upregulation - Robuta Search

https://www.jci.org/articles/view/43772/table/1 JCI - Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2... https://pmc.ncbi.nlm.nih.gov/articles/PMC10873620/ Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell... Lipid droplet (LD) accumulation is common in clear cell renal cell carcinoma (ccRCC), providing survival advantage and association with aggressiveness.... https://pmc.ncbi.nlm.nih.gov/articles/PMC7828641/ FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon... Cancer initiating cells (CICs) drive tumor formation and drug-resistance, but how they develop drug-resistance characteristics is not well understood. In this... https://www.spandidos-publications.com/10.3892/ijmm.2012.1192 Gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP-1 International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease. gambogic acid invasion osteosarcoma via upregulation https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2020.584839/full Frontiers | Metabolic Disorder of Extracellular Matrix Mediated by Decorin Upregulation Is... Background and Objective: Diffuse brain arteriovenous malformations (BAVMs) are mixed up with normal brain parenchyma and therefore increase the difficulty o... metabolic disorder extracellular matrix frontiers https://www.jci.org/articles/view/43772/figure/5 JCI - Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2... https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2024-00534&r=1 Revumenib in Treating Patients with Relapsed or Refractory Leukemia Associated with Upregulation of... Revumenib in Treating Patients with Relapsed or Refractory Leukemia Associated with Upregulation of HOX Genes https://pmc.ncbi.nlm.nih.gov/articles/PMC3736531/ Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal... Colorectal cancer (CRC) is a serious public health problem that results due to changes of diet and various environmental stress factors in the world. Curcumin... https://www.spandidos-publications.com/10.3892/ol.2016.4164 Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells... Oncology Letters is an international journal devoted to Experimental and Clinical Oncology. hepatocellular carcinoma upregulation prex2 https://pmc.ncbi.nlm.nih.gov/articles/PMC4156438/ Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency - PMC Single nucleotide polymorphisms (SNPs) in the FK506 binding protein 5 (FKBP5) gene combine with traumatic events to increase risk for post-traumatic stress and... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.975847/full Frontiers | NT5E upregulation in head and neck squamous cell carcinoma: A novel biomarker on... Despite tremendous progress made in the diagnosis and managements, head and neck squamous cell carcinoma (HNSC) remains a global medical dilemma with dismal ... https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.1084108/full Frontiers | Role of 5-HT1A-mediated upregulation of brain indoleamine 2,3 dioxygenase 1 in the... The reduced antidepressant and antihyperalgesic effects of selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine during maintenance treatment ha... indoleamine 2 3 dioxygenase 1 https://www.jci.org/articles/view/142842 JCI - Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia hematopoietic stem cell https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.749673/full Frontiers | Upregulation of HSPA1A/HSPA1B/HSPA7 and Downregulation of HSPA9 Were Related to Poor... The human HSP70 family is a member of the heat shock proteins (HSPs), consisting of 13 members encoded by the HSPA genes. HSPs play important roles in regula... https://pmc.ncbi.nlm.nih.gov/articles/PMC10505611/ NAD+ exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in... Hypertension is characterized by endothelial dysfunction and arterial stiffness, which contribute to the pathogenesis of atherosclerotic cardiovascular... https://www.jci.org/articles/view/43772/figure/3 JCI - Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2... https://www.jci.org/articles/view/130272 JCI - Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia graft versus host disease https://www.spandidos-publications.com/10.3892/mmr.2013.1477/abstract Decreased expression of miR-430 promotes the development of bladder cancer via the upregulation of... Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery. https://www.spandidos-publications.com/10.3892/or.2013.2713/abstract Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. ibuprofen enhances trail induced apoptosis https://pmc.ncbi.nlm.nih.gov/articles/PMC5059611/ Upregulation of Heme Oxygenase-1 in Response to Wild Thyme Treatment Protects against Hypertension... High blood pressure is the most powerful contributor to the cardiovascular morbidity and mortality, and inverse correlation between consumption of... https://www.spandidos-publications.com/or/33/3/1319?text=fulltext Upregulation of AIOLOS induces apoptosis and enhances etoposide chemosensitivity in Jurkat leukemia... