https://podcast.cfrc.ca/podcast/cancer-chaos-exploiting-dysfunctional-relationships-between-dna-chromatin-in-cancer-therapeutics/
Jun 13, 2024 - Get to know our special guest Dr. Lynne Postovit. Dr. Postovit earned her Bachelor of Science (Honours) at Queen’s University in 1999. After receiving her...
cancerchaosexploitingdysfunctionalrelationships
https://www.epigeneticslab-aiims.info/rashmi-gupta?lang=hi
Laboratory of Chromatin and Cancer Epigenetics indulging in opening the new avenues for novel Cancer Testis/Germline (CT/CG) POTE antigens to be used as...
cancer epigeneticsrashmiguptalaboratorychromatin
https://pubmed.ncbi.nlm.nih.gov/26679111/
Histone-modifying enzymes are required for cell identity and lineage commitment, however little is known about the regulatory origins of the epigenome during...
embryonictranscriptioncontrolleddefinedchromatin
https://www.peterbrazda.com/publication/brazda-2014-ligand/
Retinoid X receptor (RXR) is a promiscuous nuclear receptor forming heterodimers with several other receptors, which activate different sets of genes. Upon...
retinoid x receptorligand bindinghighlymobile
https://www.semanticscholar.org/topic/transcriptionally-active-chromatin/390500
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed. [GOC:sart, PMID:17965872]
semantic scholaractivechromatin
https://www.brainchromatindynamics.com/
This site introduces the Chromatin Neurobiology Lab / Iwase lab. We aim to discover novel chromatin-regulatory mechanisms in the brain. Neuroepigenetics.
united statesneuroepigeneticsiwaselabchromatin
https://pubmed.ncbi.nlm.nih.gov/17303193/
Current research is demonstrating that the packaging of the eukaryotic genome together with histone proteins into chromatin is playing a fundamental role in...
dna repairchromatindisassemblyreassembly
https://pubmed.ncbi.nlm.nih.gov/33214551/?dopt=Abstract
O-GlcNAc modification plays critical roles in regulating the stress response program and cellular homeostasis. However, systematic and multi-omics studies on...
proteomic profilinggenomewidemappingglcnac
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.732033/full
The majority of genetic variants for psychiatric disorders have been found within non-coding genomic regions. Physical interactions of gene promoters with di...
neurological diseasesfrontiersloopinterrupteddysfunctional
https://www.frontiersin.org/journals/epigenetics-and-epigenomics/articles/10.3389/freae.2024.1439973/full
Transcription is one of the central dogmas of life. Most genes in eukaryotes are transcribed by RNA polymerase II (Pol II). For Pol II to transcribe along th...
frontiershypotheticalmodelchromatincouple
https://pubmed.ncbi.nlm.nih.gov/24357409/
Our knowledge of the role of higher-order chromatin structures in transcription of microRNA genes (MIRs) is evolving rapidly. Here we investigate the effect of...
dissectingchromatininteractomemicrornagenes
https://pubmed.ncbi.nlm.nih.gov/39075073/
Gene expression is regulated by changes in chromatin architecture intrinsic to cellular differentiation and as an active response to environmental stimuli....
centuryoldchromatinarchitecturerevealed
https://pubmed.ncbi.nlm.nih.gov/15208625/
During skeletal myogenesis, genomic reprogramming toward terminal differentiation is achieved by recruiting chromatin-modifying enzymes to muscle-specific...
chromatin remodelingpathwaytargetsswisnf
https://pubmed.ncbi.nlm.nih.gov/32994332/
The genomes of DNA tumor viruses regain nuclear localization after nuclear envelope breakdown during mitosis through the action of a viral protein with a...
human cytomegalovirusgenomessurvivemitosisvia
https://pubmed.ncbi.nlm.nih.gov/32034718/?from_sort=date&from_term=Kaminska+B&from_cauthor_id=32034715&from_pos=5
Signal transduction pathways directly communicate and transform chromatin to change the epigenetic landscape and regulate gene expression. Chromatin acts as a...
histonemodifyingenzymeschromatinmodifiers
https://pubmed.ncbi.nlm.nih.gov/40087883/?dopt=Abstract
The SWI/SNF chromatin-remodeling complex that comprises multiple subunits orchestrates diverse cellular processes, including gene expression, DNA repair, and...
armadillodomaindirectlydnapkcs
https://pubmed.ncbi.nlm.nih.gov/35867248/
The introduction of chromosome conformation capture (3C)-based technologies coupled with next-generation sequencing have significantly advanced our...
specificnetworkschromatininteractions
https://www.ncbi.nlm.nih.gov/books/NBK9863/
Not only are the genomes of most eukaryotes much more complex than those of prokaryotes, but the DNA of eukaryotic cells is also organized differently from...
the cellncbi bookshelfchromosomeschromatin
https://pubmed.ncbi.nlm.nih.gov/30401455/
Understanding general principles that safeguard cellular identity should reveal critical insights into common mechanisms underlying specification of varied...
sumosafeguardssomaticpluripotentcell
https://pubmed.ncbi.nlm.nih.gov/35817982/
Mapping chromatin loops from noisy Hi-C heatmaps remains a major challenge. Here we present DeepLoop, which performs rigorous bias correction followed by...
mapschromatininteractionssparseallele
https://pubmed.ncbi.nlm.nih.gov/30078726/
Linking regulatory DNA elements to their target genes, which may be located hundreds of kilobases away, remains challenging. Here, we introduce Cicero, an...
single cellcicerocisregulatorydna
https://pubmed.ncbi.nlm.nih.gov/25425661/
DNA methylation in Arabidopsis thaliana is maintained by at least four different enzymes: DNA methyltransferase1 (MET1), chromomethylase3 (CMT3), domains...
chromatinremodelerfamilyproteinsrequired
https://ips2.u-psud.fr/en/articles/whole-genome-chromatin-landscape-of-medicago-truncatula-symbiotic-genes.html
Advances in deciphering the functional architecture of eukaryotic genomes have recently been facilitated by technological advances in sequencing techniques,...
medicago truncatulawholegenomechromatinlandscape
https://www.stjude.org/education-training/advanced-training/seminars-symposia/bringing-chemistry-to-medicine-symposium-transcription-therapy-cbt/videos/kidoch-2021-structure-and-function-of-mammalian.html
Listen to Cigall Kidoch, PhD speak on "Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer" from the 2021 Bringing...
chromatin remodelingstructurefunctionmammalianswi