checkpoint inhibitors - Robuta Search

https://www.cancer.gov/about-cancer/treatment/types/immunotherapy/checkpoint-inhibitors?ref=mackenziemorehead.com Immune Checkpoint Inhibitors - NCI Immune checkpoint inhibitors are a type of immunotherapy that block immune checkpoint proteins from binding with partner proteins. Learn about the cancers... immune checkpoint inhibitors nci https://researchconnect.buffalo.edu/en/publications/responses-to-immune-checkpoint-inhibitors-in-nonagenarians/ Responses to immune checkpoint inhibitors in nonagenarians - SUNY University at Buffalo immune checkpoint inhibitors responses https://pubmed.ncbi.nlm.nih.gov/39674302/ Central nervous system complications of immune checkpoint inhibitors: A comprehensive review The ever-increasing use of immune checkpoint inhibitors (ICIs) has significantly improved cancer management, but at the cost of frequent immunologic side... central nervous system immune checkpoint inhibitors complications https://pmc.ncbi.nlm.nih.gov/articles/PMC12714540/ Infusion-Related Reactions Among Cancer Patients Receiving Immune Checkpoint Inhibitors: The... To investigate the incidence of Infusion-Related Reactions (IRRs) among cancer patients receiving Immune Checkpoint Inhibitors (ICIs) and immune-based... immune checkpoint inhibitors cancer patients infusion related reactions https://pmc.ncbi.nlm.nih.gov/articles/PMC9189307/ Overview of Checkpoint Inhibitors Mechanism of Action: Role of Immune-Related Adverse Events and... In recent years, immunotherapy-based regimens have been included into the treatment's algorithm of several cancer types. Programmed death-1 (PD-1) and... overview of checkpoint inhibitors action role https://experts.arizona.edu/en/publications/immune-checkpoint-inhibitors-and-immune-related-adverse-events-in/ Immune Checkpoint Inhibitors and Immune-Related Adverse Events in Patients with Advanced Melanoma:... immune checkpoint inhibitors adverse events https://pmc.ncbi.nlm.nih.gov/articles/PMC5925139/ Immune Checkpoint Inhibitors to Treat Malignant Lymphomas - PMC Genetic and/or epigenetic changes provide antigen-derived diversity in neoplastic cells. Beside, these cells do not initiate immune response of host organisms.... immune checkpoint inhibitors malignant lymphomas treat pmc https://www.mdpi.com/2077-0383/12/5/1757 The Evolving Role of Immune-Checkpoint Inhibitors in Malignant Pleural Mesothelioma Malignant pleural mesothelioma (MPM) is a rare cancer usually caused by asbestos exposure and associated with a very poor prognosis. After more than a decade... immune checkpoint inhibitors evolving role https://www.news-medical.net/life-sciences/How-Immune-Checkpoint-Inhibitors-have-Revolutionized-Cancer-Treatment.aspx How Immune Checkpoint Inhibitors have Revolutionized Cancer Treatment Mar 11, 2020 - Immune checkpoint inhibitors have emerged as a revolutionary type of cancer immunotherapy. immune checkpoint inhibitors revolutionized cancer treatment https://scholars.duke.edu/publication/1623813 Scholars@Duke publication: Immune Checkpoint Inhibitors in Geriatric Oncology. immune checkpoint inhibitors scholars duke publication geriatric https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1476475/full Frontiers | Editorial: Immune-checkpoint inhibitors in anti-cancer armamentarium: a double-edged... AEs depends on the specific ICI drug, with anti-PD-1/anti-PD-L1 monotherapy linked with greater incidence compared to anti-CTLA-4 treatment, and atezolizumab... immune checkpoint inhibitors https://infoscience.epfl.ch/entities/publication/ff5f5806-78c0-4abc-9b50-45fa856c21a1 Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance Immune-checkpoint inhibitors (ICIs), including anti-cytotoxic T lymphocyte antigen 4 (CTLA-4), anti-programmed cell death 1 (PD-1) and anti-programmed cell... immune checkpoint inhibitors adverse effects epidemiology management surveillance https://pubmed.ncbi.nlm.nih.gov/29951303/ Immune-related adverse events with immune checkpoint inhibitors in thoracic malignancies: focusing... Immune checkpoint inhibitors (ICIs) have revolutionized treatment landscape among non-small cell lung cancer (NSCLC) patients in first- and second-line... adverse events checkpoint inhibitors immune related https://publikationen.uni-tuebingen.de/xmlui/handle/10900/129844 Combination of immune checkpoint inhibitors and tyrosine kinase inhibitors for the treatment of... immune checkpoint inhibitors tyrosine kinase for the combination https://pubmed.ncbi.nlm.nih.gov/41912473/ A Disproportionality Analysis of Immune Checkpoint Inhibitors in Combination With Platinum-Based... The combination exhibits distinct early-onset toxicities (early-onset hematological/endocrine/hepatic) and novel risks (neuropathy/myocarditis/leukemia),... immune checkpoint inhibitors https://clarivate.com/life-sciences-healthcare/report/acreon0035-2018-biopharma-immune-checkpoint-inhibitors-access-and-reimbursement-us-2018/ Immune Checkpoint Inhibitors | Access and Reimbursement | US | 2018 | Clarivate Immune checkpoint inhibitors have revolutionized the treatment of multiple oncology indications, but the high costs associated with these agents present... immune checkpoint inhibitors access reimbursement us clarivate https://pubmed.ncbi.nlm.nih.gov/41165703/ Immune Checkpoint Inhibitors as Independent and Synergistic Drivers of SJS/TEN Immune Checkpoint Inhibitors as Independent and Synergistic Drivers of SJS/TEN immune checkpoint inhibitors independent https://pubmed.ncbi.nlm.nih.gov/38927951/ Toxicity-Induced Discontinuation of Immune Checkpoint Inhibitors in Metastatic Urothelial Cancer:... Immune checkpoint inhibitor (ICI) therapies have been established as the standard-of-care in various uro-oncological cancers. Immune-related adverse events... immune checkpoint inhibitors toxicity induced discontinuation https://researchconnect.buffalo.edu/en/publications/toxicities-in-immune-checkpoint-inhibitors/ Toxicities in Immune Checkpoint Inhibitors - SUNY University at Buffalo immune checkpoint inhibitors suny university buffalo https://www.techtransfer.nih.gov/patent/e-148-2021-0-pct-02 COMPOSITIONS AND METHODS FOR DETERMINING RESPONSIVENESS TO IMMUNE CHECKPOINT INHIBITORS (ICI),... immune checkpoint inhibitors compositions methods determining https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1397053/full Frontiers | Immune checkpoint inhibitors in advanced and relapsed/refractory Hodgkin lymphoma:... Classic Hodgkin lymphoma (cHL) treatment paradigms are undergoing a shift with the integration of immune checkpoint inhibitors (ICIs) into both first-line an... immune checkpoint inhibitors frontiers https://pubmed.ncbi.nlm.nih.gov/31118078/ Neurologic toxicity associated with immune checkpoint inhibitors: a pharmacovigilance study ICIs produce a spectrum of distinct classes of neurologic AEs that can cause significant morbidity and mortality and tend to occur early and with... immune checkpoint inhibitors associated with neurologic toxicity pharmacovigilance https://www.news-medical.net/news/20190118/Immune-checkpoint-inhibitors-induce-rheumatic-disease-and-musculoskeletal-diseases.aspx Immune checkpoint inhibitors induce rheumatic and musculoskeletal diseases Jan 20, 2019 - Checkpoint inhibitor therapy is a form of cancer treatment immunotherapy currently under research. The therapy targets immune checkpoints, key regulators of... immune checkpoint inhibitors induce musculoskeletal diseases https://pubmed.ncbi.nlm.nih.gov/36706163/ Immune Checkpoint Inhibitors in Solid Organ Transplant Recipients With Advanced Skin... Use of immune checkpoint inhibitors (ICIs) in solid organ transplant recipients (SOTRs) with advanced skin cancers presents a significant clinical management... immune checkpoint inhibitors organ transplant solid https://scholars.duke.edu/publication/1655061 