Robuta

241242 Fab heavy chain241242 Fab light chainReticulocyte binding protein 2b

Protein phosphorylation and dephosphorylation (catalysed by kinases and phosphatases, respectively) are post-translational modifications that play key roles in...

Glutathione S-transferaseCHLORIDE IONGLUTATHIONE

The clinical trial showed that quinine 3-days combined to SP is still relatively effective in the Chittagong Hill Tracts. However, if this regimen is continued...

Plasmodium falciparum M1 aminopeptidase bound to selective inhibitor MIPS2673

Farnesyl pyrophosphate synthase3-(2,2-diphosphonoethyl)-1-dodecyl-1H-imidazol-3-iumMAGNESIUM IONSULFATE ION

The recent identification of antisense RNA in the transcriptomes of many eukaryotes has generated enormous interest. The presence of antisense RNA in...

Crystal Structure of the GMP Synthetase from Plasmodium falciparum

A major tool against malaria in Africa has been the use of rapid diagnostic tests, which have been part of the 'test-treat-track' strategy in Ethiopia, the...

Dihydroorotate dehydrogenase (quinone), mitochondrialFLAVIN MONONUCLEOTIDEOROTIC ACIDethyl...

7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthaseACETATE IONADENOSINE-5'-TRIPHOSPHATECALCIUM IONGLYCEROLMAGNESIUM...

Passive transfer studies in humans clearly demonstrated the protective role of IgG antibodies against malaria. Identifying the precise parasite antigens that...

Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1251

DNA (32-MER)L-lactate dehydrogenaseMAGNESIUM ION

The apicoplast gyrases differ significantly from bacterial gyrases while retaining similar core domains. T. gondii Gyrase B may have an unusual or inefficient...

Crystal Structure of Plasmodium falciparum actin I (H74Q) in the Mg-K-ATP state

GLUTAMATE DEHYDROGENASE (NADP+)

Glycylpeptide N-tetradecanoyltransferase5-(4-chlorophenyl)-3-({[3-(morpholine-4-carbonyl)phenyl]amino}methyl)pyridin-2(1H)-oneBETA-MERCAPTOETHANOLCHLORIDE...

Regulatory milestone affirms GSK's strong commitment and scientific capabilities to fighting infectious diseases

Variation in the immunodominant T cell epitopes Th2R and Th3R of the Plasmodium falciparum circumsporozoite protein has been analysed from Gambian clinical...

The coordinated exit of intracellular pathogens from host cells is a process critical to the success and spread of an infection. While phospholipases have been...

Plasmodium falciparum is the parasite responsible for malaria. It uses phosphosignaling to infect host cells and propagate.

Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine

The human parasite Plasmodium falciparum has the potential to express a vast repertoire of variant proteins on the surface of the infected red blood cell...

Recombinant vaccinia viruses (rVV) are effective antigen delivery vectors and are researched widely as vaccine platforms against numerous diseases. Apical...

Multi-omic analyses reveal that the chromatin-associated microrchidia protein, MORC (PF3D7_1468100), at the blood stage of the human malaria parasite,...

Enoyl-ACP reductase2-(2-amino-4-chlorophenoxy)-5-chlorophenolNICOTINAMIDE-ADENINE-DINUCLEOTIDE