in-the-affect-arthritis-has-on-the-body-and-the-pain-patients-feel-study-finds-4
Specific cell population plays a key role in the affect arthritis has on the body and the pain...
A new study has identified a new specific population of cells that plays a key role in the affect arthritis has on the body and the subsequent pain felt by...
https://www.sciencedaily.com/releases/2019/05/190516142900.htm
Brain changes in autism traced to specific cell types | ScienceDaily
Changes in gene activity in specific brain cells are associated with the severity of autism in children and young adults with the disorder, according to a new...
brain changescell typesautismtracedspecific
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.662444/full
Frontiers | siRNAs Targeting Mouse-Specific lncRNA AA388235 Induce Human Tumor Cell...
Species-specific lncRNAs significantly determine species-specific functions through various ways, such as epigenetic regulation. However, there has been no s...
human tumorfrontierssirnastargetingmouse
https://www.jci.org/articles/view/39608/citations
JCI - Citations to Antigen-specific Tregs control T cell responses against a limited repertoire of...
https://www.mdpi.com/1999-4915/13/5/916
Persistent COVID-19 Symptoms Minimally Impact the Development of SARS-CoV-2-Specific T Cell Immunity
SARS-CoV-2 represents an unprecedented public health challenge. While the majority of SARS-CoV-2-infected individuals with mild-to-moderate COVID-19 resolve...
https://elifesciences.org/articles/10206/figures
Figures and data in Cell type-specific pharmacology of NMDA receptors using masked MK801 | eLife
The small molecule NMDA-receptor antagonist MK801 has been genetically targeted to specific cell types in brain tissue to examine the role of NMDA receptors in...
https://www.jci.org/articles/view/39608/figure/4
JCI - Antigen-specific Tregs control T cell responses against a limited repertoire of tumor...
https://www.wikidata.org/wiki/Q36530603
A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell...
scientific article published on December 1991
https://elifesciences.org/reviewed-preprints/88936
Detection of new pioneer transcription factors as cell-type specific nucleosome binders
transcription factors
https://www.wikidata.org/wiki/Q59067678
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins - Wikidata
scientific article published on March 8, 1984
cdna clonest cell
https://elifesciences.org/articles/36204
Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity | eLife
Functional molecular analysis of cytokinesis in Caenorhabditis elegans four-cell embryos reveals cell-type-specific variation in the fundamental dependence on...
cellintrinsicextrinsicmechanisms
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.657144/full
Frontiers | Is It Feasible to Use CMV-Specific T-Cell Adoptive Transfer as Treatment Against...
During the last decade, many studies have demonstrated the role of CMV specific T-cell immune response on controlling CMV replication and dissemination. In f...
https://www.mdpi.com/1999-4915/14/6/1172
Identification of NP Protein-Specific B-Cell Epitopes for H9N2 Subtype of Avian Influenza Virus
Avian Influenza (AI) caused by the H9N2 subtype of the avian influenza virus (AIV) poses a serious threat to both the poultry industry and to public health...
https://elifesciences.org/articles/14985
Behavioral-state modulation of inhibition is context-dependent and cell type specific in mouse...
The three main types of inhibitory neurons in mouse primary visual cortex respond differently to locomotion in darkness and during visual stimulation,...
https://elifesciences.org/reviewed-preprints/97416v1/figures
Intracellular mechanical fingerprint reveals cell type specific mechanical tuning
mechanical fingerprintcell typeintracellularrevealsspecific