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https://www.broadinstitute.org/news/gene-editing-extends-lifespan-mouse-model-prion-disease Gene editing extends lifespan in mouse model of prion disease | Broad Institute A single-letter edit in DNA reduces levels of the disease-causing prion protein in the brain and could lead to a preventative, one-time treatment for the... disease broad institute gene editing mouse model extends lifespan https://www.broadinstitute.org/publications/broad1364001 Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease. | Broad Institute rare genetic disease patient specific broad institute vivo editing https://www.broadinstitute.org/nnfc Novo Nordisk Foundation Center for Genomic Mechanisms of Disease | Broad Institute novo nordisk foundation disease broad institute center genomic mechanisms https://www.broadinstitute.org/kidney-disease Kidney disease | Broad Institute We work in close partnership with the Broad’s Center for the Development of Therapeutics (CDoT) and several Broad platforms (Genomics, Proteomics, Genetic... kidney disease broad institute https://www.broadinstitute.org/medical-and-population-genetics/rare-disease Rare disease | Broad Institute In addition to studying common, complex disease, scientists in the program focus on rare diseases, including muscle disorders, mitochondrial disorders, and... disease broad institute rare https://www.broadinstitute.org/nnfc/job-opportunities Job Opportunities in the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease | Broad... novo nordisk foundation job opportunities disease broad center genomic https://www.broadinstitute.org/news/approach-studies-how-rare-gene-variant-pairs-contribute-disease Approach studies how rare gene variant pairs contribute to disease | Broad Institute Strategy infers whether variants that appear in the same gene are on the same copy of that gene, could improve genetic diagnosis of disease disease broad institute gene variant approach studies rare https://www.broadinstitute.org/news/genetic-predisposition-unveiled-diabetic-kidney-disease Genetic predisposition unveiled in diabetic kidney disease | Broad Institute Broad Institute is a multidisciplinary community of researchers on a mission to improve human health. kidney disease broad genetic predisposition unveiled diabetic https://www.broadinstitute.org/cardiovascular-disease Cardiovascular disease | Broad Institute The CVDi, led by Patrick Ellinor, aims to reduce the burden of cardiovascular disease and sudden cardiac death through four goals: disease broad institute cardiovascular https://www.broadinstitute.org/carlos-slim-center-health-research/kidney-disease Kidney Disease | Broad Institute kidney disease broad institute https://www.broadinstitute.org/medical-and-population-genetics/metabolic-disease Metabolic disease | Broad Institute The genetic basis of diseases associated with hormonal imbalance is being investigated. These include diabetes, obesity, and cardiovascular traits, in... disease broad institute metabolic https://www.broadinstitute.org/news/scientists-create-next-generation-tools-battle-against-brain-disease Scientists create next generation of tools in battle against brain disease | Broad Institute The findings contained in eight studies could lead to targeted gene therapies for brain disorders. create next generation disease broad institute scientists tools battle https://www.broadinstitute.org/rare-disease Rare disease | Broad Institute Broad scientists employ a variety of approaches, including DNA and RNA sequencing, to identify genetic variants that give rise to rare disease. They also study... disease broad institute rare https://www.broadinstitute.org/news/genetic-base-editing-treats-sickle-cell-disease-mice Genetic base editing treats sickle cell disease in mice | Broad Institute Broad Institute is a multidisciplinary community of researchers on a mission to improve human health. sickle cell disease base editing broad institute genetic treats https://www.broadinstitute.org/news/organoids-emerge-powerful-tools-disease-modeling-and-drug-discovery Organoids emerge as powerful tools for disease modeling and drug discovery | Broad Institute Broad Institute is a multidisciplinary community of researchers on a mission to improve human health. discovery broad institute powerful tools disease modeling organoids emerge https://www.broadinstitute.org/disease-areas Disease areas | Broad Institute Our community seeks to translate genetic, mechanistic, and cellular discoveries into deep biological knowledge of the roots of common and rare human diseases,... disease areas broad institute https://www.broadinstitute.org/news/scientists-link-certain-gut-bacteria-lower-heart-disease-risk Scientists link certain gut bacteria to lower heart disease risk | Broad Institute Study finds several species of cholesterol-metabolizing bacteria in people with lower cholesterol levels. heart disease risk gut bacteria broad institute scientists certain https://www.broadinstitute.org/infectious-disease-microbiome Infectious disease and microbiome | Broad Institute Scientists at the Broad share ideas and launch collaborative projects to tackle key challenges. The IDM program includes collaborations across several Broad... infectious disease broad institute microbiome https://www.broadinstitute.org/news/clinical-genomicist-harnesses-team-based-science-help-rare-disease-patients A clinical genomicist harnesses team-based science to help rare-disease patients | Broad Institute Heidi Rehm convinced labs and scientists to work together and share data. This has helped many people with rare disease find answers. rare disease patients team based broad institute clinical harnesses https://www.broadinstitute.org/news/potential-alzheimers-disease-therapeutic-target-identified-brain-immune-cells Potential Alzheimer’s disease therapeutic target identified in brain immune cells | Broad Institute Scientists discover possible way to harness immune cells in the brain to remove plaques associated with Alzheimer's. cells broad institute therapeutic target brain immune potential disease https://www.broadinstitute.org/rare-diseases/muc1-kidney-disease-mkd MUC1 kidney disease (MKD) | Broad Institute kidney disease broad institute mkd