Robuta

https://www.mdpi.com/1422-0067/23/14/7737
Despite initial responses to first-line treatment with platinum and taxane-based combination chemotherapy, most high-grade serous ovarian carcinoma (HGSOC)...
long noncoding rnaupregulationcisplatinresistance
https://pubmed.ncbi.nlm.nih.gov/32291316/?dopt=Abstract
Targeting the MAPK pathway by combined inhibition of BRAF and MEK has increased overall survival in advanced BRAF-mutant melanoma in both therapeutic and...
targetingupregulationresistancemapkinhibitors
https://www.jci.org/articles/view/43304/sd/1
jcihgfupregulationangiogenesismice
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.527750/full
The drug resistance of first line Crizotinib molecularly targeted therapy for ROS1 fusion non-small cell lung cancer (NSCLC) was still inevitable. Whether it...
frontiersfusionmediatesimmunogenicityupregulation
https://pubmed.ncbi.nlm.nih.gov/33596420/
Aberrant expression of nuclear transporters and deregulated subcellular localization of their cargo proteins are emerging as drivers and therapeutic targets of...
cancerassociatedexportinupregulationrepressive
https://pubmed.ncbi.nlm.nih.gov/15548727/
We previously demonstrated that cyclic stretch of cardiac myocytes activates paracrine signaling via vascular endothelial growth factor (VEGF) leading to...
tyrosine kinase receptorsstretchinducesupregulationkey
https://www.semanticscholar.org/topic/upregulation-of-LTD/5216203
semantic scholarupregulationltd
https://elifesciences.org/articles/17823
Analyses based on the mouse model of a human genetic disease reveal that the neuron production of cerebral tissue can be boosted by escalated signaling between...
upregulationneurovascularcommunicationfilaminabrogation
https://pubmed.ncbi.nlm.nih.gov/34718343/
The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family includes nine members with aggrecan-degrading activity, i.e., ADAMTS1, 4, 5,...
synergisticupregulationaggrecanasecytokines
https://www.wikidata.org/wiki/Q64008447
article published in 2001
the boneupregulationexpressionwithinmarrow
https://pubmed.ncbi.nlm.nih.gov/38942338/
Obesity is a risk factor for developing severe COVID-19. However, the mechanism underlying obesity-accelerated COVID-19 remains unclear. Here, we report...
upregulationinflammatorygenespathwayslinks
https://www.globenewswire.com/news-release/2025/12/08/3201537/19782/en/CytoDyn-to-Showcase-PD-L1-Upregulation-and-Improved-Survival-in-Metastatic-Triple-Negative-Breast-Cancer-at-the-San-Antonio-Breast-Cancer-Symposium.html
Leronlimab treatment is associated with upregulation of PD-L1 in circulating tumor cells and cancer-associated macrophage-like cells Remarkably longer...
showcasepdupregulationimproved