https://pubmed.ncbi.nlm.nih.gov/1776122/
In recent years, there have been a number of advances in the diagnosis and management of patients with malignant melanoma of the posterior uvea (ciliary body...
uveal melanomamanagementposterior
https://pubmed.ncbi.nlm.nih.gov/40418200/
Re: Gelmi et al.: Survival in patients with uveal melanoma is linked to genetic variation at HERC2 single nucleotide polymorphism rs12913832 (Ophthalmology....
et aluveal melanomagelmisurvivalpatients
https://www.aging-us.com/figure/103779/f1
Immune scores and stromal scores are associated with Uveal Melanoma (UM) clinical subtypes, like histological type, metastasis, etc. (A) Distribution of immune...
developmentvalidationimmunestromalprognostic
https://www.pharmaceutical-technology.com/data-insights/likelihood-of-approval-uveal-melanoma/
Uveal Melanoma disease is an indication for drug development with over 80 pipeline drugs currently active according to GlobalData.
uveal melanomadrugslikelihoodapproval
https://www.aacr.org/professionals/research-funding/grantees/revolutionizing-uveal-melanoma-treatment-scandium-ii-trial-combines-chemotherapy-and-immunotherapy-for-promising-results/
Roger Olofsson Bagge, MD, PhD, recipient of the 2021 AACR-OMF Career Development Award, in honor of Robert C. Allen, MD, shares how the recent SCANDIUM-II...
uveal melanomarevolutionizingtreatmentscandiumii
https://www.sigmaaldrich.com/US/en/tech-docs/paper/1331244
A potential role for TGFbeta in the regulation of uveal melanoma adhesive interactions with the hepatic endothelium. by Julia K L Woodward, Ian G Rennie, J...
potentialroletgfbetaregulationuveal
https://curie.fr/publications/hdac-inhibition-increases-hla-class-i-expression-uveal-melanoma
The treatment of uveal melanoma (UM) metastases or adjuvant treatment may imply immunological approaches or chemotherapy. It is to date unknown how epigenetic...
hdac inhibitionuveal melanomaincreaseshlaclass
https://curie.fr/publications/validation-prognostic-staging-metastatic-uveal-melanoma-collaborative-study-european-ophthalmic
Retrouvez Validation of a Prognostic Staging for Metastatic Uveal Melanoma: A Collaborative Study of the European Ophthalmic Oncology Group. L'Institut Curie...
uveal melanomavalidationprognosticstagingmetastatic
https://curie.fr/publications/germline-mbd4-mutations-and-predisposition-uveal-melanoma
Abstract Background Uveal melanoma (UM) arises from malignant transformation of melanocytes in the uveal tract of the eye. This rare tumor has a poor outcome...
uveal melanomainstitut curiegermlinemutationspredisposition
https://curie.fr/publications/outlier-response-anti-pd1-uveal-melanoma-reveals-germline-mbd4-mutations-hypermutated-tumors
AbstractMetastatic uveal melanoma is a deadly disease with no proven standard of care. Here we present a metastatic uveal melanoma patient with an exceptional...
uveal melanomaoutlierresponseantireveals
https://pubmed.ncbi.nlm.nih.gov/36624219/
These results suggest manageable toxicity and encouraging clinical activity of single-agent LXS196 in patients with MUM.
protein kinase cphasetrial
https://curie.fr/publications/uveal-melanoma-patient-derived-xenografts
The prognosis of uveal melanoma (UM) remains poor due to a high risk of metastatic disease. No effective therapies have been described for metastatic UM, and...
uveal melanomainstitut curiepatientderivedxenografts