https://pubmed.ncbi.nlm.nih.gov/31158293/
The models developed and validated in this study provide important prognostic information not captured by previously established clinical and molecular factors...
dna methylationprofilingpredictrecurrencerisk
https://pubmed.ncbi.nlm.nih.gov/37533074/
This meta-analysis confirmed the great potential of DNA methylation-based biomarkers as triage tool for hrHPV-positive women in cervical cancer screening....
dna methylationtriagemarkercolposcopyreferral
https://pubmed.ncbi.nlm.nih.gov/29438328/
Viruses have evolved various mechanisms to evade host immunity and ensure efficient viral replication and persistence. Several DNA tumor viruses modulate host...
dna tumor virusregulationhostmethylation
https://link.springer.com/article/10.1186/s12987-023-00414-7?error=cookies_not_supported&code=c6ee7d33-dd5d-4932-9ad2-14590485ad74
Feb 28, 2023 - Incomplete recovery of blood–brain barrier (BBB) function contributes to stroke outcomes. How the BBB recovers after stroke remains largely unknown.
and strokedna methylationepigeneticsroleeffect
https://www.mdpi.com/2072-6643/17/6/1086
Objective: This in vitro study aimed to investigate the impact of folic acid on DNA methylation and gene expression in adipocytes from subcutaneous adipose...
folic aciddna methylationgenomewideimpact
https://zenodo.org/records/10635657
Patients with pancreatic ductal adenocarcinoma (PDAC) have the lowest survival rate among all cancer patients in Europe. Since western societies have the...
multiomicsdeepclusteringreveals
https://www.frontiersin.org/journals/ecology-and-evolution/articles/10.3389/fevo.2021.781498/full
While differences in methylation patterns of ABC transporters under different environmental conditions and their role in plant growth, development, and respo...
dna methylationabc transportersfrontiersdiffersnative
https://pubmed.ncbi.nlm.nih.gov/30140739/
Curtailed sleep promotes weight gain and loss of lean mass in humans, although the underlying molecular mechanisms are poorly understood. We investigated the...
sleep lossacuteresultstissuespecific
https://pubmed.ncbi.nlm.nih.gov/30644360/?dopt=Abstract
Direct reprogramming of fibroblasts to neurons induces widespread cellular and transcriptional reconfiguration. Here, we characterized global epigenomic...
dna methylationglobalremodelingdirectreprogramming
https://www.endocrine.org/journals/jcem-case-reports/adrenocortical-tumor-in-kcnj5-and-dna-methylation-of-cyp11b2
The authors present a case of unilateral primary aldosteronism with pathogenic variants in KCNJ5 and suppressed CYP11B2 expression.
adrenocortical tumorpathogenic variantassociateddna
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1065417/full
ABSTRACTObjective: We explored the DNA methylation and messenger RNA (mRNA) co-expression network and hub genes in first-episode, drug-naive adolescents with...
dna methylationfrontierscoexpressionnetwork
https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2016.01675/full
Differences in drought stress tolerance within diverse rice genotypes have been attributed to genetic diversity and epigenetic alterations. DNA methylation i...
dna methylationchanges twofrontiersgenomewide
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.01082/full
Aims: Long non-coding RNA IRAIN (lncRNA IRAIN) plays a critical role in numerous malignancies. However, the function of lncRNA IRAIN in renal carcinoma (RC) ...
non coding rnafrontierslongvegfaexpression
https://pubmed.ncbi.nlm.nih.gov/28473536/
The majority of CpG dinucleotides in the human genome are methylated at cytosine bases. However, active gene regulatory elements are generally hypomethylated...
cytosine methylationimpactdnabindinghuman
https://methprimer.com/
MethPrimer is a free online tool for designing primers for DNA methylation studies using bisulfite-converted DNA.
dna methylationprimer design
https://pubmed.ncbi.nlm.nih.gov/25425661/
DNA methylation in Arabidopsis thaliana is maintained by at least four different enzymes: DNA methyltransferase1 (MET1), chromomethylase3 (CMT3), domains...
chromatinremodelerfamilyproteinsrequired
https://pubmed.ncbi.nlm.nih.gov/21245466/
Plant viruses are excellent tools for studying microbial-plant interactions as well as the complexities of host activities. Our study focuses on the role of C2...
degradationsuppressdna