https://pubmed.ncbi.nlm.nih.gov/30559476/
Microglia, the specialized innate immune cells of the CNS, play crucial roles in neural development and function. Different phenotypes and functions have been...
humanmicrogliaregionalheterogeneityphenotypes
https://pubmed.ncbi.nlm.nih.gov/23590217/
Amongst patients with adult-onset asthma, three subphenotypes can be identified with distinct clinical and inflammatory characteristics. These subphenotypes...
adult onsetthreephenotypesasthma
https://pubmed.ncbi.nlm.nih.gov/18257708/?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
Plant genomes encode hundreds of proteases, which represent dozens of unrelated families. The biological role of these proteases is mostly unknown, but mutant...
plantproteasesphenotypesmolecularmechanisms
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2015.00823/full
Plastids in the leaf epidermal cells of plants are regarded as immature chloroplasts that, like mesophyll chloroplasts, undergo binary fission. While mesophy...
frontiersarabidopsisminemutationcauses
https://pubmed.ncbi.nlm.nih.gov/34080738/
Critical COVID-19 seems to be characterized by an immune profile of activated and exhausted T cells and monocytes. This immune phenotype may influence the...
criticalcovidassociateddistinctleukocyte
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2025.1475054/full
ObjectiveNetherton syndrome (NS) is a rare hereditary dermatosis, and the correlation between genotype and phenotype in this disease warrants further investi...
the rolefrontiersmutationdistributionphenotypes
https://www.news-medical.net/news/20221206/Machine-learning-analysis-suggests-that-there-are-four-sub-phenotypes-of-long-COVID.aspx
Researchers identified PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)] sub-phenotypes depending on conditions diagnosed within 1 to 3 months...
machine learningthere areanalysissuggestsfour
https://pubmed.ncbi.nlm.nih.gov/40335489/
Blood cell phenotypes are routinely tested in healthcare to inform clinical decisions. Genetic variants influencing mean blood cell phenotypes have been used...
blood cellgenomewideanalysesvariance
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2017.00042/full
Maternal control of seed size in the common bean provides an opportunity to study genotype-independent seed weight effects on early seedling growth and devel...
maternal effectsfrontiersseedphenotypesreciprocal
https://pubmed.ncbi.nlm.nih.gov/41279819/
Immunotherapy has potential for impactful cancer cures by empowering patients' own immune cells. We developed a radio-immunotherapy regimen that can cure large...
t cellsdivergentroledistinctmetabolic
https://pubmed.ncbi.nlm.nih.gov/28157695/
Bladder cancer is one of the most common urothelial tumors worldwide. While there are some progresses on early bladder cancer detection, patients' mortalities...
increasedlncrnamalignantphenotypesbladder
https://www.jmir.org/2024/1/e51269/citations
Background: Passive sensing through smartphone keyboard data can be used to identify and monitor symptoms of mood disorders with low participant burden....
internet researchjournalmedicaldigitalphenotypes
https://pubmed.ncbi.nlm.nih.gov/31747945/
The resurgence of immune therapies in cancer medicine has elicited a corresponding interest in understanding the basis of patient response or resistance to...
genome instabilityimpactphenotypesimmunotherapy
https://pubmed.ncbi.nlm.nih.gov/31751773/
Within the spectrum of autoimmune liver diseases, there are patients who manifest features of more than one disease, which was previously identified as having...
igg igmplasma cellsratiosliverreveal
https://www.mdpi.com/2077-0383/10/14/3061
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a progressive heart condition which causes fibro-fatty myocardial scarring, ventricular arrhythmias,...
in aalteredelectricalbiomolecularimmunologic
https://pubmed.ncbi.nlm.nih.gov/32220891/
This study identified genomic features associated with prognosis in metastatic castration-sensitive disease that may aid in molecular classification and...
oncogenicgenomicalterationsclinicalphenotypes
https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2014.00095/full
Autism Spectrum Disorders (ASD) are neurodevelopmental disorders with multifactorial origin characterized by social communication and behavioural perseverati...
frontiersmappingpathologicalphenotypesreelin
https://ilife.jp/nac/the-antioxidant-n-acetylcysteine-prevents-cortical-neuropathological-phenotypes-caused-by-adolescent-%CE%B4-9-tetrahydrocannabinol-exposure-in-male-rats/
Translational Psychi
antioxidantacetylcysteinecorticalphenotypescaused
https://pubmed.ncbi.nlm.nih.gov/30323968/
Osteosarcoma (OS) is a highly aggressive mesenchymal malignancy and the most common primary bone tumor in the pediatric population. OS frequently presents with...
transglutaminasemetastaticstemlikephenotypes
https://pubmed.ncbi.nlm.nih.gov/28349252/
Prevalence of hypertension and especially ISH in obese children and in children with central obesity in Greece are among the highest reported in Europe. Future...
by weightprevalencechildhoodhypertensionphenotypes
https://pubmed.ncbi.nlm.nih.gov/26460041/
Evidence from numerous cancers suggests that increased aggressiveness is accompanied by up-regulation of signaling pathways and acquisition of properties...
stem cellprostate cancerbasalsignatureaggressive
https://catalogue.ceh.ac.uk/documents/f463bc5c-bb79-4967-a8dc-f662f57f7020
Phenotypes (growth and phenology) for Scots pine trees in a long-term common garden trial planted in three sites in Scotland, surveyed annually from 2013 to...
long termscots pinemultisitetrialscotland
https://pubmed.ncbi.nlm.nih.gov/35878816/
Phenotypes with congestive features demonstrated increased risk profiles. Heart failure is a heterogenous classification which requires further work to...
heart failurethe spectrumclinicalphenotypesacross
https://pubmed.ncbi.nlm.nih.gov/20876876/
Results show that MC1R variants, hair color, and number of nevi were jointly associated with melanoma risk in CDKN2A mutation carriers. This joint association...
associationvariantshostphenotypesmelanoma
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003224
Thermally dimorphic fungi like Histoplasma switch between an environmental filamentous form and a host-associated yeast in response to temperature. This study...
rapidgainlosschromosomedrives