https://elifesciences.org/articles/52027
Orthogonal to traditional paradigms that manipulate neuroligin expression level, optogenetic stimulation of tyrosine phosphorylation highlights a role of the...
optogeneticcontrolexcitatorypostsynaptic
https://pubmed.ncbi.nlm.nih.gov/9774334/
Angiogenesis, the sprouting of new blood vessels from pre-existing ones, is an essential physiological process in development, yet also plays a major role in...
crystal structureangiogenesis inhibitorboundfgf
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/egfr-tyrosine-kinase-inhibitor
NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
tyrosine kinase inhibitordefinitionegfrncidictionary
https://pubmed.ncbi.nlm.nih.gov/34044147/?utm_medium=email&_hsenc=p2ANqtz--wD6FtLKHedp0T82ZolwAvcTrQPKtNw4bsndGxw-jHqA-aq5sYlQLVM5H677gROYhjbPk6RSSTtmJ63f66b1ecT5vvaA&_hsmi=141845939&utm_content=141845939&utm_source=hs_email
Mutations in the beta-amyloid protein (APP) cause familial Alzheimer's disease. In hAPP-J20 mice expressing mutant APP, pharmacological inhibition or genetic...
tyrosine phosphatasenmda receptorpresynapticmediatedplasticity
https://www.ncbi.nlm.nih.gov/Structure/pdb/5TT7
Tyrosine-protein kinase SYK2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-5-one
discoverytakorallyavailableinhibitor
https://www.ncbi.nlm.nih.gov/Structure/pdb/1XBB
Tyrosine-protein kinase SYK4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
crystal structuretyrosine kinasesykdomain
https://www.rcsb.org/structure/4FZ7
Crystal structure of spleen tyrosine kinase complexed with 6-((1R,2S)-2-Amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide
spleen tyrosine kinasecrystal structurercsbpdb
https://pubmed.ncbi.nlm.nih.gov/39960754/
Mutations in the kinase and juxtamembrane domains of the MET Receptor Tyrosine Kinase are responsible for oncogenesis in various cancers and can drive...
the metmappingkinasedomainresistance
https://elifesciences.org/articles/05196/peer-reviews
Targeting Abelson kinase can be beneficial for treating disorders characterized by dysregulated Down Syndrome Cell Adhesion Molecule signaling.
peer reviewdscamlevelsactabelson
https://elifesciences.org/articles/82863/figures
pYtags are novel biosensors that can be used to measure the activity of a receptor tyrosine kinase of interest in live cells with high spatiotemporal...
figuresdataenablespatiotemporalmeasurements
https://www.ncbi.nlm.nih.gov/Structure/pdb/6SEQ
Serine/threonine-protein kinase LMTK3
tyrosine kinaselemur
https://pubmed.ncbi.nlm.nih.gov/9935078/?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
The high in vivo stability of L-[18F]FET, its fast brain and tumor uptake kinetics, its low accumulation in nontumor tissue and its ease of synthesis strongly...
synthesisradiopharmacologyfluoroethyltyrosine