Scholars@Duke publication: Immune checkpoint inhibitors for glioblastoma: emerging science,... immune checkpoint inhibitors scholars duke publication glioblastoma https://adisinsight.springer.com/trials/700324299?error=cookies_not_supported&code=e7d6e0cc-582f-4e3f-bab1-018fbcc138d1 Retrospective review of patients treated with Checkpoint Inhibitors - AdisInsight To describe the clinical, biological, and radiological features of the largest cohort of rheumatic irAEs from ICI along with their therapeutic management, retrospective review checkpoint inhibitors patients treated adisinsight https://www.techtransfer.nih.gov/patent/e-148-2021-0-us-01 COMPOSITIONS AND METHODS FOR DETERMINING RESPONSIVENESS TO IMMUNE CHECKPOINT INHIBITORS (ICI),... immune checkpoint inhibitors compositions methods determining https://adisinsight.springer.com/drugsafety/803926827?error=cookies_not_supported&code=e1092de1-6266-4c71-a365-510847fa2ad9 Immune checkpoint protein inhibitors - AdisInsight Thirty-one patients with advanced hepatocellular carcinoma received immune checkpoint inhibitors and experienced adverse events including appetite loss and immune checkpoint protein inhibitors adisinsight https://boris-portal.unibe.ch/entities/publication/2d76bb1e-8033-4390-b195-4a8861783c9c Late-onset and long-lasting immune-related adverse events from immune checkpoint-inhibitors: An... BACKGROUND Immune checkpoint inhibitors (ICIs) have revolutionised cancer therapy but frequently cause immune-related adverse events (irAEs). Description of... https://pmc.ncbi.nlm.nih.gov/articles/PMC8831742/ Cytokine Release Syndrome in Cancer Patients Receiving Immune Checkpoint Inhibitors: A Case Series... Cytokine release syndrome (CRS) is a phenomenon of immune hyperactivation described in the setting of immunotherapy. Unlike other immune-related adverse... cytokine release syndrome immune checkpoint inhibitors https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1130238/full Frontiers | Ophthalmic immune-related adverse events associated with immune checkpoint inhibitors Purpose: To investigate the incidence of immune-related adverse events (irAEs) of immune checkpoint inhibitor (ICI) therapy and to report the clinical featur... adverse events associated with frontiers ophthalmic immune https://pubmed.ncbi.nlm.nih.gov/31202955/ Tyrosine kinase inhibitors and immune checkpoint inhibitors-induced thyroid disorders Recently, tyrosine kinase inhibitors (TKI) and immune checkpoint inhibitors (ICPIs) have emerged as new classes of anticancer therapies. Although generally... tyrosine kinase inhibitors immune checkpoint induced thyroid disorders https://adisinsight.springer.com/trials/700350925?error=cookies_not_supported&code=d59e0c56-9586-48dd-9f32-fcf5b94292d0 A comparison of clinical effectiveness of immune checkpoint inhibitors in patients with stage III... This study aims to investigate the clinical outcomes of immune checkpoint inhibitors in patients with stage III and IV AM and compare them to cutaneous melanoma immune checkpoint inhibitors https://pmc.ncbi.nlm.nih.gov/articles/PMC9714419/ Highlights on Ocular Toxicity of Immune Checkpoint Inhibitors at a US Tertiary Cancer Center - PMC Immune checkpoint inhibitors (ICIs) have improved prognosis in advanced malignancies; however, they may be associated with extensive ocular immune-related... https://pubmed.ncbi.nlm.nih.gov/33653800/ LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across... immune checkpoint inhibitors associated with https://adisinsight.springer.com/drugsafety/803911625?error=cookies_not_supported&code=da048cb1-afa7-4dca-a9dc-809c7aef4b15 Immune checkpoint protein inhibitors - AdisInsight A group of 13 elderly patients (median age 67, mostly male) with advanced non-small cell lung cancer and acquired immune resistance developed adverse drug immune checkpoint protein inhibitors adisinsight