ubiquitin ligase - Robuta Search

https://www.spandidos-publications.com/10.3892/or.2016.4605/abstract Cullin-5, a ubiquitin ligase scaffold protein, is significantly underexpressed in endometrial... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. 5 a ubiquitin ligase scaffold protein https://elifesciences.org/reviewed-preprints/88466v1 E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless... e3 ubiquitin ligase https://www.scirp.org/journal/articles?searchcode=COP9+Signalosome%3B+CHOP%3B+Adipogenesis%3B+Cullin-RING+Ubiquitin+Ligase&searchfield=keyword&page=1 COP9 Signalosome; CHOP; Adipogenesis; Cullin-RING Ubiquitin Ligase - Articles - Scientific Research... COP9 Signalosome; CHOP; Adipogenesis; Cullin-RING Ubiquitin Ligase cop9 signalosome ubiquitin ligase chop adipogenesis cullin https://www.wikidata.org/wiki/Q55060421 The protein substrate binding site of the ubiquitin-protein ligase system - Wikidata binding site ubiquitin ligase protein substrate system https://www.jci.org/articles/view/92069 JCI - Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia in the ubiquitin ligase jci mutations https://www.frontiersin.org/journals/neuroscience/articles/10.3389/neuro.01.004.2009/full Frontiers | KF-1 ubiquitin ligase: an anxiety suppressor Anxiety is an instinct that may have developed to promote adaptive survival by evading unnecessary danger. However, excessive anxiety is disruptive and can b... ubiquitin ligase frontiers kf 1 anxiety https://www.semanticscholar.org/topic/SCF-ubiquitin-ligase-complex/604096 SCF ubiquitin ligase complex | Semantic Scholar A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a... scf ubiquitin ligase complex semantic scholar https://www.ncbi.nlm.nih.gov/protein/5FG1_A Chain A, E3 ubiquitin-protein ligase listerin - Protein - NCBI ubiquitin protein ligase chain e3 ncbi https://www.ncbi.nlm.nih.gov/protein/8IKT_A Chain A, E3 ubiquitin-protein ligase parkin - Protein - NCBI ubiquitin protein ligase chain e3 parkin ncbi https://www.mdpi.com/1422-0067/21/22/8719 E3 Ubiquitin Ligase APC/CCdh1 Negatively Regulates FAH Protein Stability by Promoting Its... Fumarylacetoacetate hydrolase (FAH) is the last enzyme in the degradation pathway of the amino acids tyrosine and phenylalanine in mammals that catalyzes the... e3 ubiquitin ligase https://elifesciences.org/articles/13841v1 A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at... https://elifesciences.org/articles/85727 A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage... The Dictyostelium discoideum TRAF6 homolog TrafE coordinates the autophagy and ESCRT membrane repair machineries and works in the major cell-autonomous... https://elifesciences.org/articles/00459/figures Figures and data in The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality... Ubiquitin ligase adaptors target the selective clearance of misfolded plasma membrane proteins. https://www.ncbi.nlm.nih.gov/gene/1184744 hopAB2 type III secretion system effector E3 ubiquitin-protein ligase HopAB2 [Pseudomonas syringae... type iii secretion system ubiquitin protein ligase https://elifesciences.org/articles/07217 Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1... Orphan nuclear receptor Nur77 protects bone by enabling a timely termination of osteoclast differentiation. https://elifesciences.org/articles/92757/peer-reviews Peer review in Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase... Commissureless works with the Nedd4 E3 ubiquitin ligase to transiently degrade the Robo1 receptor to allow commissural axons to cross the midline. https://www.wikidata.org/wiki/Q68268502 Specificity of binding of NH2-terminal residue of proteins to ubiquitin-protein ligase. Use of... scientific article published on 01 February 1988 ubiquitin protein ligase nh2 terminal https://www.jci.org/articles/view/68996/figure/3 JCI - Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain voltage gated sodium channels https://elifesciences.org/articles/71928v1/figures Figures and data in The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent... https://www.spandidos-publications.com/10.3892/or.2014.3695/abstract Ubiquitin ligase Siah1 promotes the migration and invasion of human glioma cells by regulating... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. https://www.ncbi.nlm.nih.gov/protein/2L3R_A Chain A, E3 ubiquitin-protein ligase UHRF1 - Protein - NCBI ubiquitin protein ligase chain e3 uhrf1 ncbi https://elifesciences.org/articles/71928v1/peer-reviews Peer review in The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent... https://www.ncbi.nlm.nih.gov/protein/8G7V_D Chain D, E3 ubiquitin-protein ligase RNF135 - Protein - NCBI ubiquitin protein ligase chain e3 rnf135 ncbi https://www.ncbi.nlm.nih.gov/protein/5HMK_A Chain A, E3 ubiquitin-protein ligase Mdm2 - Protein - NCBI ubiquitin protein ligase chain e3 mdm2 ncbi https://www.rcsb.org/structure/4CI3 RCSB PDB - 4CI3: Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide https://www.wikidata.org/wiki/Q70870874 Isolation, characterization, and partial purification of a novel ubiquitin-protein ligase, E3.... scientific article published on 01 January 1996 ubiquitin protein ligase https://www.wikidata.org/wiki/Q24291032 Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the... https://elifesciences.org/articles/00459/peer-reviews Peer review in The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control... Ubiquitin ligase adaptors target the selective clearance of misfolded plasma membrane proteins. https://www.ncbi.nlm.nih.gov/gene?term=494470 ARK2C arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C [Homo sapiens (human)] -... https://www.jci.org/articles/view/140615 JCI - Gain-of-function mutation in ubiquitin ligase KLHL24 causes desmin degradation and dilatation... gain of function mutation https://www.rcsb.org/structure/6TTU RCSB PDB - 6TTU: Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution:... Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2 https://www.rcsb.org/structure/8ROY RCSB PDB - 8ROY: Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to compound... Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to compound furan 24 https://www.ncbi.nlm.nih.gov/gene/9870 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 [Homo sapiens (human)] - Gene - NCBI ubiquitin protein ligase https://www.rcsb.org/structure/3LRQ RCSB PDB - 3LRQ: Crystal structure of the U-box domain of human ubiquitin-protein ligase (E3),... Crystal structure of the U-box domain of human ubiquitin-protein ligase (E3), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4604D. https://www.ncbi.nlm.nih.gov/gene/51514 DTL denticleless E3 ubiquitin protein ligase adapter [Homo sapiens (human)] - Gene - NCBI ubiquitin protein ligase https://www.wikidata.org/wiki/Q24290777 Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for... https://www.rcsb.org/structure/5LP8 RCSB PDB - 5LP8: Crystal structure of an asymmetric dimer of the ubiquitin ligase HUWE1 Crystal structure of an asymmetric dimer of the ubiquitin ligase HUWE1 https://www.wikidata.org/wiki/Q28138489 A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling... scientific article (publication date: March 1999) https://www.wikidata.org/wiki/Q24597101 The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53... https://www.wikidata.org/wiki/Q39754053 The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus... https://www.ncbi.nlm.nih.gov/protein/6VFO_A Chain A, E3 ubiquitin-protein ligase UHRF1 - Protein - NCBI ubiquitin protein ligase chain e3 uhrf1 ncbi https://www.muni.cz/vyzkum/publikace/1721436 Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled |... https://www.wikidata.org/wiki/Q28116145 Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to... ubiquitin protein ligase https://www.universiteitleiden.nl/en/events/2025/06/lsb2-seminar-sonja-lorenz L(SB)2 Seminar: Conformational regulation of the GTPase-interacting ubiquitin ligase HACE1 - Leiden... The ubiquitin system is a principal regulator of cellular signaling in eukaryotes, deregulation of which is linked to manifold diseases pathways. It is... https://www.rcsb.org/structure/4LJO RCSB PDB - 4LJO: Structure of an active ligase (HOIP)/ubiquitin transfer complex Structure of an active ligase (HOIP)/ubiquitin transfer complex rcsb pdb https://www.ncbi.nlm.nih.gov/protein/8SMW_K Chain K, E3 ubiquitin-protein ligase RNF168 - Protein - NCBI ubiquitin protein ligase chain k e3 ncbi https://pmc.ncbi.nlm.nih.gov/articles/PMC11880400/ E3 ubiquitin ligase RNF128 promotes Lys63-linked polyubiquitination on SRB1 in macrophages and... Macrophage-derived foam cell formation is the hallmark of atherosclerotic plaques prominently attributed to excessive lipid uptake and metabolic disorders. As... e3 ubiquitin ligase https://elifesciences.org/articles/44288 The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer... Targeting the CRL5 ubiquitin ligase complex in combination with CDK9 or MCL1 inhibition could combat innate and acquired resistance of cancer cells to... https://www.rcsb.org/structure/3L4H RCSB PDB - 3L4H: Helical box domain and second WW domain of the human E3 ubiquitin-protein ligase... Helical box domain and second WW domain of the human E3 ubiquitin-protein ligase HECW1 https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01926/full Frontiers | The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked... Innate immunity is the first-line defense against antiviral or antimicrobial infection. RIG-I and MDA5, which mediate the recognition of pathogen-derived nuc... https://www.jci.org/articles/view/32741/version/3 JCI - The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity https://elifesciences.org/articles/35528 The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the... Proteomic, biochemical and cell-based analyses of the heterodecameric core GID/CTLH E3 ligase complex reveal its molecular architecture, activity determinants,... e3 ubiquitin ligase https://www.spandidos-publications.com/ijmm/30/6/1281 RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid... International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease. https://www.wikidata.org/wiki/Q24297048 Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase - Wikidata https://www.wikidata.org/wiki/Q28201996 The Nedd8-conjugated ROC1-CUL1 Core Ubiquitin Ligase Utilizes Nedd8 Charged Surface Residues for... scientific article (publication date: 4 January 2002) https://www.jci.org/assets/293196/powerpoint JCI - Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain voltage gated sodium channels https://www.mdpi.com/1999-4915/15/5/1070 A Novel Recognition by the E3 Ubiquitin Ligase of HSV-1 ICP0 Enhances the Degradation of PML... Upon viral entry, components of ND10 nuclear bodies converge with incoming DNA to repress viral expression. The infected cell protein 0 (ICP0) of herpes... https://www.wikidata.org/wiki/Q59251306 E3 ubiquitin-protein ligase Rad18 - Wikidata ubiquitin protein ligase e3 rad18 wikidata