https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00260/full
Frontiers | Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity...
Triptolide (TP), a diterpenoid isolated from Tripterygium wilfordii Hook F, has an excellent pharmacological profile of immunosuppression and anti-tumor acti...
signaling pathwayfrontiersactivationsirt1fxr
https://www.thermofisher.com/antibody/product/SIRT1-Antibody-Polyclonal/PA5-23063
SIRT1 Polyclonal Antibody | Invitrogen (PA5-23063)
Detect SIRT1 in WB, ICC/IF, IHC (P), ELISA, IP. Reacts with Rabbit, Mouse, Goat, Chicken, Sheep. Cited in 1 publication. Catalog # PA5-23063
polyclonal antibodysirt1invitrogenpa523063
https://elifesciences.org/reviewed-preprints/93125
Salmonella-induced SIRT1 and SIRT3 are crucial for maintaining the metabolic switch in bacteria and...
https://www.jci.org/assets/260671/powerpoint
JCI - The role of Sirt1 in renal rejuvenation and resistance to stress
the role
https://elifesciences.org/articles/70672
The hepatic AMPK-TET1-SIRT1 axis regulates glucose homeostasis | eLife
A series of experiments at the molecular level reveal the underlying mechanism of how a gene activates liver glucose production to regulate the blood glucose...
glucose homeostasishepaticampktet1sirt1
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2020.568861/full
Frontiers | SIRT1 Antagonizes Oxidative Stress in Diabetic Vascular Complication
Diabetic mellitus (DM) is a significant public health concern worldwide with an increased incidence of morbidity and mortality, which is particularly due to ...
oxidative stressfrontierssirt1diabeticvascular
https://www.thermofisher.com/antibody/product/SIRT1-Antibody-Polyclonal/PA5-20964
SIRT1 Polyclonal Antibody | Invitrogen (PA5-20964)
Detect SIRT1 in WB, ICC/IF, IHC (P), ELISA, IP. Reacts with Rabbit, Mouse, Goat, Chicken, Sheep. Cited in 3 publications. Catalog # PA5-20964
polyclonal antibodysirt1invitrogenpa520964
https://elifesciences.org/articles/55828v1/figures
Figures and data in Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the...
https://stanforddaily.com/tag/sirt1/
Articles about SIRT1 - The Stanford Daily
the stanfordarticlessirt1daily
https://www.spandidos-publications.com/10.3892/mmr.2025.13603/abstract
[Retracted] SIRT1 activation by resveratrol reduces brain edema and neuronal apoptosis in an...
Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9370141/
Ketone Bodies and SIRT1, Synergic Epigenetic Regulators for Metabolic Health: A Narrative Review -...
Ketone bodies (KBs) and Sirtuin-1 (SIRT1) have received increasing attention over the past two decades given their pivotal function in a variety of biological...
https://www.spandidos-publications.com/10.3892/mmr.2024.13192
[Retracted] Liraglutide repairs the infarcted heart: The role of the SIRT1/Parkin/mitophagy pathway
Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.
https://www.rcsb.org/structure/4ZZJ
RCSB PDB - 4ZZJ: SIRT1/Activator/Substrate Complex
SIRT1/Activator/Substrate Complex
rcsb pdbsirt1 activatorsubstratecomplex
https://elifesciences.org/articles/55828/peer-reviews
Peer review in Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA...
SIRT1 deacetylates SIRT6 at K33 to facilitate DNA double-strand breaks-recognition, subsequent expansion and local chromatin remodeling.
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.785403/full
Frontiers | Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and...
Background and purpose: FXR is a promising target for the treatment of human cholestatic liver disease (CLD). SIRT1 is a deacetylase which promotes FXR activ...
frontierspterostilbenecholestasis
https://www.jax.org/strain/038608
038608 - Sirt1[cKI-H355A] Strain Details
sirt1ckistraindetails
https://www.spandidos-publications.com/10.3892/ijmm.16.2.237
SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress
International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11229984/
Inflammation Can Be a High-Risk Factor for Mucosal Nonunion of MRONJ by Regulating SIRT1 Signaling...