https://experts.arizona.edu/en/publications/tumor-microenvironment-changes-leading-to-resistance-of-immune-ch/ Tumor microenvironment changes leading to resistance of immune checkpoint inhibitors in metastatic... immune checkpoint inhibitors tumor microenvironment https://adisinsight.springer.com/drugsafety/803928037?error=cookies_not_supported&code=65a71e57-9e90-4d98-bf48-c3aed45304d4 Immune checkpoint protein inhibitors - AdisInsight Forty-nine patients [ages and sexes not stated] treated with immune checkpoint inhibitors [dose, route, treatment duration and timing of onset not stated] immune checkpoint protein inhibitors adisinsight https://pubmed.ncbi.nlm.nih.gov/32683991/ Emerging drugs for small cell lung cancer: a focused review on immune checkpoint inhibitors Despite solid biological rationale, the results of clinical trials of ICIs in SCLC have yielded modest benefits. A small subset of patients does achieve... small cell lung cancer https://adisinsight.springer.com/drugsafety/803927429?error=cookies_not_supported&code=d1019490-b934-4e7c-90f8-62bacbcd0bb1 Immune checkpoint protein inhibitors - AdisInsight Twenty-two adults [ages and sexes not stated] treated with immune checkpoint inhibitors experienced biopsy-confirmed oesophagitis, and one of these patients immune checkpoint protein inhibitors adisinsight https://researchconnect.buffalo.edu/en/publications/predicting-response-to-checkpoint-inhibitors-in-melanoma-beyond-p/ Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden - SUNY... https://adisinsight.springer.com/drugsafety/803927320?error=cookies_not_supported&code=c8039cb5-808f-4519-ad70-43c8ad671fa6 Immune checkpoint protein inhibitors - AdisInsight A 77-year-old man with sarcomatoid malignant pleural mesothelioma received long-term immune checkpoint inhibitors [dose, route and treatment duration not immune checkpoint protein inhibitors adisinsight https://pubmed.ncbi.nlm.nih.gov/28923212/ A molecular and preclinical comparison of the PD-1-targeted T-cell checkpoint inhibitors nivolumab... T-cell checkpoint inhibition has a profound impact on cancer care and the programmed cell death protein 1 (PD-1)-targeted antibodies nivolumab and... https://pubmed.ncbi.nlm.nih.gov/31058078/ Chemotherapy in Combination With Immune Checkpoint Inhibitors for the First-Line Treatment of... immune checkpoint inhibitors https://boris-portal.unibe.ch/entities/publication/15af75f9-c84d-4ded-a822-5ed4bd8ce1a2 Treatment Patterns and Use of Immune Checkpoint Inhibitors Among Patients with Metastatic Bladder... Since 2017, two immune checkpoint inhibitors (ICIs) have become the standard of care for the treatment of metastatic urothelial carcinoma in Europe:... immune checkpoint inhibitors https://adisinsight.springer.com/drugsafety/803927249?error=cookies_not_supported&code=c99a457a-62a8-4951-b7ff-8bdf53823f7b Immune checkpoint protein inhibitors - AdisInsight Fifty-eight patients [age and sex not stated] who received immune checkpoint inhibitor therapy experienced immune checkpoint inhibitor-induced immune checkpoint protein inhibitors adisinsight https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.667875/full Frontiers | TNF-Alpha Pathway Alternation Predicts Survival of Immune Checkpoint Inhibitors in... Translational research on immune checkpoint inhibitors (ICIs) has been underway. However, in the unselected population, only a few patients benefit from ICIs... immune checkpoint inhibitors https://adisinsight.springer.com/drugsafety/803927534?error=cookies_not_supported&code=5e23d387-0dab-49ef-a782-d0de21675db4 Immune checkpoint protein inhibitors - AdisInsight Thirty-four adults (median age 59 years, 88.2% male) receiving immune checkpoint inhibitors at a single centre between 2019 and 2025 experienced bullous immune checkpoint protein inhibitors adisinsight https://pubmed.ncbi.nlm.nih.gov/34704214/ Efficacy and safety of immune checkpoint inhibitors in elderly patients with metastatic renal