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. https://www.spandidos-publications.com/10.3892/etm.2015.2550 Simvastatin reverses cardiomyocyte hypertrophy via the upregulation of phosphatase and tensin... Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine. simvastatin reverses cardiomyocyte hypertrophy via https://www.jci.org/articles/view/34015/pdf JCI - Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their... https://elifesciences.org/reviewed-preprints/89573 Replication stress inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in... replication stress elf3 upregulation https://pmc.ncbi.nlm.nih.gov/articles/PMC2918694/ Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range... Glutamate neurotransmission is highly regulated, largely by glutamate transporters. In the spinal cord, the glutamate transporter GLT-1 is primarily... https://www.deutsche-digitale-bibliothek.de/item/EXZYGBOX7PEVUVJ4R2IYUEXSQ3OUTOER Mitochondrial BNIP3 upregulation precedes endonuclease G translocation in hippocampal neuronal... endonuclease g mitochondrial bnip3 upregulation translocation https://www.spandidos-publications.com/10.3892/or.2015.4011/abstract Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. https://pmc.ncbi.nlm.nih.gov/articles/PMC12372287/ Locus coeruleus tonic upregulation increases selectivity to inconspicuous auditory information in... Sensory processing requires selectivity to salient sensory input. Many autistic individuals report different sensory processing, which has been associated with... locus coeruleus tonic upregulation increases https://www.jci.org/assets/340746/powerpoint JCI - Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies neuropilin 1 jci upregulation elicits https://www.spandidos-publications.com/10.3892/or.2014.3677?text=fulltext Upregulation of AIOLOS induces apoptosis and enhances etoposide chemosensitivity in Jurkat leukemia... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. https://elifesciences.org/articles/58341 Female-biased upregulation of insulin pathway activity mediates the sex difference in Drosophila... The ability to adjust body size in response to diet is greater in Drosophila females than males because of a sex difference in the nutrient-dependent... https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.891665/full Frontiers | CNTN-1 Upregulation Induced by Low-Dose Cisplatin Promotes Malignant Progression of... Tumor metastasis and invasion are the main impediments of lung adenocarcinoma successful treatment. Previous studies demonstrate that chemotherapeutic agents... https://www.sciencedaily.com/releases/2020/06/200629120126.htm How upregulation of a single gene by SARS-CoV-2 can result in a cytokine storm | ScienceDaily Changes in gene expression suggest possible therapies to prevent and treat COVID-19 based on dexamethasone, calcitriol (vitamin D) and tocopherol (vitamin E)... https://pmc.ncbi.nlm.nih.gov/articles/PMC9695946/ Anticancer Effects of Thymoquinone through the Antioxidant Activity, Upregulation of Nrf2, and... The variety of therapies available for treating and preventing triple-negative breast cancer (TNBC) is constrained by the absence of progesterone receptors,... through the antioxidant activity anticancer effects thymoquinone https://www.spandidos-publications.com/10.3892/or.2014.3526/abstract Global expression profile in low grade meningiomas and schwannomas shows upregulation of PDGFD,... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. https://www.jci.org/assets/340745/powerpoint JCI - Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies neuropilin 1 jci upregulation elicits https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1400270/full Frontiers | MMP-9 upregulation may predict hemorrhagic transformation after endovascular... Background: Hemorrhagic transformation (HT) is a serious complication after endovascular thrombectomy (EVT) for patients with acute ischemic stroke (AIS). We... mmp 9 hemorrhagic transformation frontiers upregulation may https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2023.1272899/full Frontiers | Upregulation of LRRK2 following traumatic brain injury does not directly phosphorylate... Phosphorylated microtubule-associated protein tau (tau) aggregates are a pathological hallmark of various neurodegenerative diseases, including chronic traum... traumatic brain injury https://www.mdpi.com/1422-0067/22/12/6307 Transcriptional Profiling Identifies Upregulation of Neuroprotective Pathways in