Sponsor of the Day:
Jerkmate
https://www.nature.com/articles/s41590-025-02376-4?error=cookies_not_supported&code=49b961b8-7d0a-49b6-a2cd-3faf391c54dd
Targeting autocrine retinoic acid signaling by ALDH1A2 inhibition enhances antitumor dendritic cell...
Jan 5, 2026 - Strategies to stimulate dendritic cell (DC) activity, such as ex vivo generation and priming of DC vaccines, have been explored as cancer immunotherapies owing...
dendritic celltargetingautocrineacidsignaling
https://www.newswise.com/articles/aacr-zedoresertib-and-lunresertib-combination-shows-promising-antitumor-activity
AACR: Zedoresertib and Lunresertib Combination Shows Promising Antitumor Activity | Newswise
Apr 20, 2026 - • Phase I trial provides early clinical proof-of-concept supporting the combination of zedoresertib and lunresertib in certain advanced solid tumors •...
shows promisingaacrcombinationantitumoractivity
https://www.frontiersin.org/research-topics/80550/age-related-lymph-node-remodeling-and-its-impact-on-antitumor-immune-surveillance-and-cancer-dissemination
Frontiers | Age-Related Lymph Node Remodeling and Its Impact on Antitumor Immune Surveillance and...
Lymph nodes serve as critical hubs of adaptive immunity, coordinating the activation, expansion, and trafficking of immune cells essential for effective anti...
age relatedlymph nodeimmune surveillancefrontiersremodeling
https://www.jci.org/articles/view/196722
JCI - Targeting the N-acetyltransferase 10/DKK2 axis enhances CD8+ T cell antitumor activity in...
jci targeting10axisenhancescd8
https://insight.jci.org/articles/view/197404
JCI Insight - DNA delivered by lipid nanoparticles induces CD8+ T cell–dependent antitumor...
jci insightlipid nanoparticlesdnadeliveredinduces
https://www.jci.org/articles/view/196379
JCI - MAP4K2 suppresses antitumor immunity in a pancreatic cancer model by promoting Treg...
pancreatic cancerjcisuppressesantitumorimmunity
https://www.jci.org/articles/view/198843
JCI - STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor...
blood brain barrierjcistinginducedopening