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Endothelial cells (ECs) not only form passive blood conduits but actively contribute to nutrient transport and organ homeostasis. The role of ECs in glucose...

Interaction of HIV capsids with the cellular protein cleavage-and-polyadenylation factor 6 at the inner side of nuclear pores promotes nuclear entry of the...

The increasing knowledge of barrier tissue-resident memory macrophages and trained innate immunity (TII) will help develop both nontarget-specific and...

Murine macrophages have been described as possessing complement receptors for C3b and iC3b. These binding activities have been assumed to be due to the...

scientific article published on September 1, 1984

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Innate immune cells including macrophages and neutrophils have unique properties that allows them to quickly accumulate in large numbers at the site of...

Adaptation of the innate immune system has been recently acknowledged, explaining sustained changes of innate immune responses. Such adaptation is termed tra...

The ontogeny of macrophages in most organ/tissues in human body has been proven. Due to the limited number and inaccessibility of synovial macrophages (SM), ...

scientific article published on March 1, 1977

Heart injury has been characterized by the irreversible loss of cardiomyocytes comprising the contractile tissues of the heart and thus strategies enabling...

Cross-presentation allows dendritic cells (DCs) to present peptides derived from endocytosed Ags on MHC class I molecules, which is important for activating...

Carisma is pioneering the development of CAR-Macrophages and CAR-Monocytes, disruptive approaches to solid tumor immunotherapy treatment.

Multiplexed mass spectrometry shows how the autophagy gene Atg16l1 regulates macrophage innate immunity against intracellular bacterial pathogens by modulating...

Triple-negative breast cancer (TNBC) is an aggressive tumor with limited treatment options and poor prognosis. We applied the in vivo phage display technology...

Effect of tumor-associated macrophages on gastric cancer stem cell in omental milky spots and lymph node micrometastasis. by Chi Zhang, Xiang Hu, Xiao-Yu Liu,...

Complex regional pain syndrome type I (CRPS-I) is characterized by intractable chronic pain. Poor understanding of the underlying mechanisms of CRPS-I accounts...

Thymic macrophages are unique phagocytes with antigen-presenting abilities that comprise a Timd4+ subset of embryonic origin located in the cortex and a...

Researchers in France have discovered that, though a tattoo may be forever, the skin cells that carry the tattoo pigment are not. Instead, the researchers say,...

Comparison of contrast agents for atherosclerosis imaging using cultured macrophages: FDG versus ultrasmall superparamagnetic iron oxide. by Tomoko Satomi,...

Mammalian STC1 decreases the mobility of macrophages and diminishes their response to chemokines. In the current experiments, we sought to determine the impact...

Researchers mapped Zika virus infections in the lymph nodes to determine how the Zika virus enters from different points in the skin and disseminates through...

Osteoarthritis (OA) is a progressive joint disease characterized by inflammation and cartilage destruction, and its progression is closely related to...

Skin malignant melanoma is a highly aggressive skin tumor, which is also a major cause of skin cancer-related mortality. It can spread from a relatively smal...