cell... The efficacy and safety of nivolumab monotherapy and nivolumab plus ipilimumab were comparable between elderly and young patients. Thus, chronological age... efficacy and safety https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1487227/full Frontiers | Case report: Long-term response to a combination of immune checkpoint inhibitors as a... IntroductionImmune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by enhancing the antitumor immune response. This case describes an 80-year... https://adisinsight.springer.com/drugsafety/803924085?error=cookies_not_supported&code=bc9fb2a8-4fc0-482e-9e19-d532508c3dda Immune checkpoint protein inhibitors - AdisInsight An 82-year-old man with stage 3 melanoma and pulmonary metastases developed myocarditis, myositis and myasthenic crisis (triple M syndrome) due to treatment immune checkpoint protein inhibitors adisinsight https://bibliographie.uni-tuebingen.de/xmlui/handle/10900/68697 Inflammation and Cancer: What Can We Therapeutically Expect from Checkpoint Inhibitors? can we inflammation cancer https://www.mdpi.com/2072-6694/12/3/738 Review of Indications of FDA-Approved Immune Checkpoint Inhibitors per NCCN Guidelines with the... Cancer is associated with higher morbidity and mortality and is the second leading cause of death in the US. Further, in some nations, cancer has overtaken... immune checkpoint inhibitors https://adisinsight.springer.com/drugsafety/803928181?error=cookies_not_supported&code=5772ef7a-ef63-41bf-afa9-b94bf346678c Immune checkpoint protein inhibitors/Programmed cell death 1 receptor antagonists - AdisInsight Fifty-nine adult patients [exact ages and sexes not stated] with cancer who received immune checkpoint inhibitors [dose, route and treatment duration not immune checkpoint cell death receptor antagonists protein inhibitors https://adisinsight.springer.com/drugsafety/803928904?error=cookies_not_supported&code=0e301b4a-b925-4038-ae21-893700bc77c6 Immune checkpoint protein inhibitors - AdisInsight A 79-year-old man with metastatic renal cell carcinoma received immune checkpoint inhibitors [route, dose and treatment duration not stated] and experienced immune checkpoint protein inhibitors adisinsight https://adisinsight.springer.com/drugsafety/803927554?error=cookies_not_supported&code=f184a01b-9588-49c4-8314-09eb08c3a8da Immune checkpoint protein inhibitors - AdisInsight Five patients [ages and sexes not stated] receiving immune checkpoint inhibitor therapy experienced acute interstitial nephritis with acute kidney injury [onset immune checkpoint protein inhibitors adisinsight https://pubmed.ncbi.nlm.nih.gov/31817109/ The Interplay between Inflammation, Anti-Angiogenic Agents, and Immune Checkpoint Inhibitors:... Treatment options for metastatic renal cell carcinoma (RCC) have been expanding in the last years, from the consolidation of several anti-angiogenic agents to... immune checkpoint interplay inflammation anti https://adisinsight.springer.com/drugsafety/803928183?error=cookies_not_supported&code=79d3efee-574a-41f1-8a02-29478f1d548a Immune checkpoint protein inhibitors - AdisInsight A total of 246 patients with cancer were treated with immune checkpoint inhibitors and experienced immune-related adverse events during the three-year period immune checkpoint protein inhibitors adisinsight https://adisinsight.springer.com/drugsafety/803927953?error=cookies_not_supported&code=515b7305-c2d3-4920-b7c0-2cfe2454ed17 Immune checkpoint protein inhibitors - AdisInsight Patients with gastric cancer [age and sex not stated] undergoing radical gastrectomy who received neoadjuvant immune checkpoint inhibitors experienced endocrine immune checkpoint protein inhibitors adisinsight https://adisinsight.springer.com/drugsafety/803928661?error=cookies_not_supported&code=55c223f8-5c20-45a0-979e-c4ccf97fd305 Immune checkpoint protein inhibitors - AdisInsight Ninety-six patients [age and sex not