Zoledronate (ZA) stands as a highly effective antiresorptive agent known to trigger medication-related osteonecrosis of the jaw (MRONJ). Its clinical dosages...
https://www.miragenews.com/hepatic-sirt1-from-metabolism-to-immune-therapy-1570054/
Hepatic SIRT1: From Metabolism to Immune Therapy | Mirage News
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disorder globally, with a rising
immune therapyhepaticsirt1metabolismmirage
https://www.jax.org/strain/029603
029603 - Sirt1[loxP] Strain Details
sirt1loxpstraindetails
https://www.thermofisher.com/antibody/product/SIRT1-Antibody-clone-OTI1H1-Monoclonal/MA5-27216
SIRT1 Monoclonal Antibody (OTI1H1) | Invitrogen (MA5-27216)
Detect SIRT1 in WB, ICC/IF, IHC (P), ELISA, IP. Reacts with Rabbit, Mouse, Goat, Chicken, Sheep. Catalog # MA5-27216
monoclonal antibodysirt1invitrogenma5
https://www.thermofisher.com/antibody/product/SIRT1-Antibody-clone-2F11-Recombinant-Monoclonal/82790-4-RR
SIRT1 Recombinant Rabbit Monoclonal Antibody (2F11) | Invitrogen (82790-4-RR)
Detect SIRT1 in WB, ICC/IF, IHC (P), ELISA, IP. Reacts with Rabbit, Mouse, Goat, Chicken, Sheep. Catalog # 82790-4-RR
rabbit monoclonalsirt1recombinantantibodyinvitrogen
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2023.1121982/full
Frontiers | Interaction between SIRT1 and non-coding RNAs in different disorders
SIRT1 is a member of the sirtuin family functioning in the process of removal of acetyl groups from different proteins. This protein has several biological f...
non coding rnasfrontiersinteractionsirt1
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.930919/full
Frontiers | SIRT1 and Autophagy: Implications in Endocrine Disorders
Autophagy is a cellular process involved in the selective degradation and recycling of dysfunctional intracellular components. It plays a crucial role in mai...
frontierssirt1autophagyimplicationsendocrine
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1514745/full
Frontiers | SIRT1: potential target in glucocorticoid-resistant diseases
Glucocorticoid resistance is a challenging problem in clinical practice. Increasing glucocorticoid sensitivity and reducing resistance are important in the m...
frontierssirt1potentialtargetglucocorticoid
https://pmc.ncbi.nlm.nih.gov/articles/PMC3527007/
SIRT1 and energy metabolism - PMC
Sirtuin 1 (SIRT1) is the most conserved mammalian NAD+-dependent protein deacetylase that has emerged as a key metabolic sensor in various metabolic tissues....
energy metabolismsirt1pmc
https://www.thermofisher.com/antibody/product/Phospho-SIRT1-Ser47-Antibody-clone-5F5-Recombinant-Monoclonal/MA572031
Phospho-SIRT1 (Ser47) Recombinant Rabbit Monoclonal Antibody (5F5) (MA572031)
Detect Phospho-SIRT1 (Ser47) in WB, ICC/IF, IHC (P), Flow, ELISA. Reacts with Rabbit. Catalog # MA572031
rabbit monoclonalphosphosirt1recombinantantibody
https://www.jci.org/articles/view/41563
JCI - Sirt1 activation protects the mouse renal medulla from oxidative injury
the mouserenal medullajcisirt1activation
https://pmc.ncbi.nlm.nih.gov/articles/PMC3616265/
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal...
During fasting and after exercise, skeletal muscle efficiently switches from carbohydrate to lipid as the main energy source to preserve glycogen stores and...
https://www.spandidos-publications.com/10.3892/ijmm.2019.4106/abstract
SIRT1 inhibits apoptosis in in vivo and in vitro models of spinal cord injury via microRNA-494
International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
https://www.sigmaaldrich.com/US/en/product/sigma/av32386
SIRT1 antibody Western AV32386
Anti-SIRT1 antibody produced in rabbit affinity isolated antibody; Synonyms: Anti-Sirtuin (silent mating type information Regulation 2 homolog) 1 (S....
sirt1antibodywestern
https://pmc.ncbi.nlm.nih.gov/articles/PMC6090043/
Inverse Association of Circulating SIRT1 and Adiposity: A Study on Underweight, Normal Weight, and...
Context: Sirtuins (SIRTs) are NAD+-dependent deacetylases, cellular sensors to detect energy availability, and modulate metabolic processes. SIRT1, the most...
https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2022.943842/full
Frontiers | SIRT1 activation attenuates microglia-mediated synaptic engulfment in postoperative...
Background: Postoperative cognitive dysfunction (POCD) is a debilitating neurological complication in surgical patients. Current research has focused mainly ...
frontierssirt1activationmicrogliamediated