Retinitis... Hereditary retinal degenerations like retinitis pigmentosa (RP) are among the leading causes of blindness in younger patients. To enable in vivo investigation... transcriptional profiling identifies upregulation neuroprotective https://www.spandidos-publications.com/10.3892/or.2016.4899?text=fulltext PMA/IONO affects diffuse large B-cell lymphoma cell growth through upregulation of A20 expression Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. diffuse large b cell lymphoma https://www.jci.org/articles/view/43772/citations JCI - Citations to Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated... https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.584184/full Frontiers | Upregulation of Nucleotide-Binding Oligomerization Domain-, LRR- and Pyrin... Neuronal injuries are accompanied by release and accumulation of damage-associated molecules, which in turn may contribute to activation of the immune system... frontiers upregulation nucleotide binding oligomerization https://pmc.ncbi.nlm.nih.gov/articles/PMC12411320/ Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT... Epitalon, a naturally occurring tetrapeptide, is known for its anti-aging effects on mammalian cells. This happens through the induction of telomerase enzyme... human cell lines https://www.spandidos-publications.com/10.3892/ijmm.2020.4611/abstract Upregulation of Nav1.7 by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease. https://www.spandidos-publications.com/10.3892/or.2016.5132?text=fulltext Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. read through https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.989263/full Frontiers | NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma Phosphoribosyl pyrophosphate synthetase 1 (PRPS1) is the first enzyme in the de novo purine nucleotide synthesis pathway and is essential for cell developmen... https://www.jci.org/articles/view/43772/figure/2 JCI - Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2... https://pmc.ncbi.nlm.nih.gov/articles/PMC12560501/ Fumarate-based drugs protect against neuroinflammation via upregulation of anti-ferroptotic... Ferroptosis is defined as iron dependent non-apoptotic cell death. It is based on peroxidation of polyunsaturated phospholipids and subsequent membrane... fumarate based drugs protect https://www.spandidos-publications.com/10.3892/ijmm.2012.1002/abstract PI3K/Akt signaling pathway-induced heme oxygenase-1 upregulation mediates the adaptive... International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease. heme oxygenase 1 pi3k akt signaling pathway https://www.spandidos-publications.com/10.3892/ijmm.2012.1185/abstract Involvement of Nrf2 activation in the upregulation of S100A9 by exposure to inorganic arsenite International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease. https://www.mdpi.com/1422-0067/23/24/16037 Muscle Regeneration in Holothurians without the Upregulation of Muscle Genes The holothurian Eupentacta fraudatrix is capable of fully restoring its muscles after transverse dissection. Although the regeneration of these structures is... muscle regeneration holothurians without upregulation https://www.spandidos-publications.com/10.3892/br.2013.169/abstract Upregulation of proinflammatory genes in skin lesions may be the cause of keloid formation (Review) Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology. https://pmc.ncbi.nlm.nih.gov/articles/PMC12165936/ Gambogic acid suppresses osteosarcoma progression through upregulation of FOXO3a - PMC Osteosarcoma is a prevalent bone cancer in children and adolescents, posing significant treatment challenges due to its high metastatic potential and... gambogic acid osteosarcoma progression upregulation foxo3a https://pmc.ncbi.nlm.nih.gov/articles/PMC12677082/ Coordinated upregulation of PABPC1L and SNHG lncRNAs defines a tumor-specific expression module in... Nonsense-mediated mRNA decay (NMD) has an important role in the pathoetiology of cancer, including colorectal cancer (CRC). Identification of the lncRNAs... https://www.jci.org/articles/view/43772/usage JCI - Usage information: Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with... https://www.mdpi.com/2077-0383/11/14/4060 Programmed Cell Death Protein-1 Upregulation in Response to SARS-CoV-2 in Juvenile Idiopathic... Currently, data regarding the impact of COVID-19 disease (caused by SARS-CoV-2) on patients with childhood rheumatic diseases are significantly limited. To... programmed cell death https://www.mdpi.com/1422-0067/23/9/5125 Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells Blockers of the renin-angiotensin system (RAS) have been reported to increase the angiotensin converting enzyme (ACE)2, the cellular receptor of SARS-CoV-2,...