stated] with cancer at St Jamess Hospital received immune checkpoint inhibitors (ICIs) [dose, route and duration not immune checkpoint protein inhibitors adisinsight https://pubmed.ncbi.nlm.nih.gov/32211263/?dopt=Abstract Initial Experience after Transition to Immune Checkpoint Inhibitors in Patients with Non-small Cell... Objective The aim of this study was to investigate the patterns of palliative care, terminal care, and hospital deaths in deceased patients with non-small cell... https://publikationen.uni-tuebingen.de/xmlui/handle/10900/140997 Biomarkers Associated with Immune-Related Adverse Events under Checkpoint Inhibitors in Metastatic... associated with adverse events https://pubmed.ncbi.nlm.nih.gov/30715219/ Cardiovascular toxicities associated with immune checkpoint inhibitors Cardiovascular toxicities associated with immune checkpoint inhibitors (ICIs) have been reported in case series but have been underappreciated due to their... associated with immune checkpoint cardiovascular inhibitors https://pubmed.ncbi.nlm.nih.gov/40438876/ Efficacy and safety of BCG and immune checkpoint inhibitors in non-muscle invasive bladder cancer:... Bladder cancer (BC) is a significant global health concern and includes non-muscle-invasive BC (NMIBC), which poses challenges due to recurrence and... efficacy and safety https://pubmed.ncbi.nlm.nih.gov/32212881/ Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors about covid immune checkpoint controversies https://pubmed.ncbi.nlm.nih.gov/39696266/ Efficacy, safety, and biomarker analysis of first-line immune checkpoint inhibitors with... Adding ICIs to first-line treatment significantly prolongs survival in overall patients and in those with PD-L1 CPS 1-4 or unknown. This study also provides... immune checkpoint inhibitors biomarker analysis https://adisinsight.springer.com/drugsafety/803928886?error=cookies_not_supported&code=a460aa5f-8eb1-4b04-bd90-406d83c9a505 Immune checkpoint protein inhibitors - AdisInsight Two hundred and ninety-eight patients [age and sex not stated] with cancer received an immune checkpoint inhibitor [dose, route, duration and time to onset not immune checkpoint protein inhibitors adisinsight https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1611036/full Frontiers | Advances in radiotherapy enhancing the efficacy of immune checkpoint inhibitors in... The introduction of immune checkpoint inhibitors (ICIs) has facilitated the elucidation of the mechanisms underlying the remote effects observed in tumor the... immune checkpoint frontiers advances radiotherapy enhancing https://pubmed.ncbi.nlm.nih.gov/34277306/ Myasthenia Gravis as an Immune-Mediated Side Effect of Checkpoint Inhibitors This is a case report of new-onset myasthenia gravis (MG) as an immune-mediated adverse event (irAE) related to the use of pembrolizumab in a patient with... myasthenia gravis side effect immune https://pubchem.ncbi.nlm.nih.gov/bioassay/1963452 AID 1963452 - qHTS drug screen for cell cycle checkpoint inhibitors in PARPi-resistant BRCA-mutant... BioAssay record AID 1963452 submitted by National Center for Advancing Translational Sciences (NCATS): qHTS drug screen for cell cycle checkpoint inhibitors in... https://dimec.unibo.it/it/ricerca/esplora-la-ricerca/progetti-da-finanziamenti-nazionali/ruolo-di-cd44-nei-meccanismi-di-resistenza-al-trattamento-con-immune-checkpoint-inhibitors-ici-del-carcinoma-polmonare-non-a-piccole-celule-nsclc Ruolo di CD44 nei meccanismi di resistenza al trattamento con immune checkpoint inhibitors (ICI)... Responsabile scientifico: prof. Lollini Pier Luigi https://pmc.ncbi.nlm.nih.gov/articles/PMC11267150/ The evolving role of immune checkpoint inhibitors in cervical and endometrial cancer - PMC The introduction of immune checkpoint inhibitors (ICIs) has revolutionized the treatment landscape for numerous tumor types, including cervical and endometrial... immune checkpoint inhibitors