Robuta

Owing to retained hepatic phenotypes and functions, human three-dimensional (3D) hepatic models established with diverse hepatic cell types are thought to re...

Abstract page for arXiv paper 2411.11515: Cascaded Diffusion Models for 2D and 3D Microscopy Image Synthesis to Enhance Cell Segmentation

Our systems approach to model follicle metabolism can guide future experimental studies to validate the model results and improve oocyte maturation approaches...

Parkinson's disease (PD) is a neurodegenerative debilitating disorder characterized by progressive disturbances in motor, autonomic and psychiatric functions....

Brain neurons exhibit complex electroresponsive properties - including intrinsic subthreshold oscillations and pacemaking, resonance and phase-reset - which ...

This study demonstrates, for the first time, the successful targeting of mCALR with CAR-T cells as a therapeutic strategy for MPNs. The chosen construct shows...

Medical School of Chinese People's Liberation Army. This study presents two crucial experimental techniques: the construction of a murine wound model for...

Inflammatory and oxidative processes are tightly regulated by innate and adaptive immune systems, which are involved in the pathology of a diversity of chronic...

BRD-810 inhibits the MCL1 protein and reactivates apoptosis in tumor cells, displaying therapeutic potential in animal models.

Melanoma clinical outcomes emerge from incompletely understood genetic mechanisms operating within the tumor and its microenvironment. Here, we used...

Gaucher disease is a rare metabolic disorder, in which a mutation of the enzyme glucocerebrosidase (GBA1) causes buildup of its substrate glucosylceramide and...

Congenital disorders of glycosylation (CDG) are inherited metabolic diseases characterized by mutations in enzymes involved in different steps of protein gly...

BMC Psychiatry welcomed submissions for the Collection Stem cell models in psychiatry. The use of stem cells to treat psychiatric disorders is a new concept ...

The cell concentration measurement on a culture assay using bioimpedance is a very useful tool, but it is complex to translate impedance to cell concentration...

Currently available cell culture media may not reproduce the in vivo metabolic environment of tumors. To demonstrate this, we compared the effects of a new...

Cytokines are soluble proteins secreted by a wide variety of cells in the body, playing crucial roles in many physiological responses and are involved in the...

An integrated stem cell-based disease modeling and computational approach demonstrates how proximal airway epithelium is critical for SARS-CoV-2 infectivity...

Cell Systems 3-D is a Biotechnology Business Which Develops Organotypic 3-D Cell Models of Human, Veterinary and Insect Origins. Call (281) 389-1861.

Deep learning improves estimation of T cell receptor cohort frequencies and learns the rules of VDJ recombination, potentially making it helpful for vaccine...

Prof.dr. B. Van de Water dr. G. Callegaro

Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. It is a medically and socially complex, multisystem illness that...

Aging is associated with impairment in skeletal muscle mass and contractile function, predisposing to fat mass gain, insulin resistance and diabetes. The...

Sickle cell crisis, a painful blood blockage common in people with sickle cell disease, isn't just about sickle-shaped red blood cells that block capillaries....

Aug 10, 2025 - In recent decades, immunotherapy has undergone extensive developments for oncologic therapy applications. Dendritic cells (DCs) plays a fundamental role in...

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the...