Robuta

Protein Degrader Building Blocks are a collection of crosslinker-E3 ligand conjugates with a pendant functional group for covalent linkage to a target ligand.

scientific article (publication date: November 2003)

Cancer cells require high levels of iron for rapid proliferation, leading to significant upregulation of cell-surface transferrin receptor 1 (TfR1), which...

Viral myocarditis is an inflammation of the heart muscle triggered by direct virus-induced cytolysis and immune response mechanisms with most severe conseque...

Proteasomes and the Ubiquitin-Proteasome System (UPS)

Arvinas is a clinical-stage biotechnology company leading the way in targeted protein degradation therapeutics.

A novel targeted protein degradation system to achieve cell-type-specific enhancement of Wnt signaling.