https://www.news-medical.net/news/20170203/Single-molecule-detection-of-proteins-in-single-cells.aspx
We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my...
singlemoleculedetectionproteinscells
https://www.news-medical.net/news/20250514/New-technology-maps-molecules-within-single-cells-to-uncover-disease-mechanisms.aspx
Tissues consist of a heterogenous mixture of different cell types, complicating our understanding of their biological functions and studies of disease.
single cellsnewtechnologymapsmolecules
https://www.sciencedaily.com/releases/2016/08/160831142859.htm
An easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue has been identified by researchers: feed them adenosine, a naturally...
a singlestem cellsresearchersusemolecule
https://zenodo.org/records/15031364
Dataset and checkpoint repository for the ICLR 2025 paper "Multi-Modal and Multi-Attribute Generation of Single Cells with CFGen".
single cellsmultimodalattributegeneration
https://elifesciences.org/for-the-press/265ec424/single-cell-asymmetries-control-how-groups-of-cells-form-3d-shapes-together
A new mathematical tool shows that altering one of two asymmetries in the properties of single cells controls how they organise into folded, biological shapes,...
single cellasymmetriescontrolgroupscells
https://pubmed.ncbi.nlm.nih.gov/23859772/
Living cells are exquisitely responsive to mechanical cues, yet how cells produce and detect mechanical force remains poorly understood due to a lack of...
moleculartensionsensorsreportforces
https://www.sciencedaily.com/releases/2015/03/150302123333.htm
Disruptions in brain stability cause disorders such as epilepsy, but precious little is known about homeostasis, the brain's regulatory system. Now a new study...
single cellsneurongroupsmaintainbrain
https://pubmed.ncbi.nlm.nih.gov/35816400/
At the initial stage of carcinogenesis, oncogenic transformation occurs in single cells within epithelial layers. However, the behavior and fate of the newly...
basalextrusionsingleoncogenicmutant
https://sciencedaily.com/releases/2025/02/250211134608.htm
Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent...
a singleamino acidcellular proteindisruption
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.1099271/full
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers globally, with significant cell heterogeneity and poor prognosis. Distant metasta...
single cellepithelial cellsfrontiersprofilingreveals
https://pubmed.ncbi.nlm.nih.gov/35637521/
Tumors are complex tissues of cancerous cells surrounded by a heterogeneous cellular microenvironment with which they interact. Single-cell sequencing enables...
tumor cellsusing machineidentifyingsinglelevel
https://www.ojp.gov/ncjrs/virtual-library/abstracts/characterizing-stutter-single-cells-and-impact-multi-cell-analysis
This article reports on the research methodology and outcomes from a project that characterized PCR artifacts (stutter) in single-cell samples to help generate...
single cellsthe impactstuttermulti